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166 items found for " Acute inflammation"

Posts (111)

  • Exendin-4 Attenuates Remodeling in the Remote Myocardium of Rats After an Acute Myocardial ...

    Exendin-4 Attenuates Remodeling in the Remote Myocardium of Rats After an Acute Myocardial Infarction Purpose: This study tested if the protective anti-remodeling effect of GLP-1 agonist Exendin-4 after an acute increased mRNA and protein levels of collagen I/III with higher levels of reactive oxygen species (ROS) and inflammatory Conclusion: Exendin-4 inhibits the remodeling in the remote myocardium of rats following acute MI by Β-catenin activation and nuclear translocation are associated with increased synthesis of inflammatory

  • In vivo metabolic effects after acute activation of skeletal muscle G s signaling

    Objective: The goal of this study was to determine the glucometabolic effects of acute activation of expressed by SKM at relatively high levels (β2-adrenergic receptor and CRF2 receptor) and studied the acute Results: Acute stimulation of GsD signaling in SKM impaired glucose tolerance in lean and obese mice The acute metabolic effects following agonist activation of β2-adrenergic and, potentially, CRF2 receptors The acute metabolic effects of UCN2 were not mediated by SKM Gs signaling.

  • Platelets in the NETworks interweaving inflammation and thrombosis

    chemokines and growth factors, which upon release may directly engage pathogens and/or contribute to inflammatory interplay between platelets and NETs and the potential of this alliance to influence the course of inflammatory

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Other Pages (55)

  • Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation

    disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation This was linked with an increased inflammatory response in the Gpr101 deficient animals and a reduced macrophage phenotype and function, modulating key biological activities in both limiting the propagation of inflammation Authors Magdalena B Flak , Duco S Koenis , Maria Gonzalez-Nunez , Ana Chopo-Pizarro , Jesmond Dalli Tags Acute inflammation , GPCR , Innate immunity , Macrophages , Resolution , Specialized pro-resolving mediators

  • Ep 134 with Dr. Neil Grimsey

    discovered a novel GPCR-dependent atypical kinase activation mechanism that drives vascular edema and inflammation My group studies the spatiotemporal dynamics of atypical inflammation and the control of disease progression atypical p38 signaling responses we are studying how atypical p38 controls the onset and pathogenesis of acute

  • Ep 134 with Dr. Neil Grimsey

    discovered a novel GPCR-dependent atypical kinase activation mechanism that drives vascular edema and inflammation My group studies the spatiotemporal dynamics of atypical inflammation and the control of disease progression atypical p38 signaling responses we are studying how atypical p38 controls the onset and pathogenesis of acute

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