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1 item found for "Tcf21"

  • Single cell G-protein coupled receptor profiling of Transcription factor 21 expressing activated kidney fibroblasts

    Key results: Transcription factor 21 (Tcf21)+ cells that expressed 2 or 3 of Postn, Acta2 and Pdgfra Tcf21+ α-smooth muscle actin (α-SMA)+ interstitial cells accumulated in the kidneys of mice with UUO The adenosine receptors, Adora2a/2b were upregulated in Tcf21+ fibroblasts and the adenosine receptor antagonist, caffeine decreased Tcf21 upregulation and kidney fibrosis in UUO mice. Tags Adenosine receptor , Fibroblast , Fibrosis , GPCR , Kidney , Tcf21 .