Search Results
268 items found for " Innate immunity"
Posts (163)
- Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin...
prevent skin dysbiosis and bacterial infection "Healthy skin maintains a diverse microbiome and a potent immune This signaling axis was required for effective neutrophil-mediated skin immunity and microbiome homeostasis combating S. aureus infections and the formation of neutrophil abscesses, a hallmark of antibacterial immunity release of IL-1β and CXCL2 which are vital for proper amplification and propagation of the antibacterial immune
- A central alarm system that gates multi-sensory innate threat cues to the amygdala
Previous findings suggest that parallel pathways independently relay innate threat signals from different Yet little is known about whether and how multi-sensory innate threat cues are integrated and conveyed The identification of unified innate threat pathways may provide insights into developing therapeutic candidates for innate fear-related disorders."
- C3aR plays both sides in regulating resistance to bacterial infections
bioactive C3a, a product of C3 cleavage, which interacts with membrane-bound receptor C3aR to regulate innate immune cell function and outcome of bacterial infection. research has identified mechanistically distinct and cell type–specific roles for C3aR in regulating innate immune cell inflammatory state, antimicrobial killing capacity, and metabolism.
Other Pages (105)
- The GPCR adaptor protein Norbin controls the trafficking of C5aR1 and CXCR4 in mouse neutrophils
< GPCR News < GPCRs in Oncology and Immunology The GPCR adaptor protein Norbin controls the trafficking the surface levels of the GPCRs C5aR1 and CXCR4 in neutrophils, and suppresses neutrophil-mediated innate immunity. Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology
- Session VIII | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
, Amsterdam institute for Immunology and Infectious diseases, Amsterdam University Medical Center, Amsterdam , The Netherlands; 3MS center ErasMS, Departments of Neurology and Immunology, Erasmus Medical Center , Rotterdam, The Netherlands" About Cheng-Chih Hsiao "2012-2015: PhD in Immunology, University of Amsterdam Institute of Innate Immunity, University Hospital Bonn, University of Bonn, 3. receptors impact cardiac structure and function, and has evolved to encompass their roles in regulating immune
- The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor
stimuli, including light, hormones, neurotransmitters, and odorants, some of which play critical roles in innate and adaptive immune responses. Here, we demonstrate that GPR141, an orphan GPCR belonging to the class A receptor family, suppresses immune Lymphocytes enriched from Gpr141 -/- mice immunized with myelin oligodendrocyte glycoprotein 35-55 produced These findings suggest that GPR141 functions as a negative regulator of immune responses by controlling