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472 results found for "Stefano Moro"
- 📰 GPCR Weekly News, February 19 to 25, 2024
G-protein coupled receptor promotes the restoration of tension in epithelial cells GPCR Binders, Drugs, and more the round: SMA-like copolymers and SMALPs as a platform for investigating GPCRs Reviews, GPCRs, and more
- GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal...
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- Nanobodies: New Dimensions in GPCR Signaling Research
All the above lightly represent the potential applications of Nbs to facilitate the development of more To know more about this report check this link. References: Jin, B.
- Regulator of G Protein Signaling 20 Correlates with Long Intergenic Non-Coding RNA (lincRNAs)...
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- GASP1 enhances malignant phenotypes of breast cancer cells and decreases their response to...
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- Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify...
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- High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and...
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- Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR..
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- Regulation of rod photoreceptor function by farnesylated G-protein γ-subunits
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- Biased GPCR signaling by the native parathyroid hormone-related protein 1 to 141 relative to its...
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- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells...
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- GPR125 (ADGRA3) is an autocleavable adhesion GPCR that traffics with Dlg1 to the basolateral...
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- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
For this reason, DL models generally require more computational resources (such as powerful GPUs) and and their associations: open-access databases from experimental labs and new AI techniques will allow more regulatory bodies will likely increase in the coming years and will facilitate the creation of larger and more
- A new Kunitz-type snake toxin family associated with an original mode of interaction with the...
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- Co-activation of GPCRs facilitate GIRK-dependent current
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- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
The remaining non-sensory receptors, with functions more readily linked to pathology, are currently the interface for these GPCRs makes modulation with small molecule drugs, when they can be identified, much more Orion’s CCR2 antagonist analog (OB-004), discovered in only 6 months, is considerably more potent than and more central role for in silico methodology and AI in GPCR drug discovery. For more information, follow Orion Biotechnology on LinkedIn or visit www.orionbiotechnology.com.
- New role of β-arrestins in MOR signaling
EOPs): β-endorphin, enkephalins and dynorphins, and four opioid receptors (ORs): μ-opioid receptor (MOR Therefore to understand better the functions of arrestins in MOR signaling, Shiraki et al., explored the function of β-arrestin 2 in MOR signaling using the SH-SY5Y cell line that endogenously expresses MOR and was modified through CRISPR/Cas9 to knock out β-arrestin 1 and 2 gene expression. If you are interested in learning more about the molecular details of this study, you can consult the
- GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization...
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- Endothelin-1 Stimulates PAI-1 Protein Expression via Dual Transactivation Pathway Dependent ROCK...
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- Lack of Oestrogen Receptor Expression in Breast Cancer Cells Does Not Correlate with Kisspeptin...
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- Functional Characterization of the Venus Flytrap Domain of the Human TAS1R2 Sweet Taste Receptor
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- 📰 GPCR Weekly News
GPCR Binders, Drugs, and more Engineered Human Antibody with Improved Endothelin Receptor Type A Binding Reviews, GPCRs, and more Species dependence of A3 adenosine receptor pharmacology and function.
- Adhesion GPCR Consortium Newsletter - May 2024
adhesion molecules that also happened to be targeted by the same spider toxin as latrophilins, were a more As much as I was shocked that I wasn’t asked if I was a student or a PI, I was more proud to say that
- Role of G Protein-Coupled Receptors in Hepatic Stellate Cells and Approaches to Anti-Fibrotic ...
It is predicted that more than 50 GPCRs are expressed in the liver.
- Activation of GPR183 by 7 α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through...
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- Recurrent high-impact mutations at cognate structural positions in class A G protein-coupled ...
Because there are many more GPCRs than effectors, mutations in different receptors could perturb signaling
- 📰 GPCR Weekly News, January 30 to February 5, 2023
GPCR Binders, Drugs, and more Ligands selectively tune the local and global motions of neurotensin receptor Reviews, GPCRs, and more Understanding Neuropeptide Transmission in the Brain by Optical Uncaging and
- β2-Adrenergic Receptor Expression and Intracellular Signaling in B Cells Are Highly Dynamic during..
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