Search Results
Results found for "IJzerman AP"
Posts (361)
- GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP
of PAR2 that induces unique cellular signaling, distinct from trypsin and PAR2-activating peptide (AP delayed and sustained manner compared to the rapid and transient signals induced by trypsin and PAR2-AP Interestingly, unlike PAR2-AP, GB83 and trypsin induced sustained receptor endocytosis and PAR2 colocalization
- Applications of Fluorescent Probes in Confocal Imaging of GPCRs: From Live to Fixed Cells
Applications of Fluorescent Probes in Confocal Imaging of GPCRs: From Live to Fixed Cells GPCRs are present Exploring the Applications of Confocal Fluorescence Microscopy in GPCR Research In GPCR research one Microscopy and spectroscopy approaches to study GPCR structure and function. Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application
- Trevena Announce Submission of New Drug Application in China for OLINVYK® by its Partner Jiangsu ...
February 2022 Trevena Announces Submission of New Drug Application in China for OLINVYK® by its Partner IV morphine, conducted in China by Nhwa Trevena is eligible to receive future success payments upon approval that China’s National Medical Products Administration (NMPA) has accepted submission of a New Drug Application of a Phase 3 bridging trial for OLINVYK (oliceridine) injection, a novel IV analgesic that has been approved
Other Pages (247)
- Dr. Alix A. J. Rouault | Dr. GPCR Ecosystem
Further, I applied to create a scientific session at the American Physiology Summit (APS) 2024 dedicated Our session was picked up by the APS. It takes <60 seconds and makes a big difference. ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send
- 10 GPCR pharmacology lessons. Zero fluff. Launching July 1, Terry’s Corner gives you the clarity and confidence to make better decisions—starting with: • The role of pharmacology in discovery strategy • Black & Leff’s operational model—finally made practical • Binding curves, orthosteric vs allosteric function, and real vs apparent affinity • Molecular dynamics and how they guide ligand design • Why Terry built this—and how it sharpens your next move 📅 Learn anytime. New course every week. 📬 Subscribe to The Kenakin Brief → https://www.terrykenakin.com #GPCRscience #drugdiscovery #TerrysCorner #GPCRpharmacology #ligandbinding | Dr. GPCR Ecosystem
operational model—finally made practical • Binding curves, orthosteric vs allosteric function, and real vs apparent operational model—finally made practical 🟢 Binding curves, orthosteric vs allosteric function, and real vs apparent
- 🚀 New Workshop: Practical Quantification of Allosteric Modulation Join Dr. Terry Kenakin on May 1st, 2025, for an advanced live workshop on allosteric modulators in GPCR drug discovery. Learn how to: ✔️ Identify, measure, and quantify allosteric properties ✔️ Apply functional allosteric models to determine mechanisms of action ✔️ Confirm allostery through kinetic analysis 📅 Date: May 1st, 2025 ⏳ Registration deadline: April 18th 📍 Live on Google Meet 🔗 Register now: https://www.ecosystem.drgpcr.com/event-details-registration/practical-quantification-of-allosteric-modulation #GPCR #Allostery #DrugDiscovery #Pharmacology | Dr. GPCR Ecosystem
Learn how to: ✔️ Identify, measure, and quantify allosteric properties ✔️ Apply functional allosteric action ✔️ Confirm allostery through kinetic analysis 📅 Date: May 1st, 2025 ⏳ Registration deadline: April Learn how to: ✔️ Identify, measure, and quantify allosteric properties✔️ Apply functional allosteric action✔️ Confirm allostery through kinetic analysis 📅 Date: May 1st, 2025⏳ Registration deadline: April
Events (2)
- October 2, 2025 | 2:00 PM
- Practical Quantification of Allosteric ModulationTickets: $0.00May 1, 2025 | 2:00 PM
