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Despite major advances in the field of pharmacological CVD treatments, particularly in the field of heart failure (HF) research, case numbers and overall mortality remain high and have trended upwards over differential domains of GRK2 to modulate both beneficial and deleterious signaling pathways in the heart

events driving the fibrotic response and the communications between fibroblasts and other cells in the heart

October 2022 "Systolic heart failure (HF) is a chronic clinical syndrome characterized by the reduction alterations that confer significant hormonal burden on the already compromised function of the failing heart receptor antagonists, which block the effects of angiotensin II (AngII) and aldosterone on the failing heart

It turns out that it was signal transduction, and he worked on the signaling cascades involved in heart failure.

focus is on pulmonary arterial hypertension, a disease of the pulmonary arterioles that causes right heart failure, and he serves as co-director of the Duke Pulmonary Vascular Disease Center.

Bangalore, India, to investigate the mechanisms behind rare mitochondrial diseases, which can lead to heart failure, muscle fatigue, and neurodegenerative disorders.