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26 items found for "Fibroblast"

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  • GPCRs and fibroblast heterogeneity in fibroblast-associated diseases

    < GPCR News < GPCRs in Oncology and Immunology GPCRs and fibroblast heterogeneity in fibroblast-associated Fibroblasts lay the architectural skeleton of the body, and play a key role in supporting the growth, Understanding the dynamics of GPCR signaling in fibroblasts with disease progression can help in the recognition of the complex interplay of different GPCR subtypes in fibroblast-mediated diseases. El-Kersh , Ruxana T Sadikot , Apar K Ganti , Surinder K Batra , Maneesh Jain Tags GPCR signaling , fibroblast

  • Single cell G-protein coupled receptor profiling of Transcription factor 21 expressing activated kidney fibroblasts

    Single cell G-protein coupled receptor profiling of Transcription factor 21 expressing activated kidney fibroblasts Published date April 28, 2023 Abstract " Background and purpose: Activated fibroblasts deposit fibrotic Here, we set out to establish a transcriptional profile that identifies activated kidney fibroblasts The adenosine receptors, Adora2a/2b were upregulated in Tcf21+ fibroblasts and the adenosine receptor Tags Adenosine receptor , Fibroblast , Fibrosis , GPCR , Kidney , Tcf21 .

  • Trainee Symposium I

    GPCR Title: Modeling Cardiac Fibrosis in a Dish: Combining hIPSC-Derived Fibroblasts and FRET Biosensors In my current research project I use iPSC-derived cardiac fibroblasts to examine cellular signaling in

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