Emerging approaches for decoding neuropeptide transmission
November 2022 "Neuropeptides produce robust effects on behavior across species, and recent research has benefited from advances in...
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GPCR News
- Oct 1, 2022
- 1 min
Reversible Photocontrol of Dopaminergic Transmission in Wild-Type Animals
October 2022 "Understanding the dopaminergic system is a priority in neurobiology and neuropharmacology. Dopamine receptors are involved...
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GPCR News
- Oct 1, 2022
- 1 min
Differences across sexes on head-twitch behavior and 5-HT2A receptor signaling in C57BL/6J mice
October 2022 "Psychedelics, also known as classical hallucinogens, affect processes related to perception, cognition and sensory...
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GPCR News
- Oct 1, 2022
- 1 min
Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors
October 2022 "The prefrontal cortex (PFC) is a hub for cognitive control, and dopamine profoundly influences its functions. In other...
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GPCR News
- Oct 1, 2022
- 1 min
Comparative study of neuropeptide signaling systems in Hemiptera
October 2022 "Numerous physiological processes in insects are tightly regulated by neuropeptides and their receptors. Although they form...
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GPCR News
- Oct 1, 2022
- 1 min
G protein-biased GPR3 signaling ameliorates amyloid pathology in a preclinical Alzheimer's disease..
October 2022 "Biased G protein-coupled receptor (GPCR) ligands, which preferentially activate G protein or β-arrestin signaling pathways,...
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GPCR News
- Sep 1, 2022
- 1 min
Neuropeptide S Encodes Stimulus Salience in the Paraventricular Thalamus
September 2022 "Evaluation of stimulus salience is critical for any higher organism, as it allows for prioritizing of vital information,...
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GPCR News
- Sep 1, 2022
- 1 min
Although the cannabinoid type-2 receptor (CB2) is highly expressed in the immune system, emerging...
September 2022 Cannabinoid type-2 receptors: An emerging target for regulating schizophrenia-relevant brain circuits "Although the...
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GPCR News
- Sep 1, 2022
- 1 min
A central alarm system that gates multi-sensory innate threat cues to the amygdala
September 2022 "Perception of threats is essential for survival. Previous findings suggest that parallel pathways independently relay...
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GPCR News
- Sep 1, 2022
- 1 min
Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease
September 2022 "Parkinson’s disease (PD) as a progressive neurodegenerative disorder arises from multiple genetic and environmental...
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GPCR News
- Sep 1, 2022
- 1 min
Targeting mGluR2/3 for treatment of neurodegenerative and neuropsychiatric diseases
September 2022 "Glutamate is the primary excitatory neurotransmitter in the brain and plays critical roles in all aspects of neuronal...
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GPCR News
- Aug 1, 2022
- 2 min
GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal...
August 2022 GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal regeneration after optic...
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GPCR News
- Aug 1, 2022
- 1 min
Aβ peptides stabilize GPCRs in inactive form and trigger inverse agonism in Alzheimer's disease
August 2022 "Several G-protein coupled receptors (GPCR) are upregulated in Alzheimer's Disease (AD), which ought to facilitate...
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GPCR News
- Dec 31, 2021
- 1 min
A role for BET proteins in regulating basal, dopamine-induced and cAMP/PKA-dependent ...
A role for BET proteins in regulating basal, dopamine-induced and cAMP/PKA-dependent transcription in rat striatal neurons The activity...
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GPCR News
- Dec 20, 2021
- 2 min
Synaptic integration of subquantal neurotransmission by co-localized G protein coupled receptors in
In presynaptic terminals, membrane-delimited Gi/o-mediated presynaptic inhibition is ubiquitous and acts through Gβγ to inhibit Ca2+...
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GPCR News
- Dec 13, 2021
- 1 min
GPCR voltage dependence controls neuronal plasticity and behavior
G-protein coupled receptors (GPCRs) play a paramount role in diverse brain functions. Almost 20 years ago, GPCR activity was shown to be...
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GPCR News
- Dec 9, 2021
- 1 min
Chemogenetic stimulation of the G i pathway in astrocytes suppresses neuroinflammation
Engineered G protein-coupled receptors (GPCRs) are commonly used in chemogenetics as designer receptors exclusively activated by designer...
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GPCR News
- Dec 6, 2021
- 2 min
Lysophosphatidic Acid and Several Neurotransmitters Converge on Rho-Kinase 2 Signaling to Manage...
Lysophosphatidic Acid and Several Neurotransmitters Converge on Rho-Kinase 2 Signaling to Manage Motoneuron Excitability Intrinsic...
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GPCR News
- Dec 5, 2021
- 1 min
Latrophilin-1 drives neuron morphogenesis and shapes chemo- and mechanosensation-dependent ...
Latrophilin-1 drives neuron morphogenesis and shapes chemo- and mechanosensation-dependent behavior in C. elegans via a trans function...
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GPCR News
- Dec 1, 2021
- 1 min
Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the ...
Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the range of μg/L in C. elegans The aim of this...
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