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Hello GPCR Colleagues and Collaborators, We’re diving into May with serious momentum. This week brings sharp new insights into how minor changes in ligand structure can flip GPCR function, how ACKR3 modulates cardiac lymphatic repair, and how β-arrestins decode GPCR phosphorylation barcodes. Plus, check out the latest Dr. GPCR tools and key moves in the biotech world. Dr. GPCR Updates   We want your feedback - Help shape the future of Dr. GPCR.   Your voice matters. Every insight you share helps us build a smarter, more supportive GPCR community—together. Got a minute? Tell us what’s working and what’s missing .     Become a Dr. GPCR Ambassador - Share & refer with Dr. GPCR.   Help grow the GPCR community by joining the Dr. GPCR affiliate program. When someone signs up for a course, membership, or event through your referral link, you’ll receive a referral reward. It’s a simple way to share valuable resources and support the field—one connection at a time.   Join the Affiliate Program     Your Shortcut to Dr. GPCR University - A fast-reference guide for you!   The Dr. GPCR University Cheatsheet   is your quick-start guide to everything we offer—no downloads, no digging. Filter by topic, format, or access level to find exactly what you need to boost your GPCR knowledge.   Explore the Cheatsheet GPCR Publication Highlights   — Minimal Structural Variation of GPR84 Full Agonist Causes Functional Switch to Inverse Agonism   — ACKR3 Regulates the Cardiac Lymphatic Response After Ischemic Heart Injury.   — Phosphorylation “Barcodes” Tune β-arrestin Isoform Signaling via Allosteric Networks . Want the full breakdown? Explore this week’s research, tools, and biotech insights in one place. Collaboration is the catalyst—let’s redefine what’s possible in GPCR-driven therapeutics.    Best wishes, The Dr. GPCR Team

October 2022 Cholesterol-Dependent Dynamics of the Serotonin1A Receptor Utilizing Single Particle Tracking To explore the role of cholesterol in lateral dynamics of GPCRs, we utilized single particle tracking

To explore the role of cholesterol in lateral dynamics of GPCRs, we utilized single particle tracking

Patrick Sexton Dr. GPCR Podcast << Back to podcast list Dr. Patrick Sexton About Dr. Patrick Sexton Patrick Sexton is a Professor of Pharmacology, National Health and Medical Research Council Patrick Sexton on the web CCeMMP Monash University Dr.

Patrick Giguère Dr. Patrick Giguère Dr.

to animal models of disease Date & Time Friday, November 3rd / 11:05 AM Abstract Coming Soon About Patrick Sexton " Patrick Sexton is a NHMRC Senior Principal Research Fellow and Director, ARC Centre for Cryo-electron Sexton is also a co-founder of Septerna Inc. " Patrick Sexton on the web CCeMMP Monash University Dr.