Dopamine-Mediated Motor Recovery after Ischemic Stroke

About Mario Tiberi

"I did my graduate research on the regulation of axonal transport by tricyclic antidepressants (M.Sc.) and molecular pharmacology of opioid receptors (Ph.D.) in the Department of Pharmacology at the Université de Montréal under the mentorship of Dr. Pierre-André Lavoie and Dr. Jacques Magnan, respectively. I then pursued my postdoctoral training at Duke University in the laboratory of Dr. Marc Caron, where I cloned the dopamine D5 receptor gene and investigated the regulation of dopaminergic and adrenergic receptors. My addiction for dopamine led me to the Ottawa Hospital Research Institute (then the Moses and Rose Loeb Research Institute) to develop my independent research program.

The Tiberi Lab pursues the study of the molecular, structural, pharmacological and signaling features of dopamine (DA) receptors. We are also currently developing the translational component of our research to capitalize on the druggability potential of GPCRs. More specifically, we investigate the druggability potential of new signaling partners we identified that drive the formation of different DA receptor complexes. We hope our research will aid in the development of new therapeutic interventions for the alleviation of L-DOPA-induced dyskinesia in Parkinson’s Disease and improvement of post-stroke recovery."

Mario Tiberi on the web

• University of Ottawa

• Pubmed

• Google Scholar

• ResearchGate

• LinkedIn

• Dr. GPCR