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  • GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP

    of PAR2 that induces unique cellular signaling, distinct from trypsin and PAR2-activating peptide (AP delayed and sustained manner compared to the rapid and transient signals induced by trypsin and PAR2-AP Interestingly, unlike PAR2-AP, GB83 and trypsin induced sustained receptor endocytosis and PAR2 colocalization

  • Applications of Fluorescent Probes in Confocal Imaging of GPCRs: From Live to Fixed Cells

    Applications of Fluorescent Probes in Confocal Imaging of GPCRs: From Live to Fixed Cells GPCRs are present Exploring the Applications of Confocal Fluorescence Microscopy in GPCR Research In GPCR research one Microscopy and spectroscopy approaches to study GPCR structure and function. Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application

  • Trevena Announce Submission of New Drug Application in China for OLINVYK® by its Partner Jiangsu ...

    February 2022 Trevena Announces Submission of New Drug Application in China for OLINVYK® by its Partner IV morphine, conducted in China by Nhwa Trevena is eligible to receive future success payments upon approval that China’s National Medical Products Administration (NMPA) has accepted submission of a New Drug Application of a Phase 3 bridging trial for OLINVYK (oliceridine) injection, a novel IV analgesic that has been approved

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