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351 items found for " drug combination"

Programs (1)

  • GPCRs in Pharmacology

    provide an in-depth exploration of key concepts in pharmacology, offering a nuanced understanding of drug

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Posts (230)

  • Accelerating GPCR Drug Discovery With Conformation-Stabilizing VHHs

    GPCRs continue to be regarded as one of the most tractable classes of drug targets and are targeted by 30%–40% of current drugs (Hauser et al., 2017), with annual sales of GPCR-targeting drugs in 2018 accounting Despite this high number of GPCR targeted drugs, only a small portion (∼110) of the human GPCRome (consisting of approximately 850 GPCRs) has been successfully drugged, and obtaining highly potent and selective

  • Drug Discovery Picks Up the Pace, Stays on Target

    However, in drug discovery projects, perfection can’t be attained soon enough. A project to develop a perfect drug, or a drug that is as safe and effective as possible, may never begin If only Voltaire were here today to see how drug discovery is being accelerated by new technologies. Several new technologies that are being used to accelerate drug discovery are highlighted in this article screening, drug efficacy analyses, and toxicity studies; technologies that stabilize G protein–coupled

  • Function and structure of bradykinin receptor 2 for drug discovery

    provided molecular insights into the functions and regulation of B2R, which shed light on structure-based drug In this review, we summarize the structure and function of B2R in relation to drug discovery and discuss

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Other Pages (119)

  • Involvement of Protease-Activated Receptor2 Pleckstrin Homology Binding Domain in Ovarian Cancer: Expression in Fallopian Tubes and Drug Design

    Protease-Activated Receptor2 Pleckstrin Homology Binding Domain in Ovarian Cancer: Expression in Fallopian Tubes and Drug Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs

  • Ep 71 with Dr. Jean Martin Beaulieu

    research is aimed at understanding how cellular and molecular mechanisms regulated by psychoactive drugs In particular, D2R is the main pharmacological target of antipsychotic drugs prescribed for schizophrenia Work by the Beaulieu Lab has demonstrated that mood stabilizer drugs (e.g. lithium) used for bipolar mechanisms regulated by dopamine receptors, thus providing a framework to understand how different drug and drug development technology.

  • Interrogating Multiscale Receptors Functions in Space

    research is aimed at understanding how cellular and molecular mechanisms regulated by psychoactive drugs In particular, D2R is the main pharmacological target of antipsychotic drugs prescribed for schizophrenia Work by the Beaulieu Lab has demonstrated that mood stabilizer drugs (e.g. lithium) used for bipolar mechanisms regulated by dopamine receptors, thus providing a framework to understand how different drug and drug development technology.

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Events (1)

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