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GPCR Retreat Program

Thursday, November 2nd / 11:00 AM - 1:30 PM

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Registration

Thursday, November 2nd / 1:30 PM

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Welcome Remarks

Thursday, November 2nd / 1:45 PM - 2:45 PM

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Trainee Symposium I

  • Eric Johansen, Johns Hopkins University

  • Grace Mazarura, McGill University

  • Émile Breault, Université de Sherbrooke

  • Bassam Albraidy, Ottawa Hospital Research Institute

Thursday, November 2nd / 2:45 PM

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Coffee Break 1

Thursday, November 2nd / 3:00 PM - 4:00 PM

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Trainee Symposium II

  • Amr Mousa, University of Western Ontario

  • Louis-Philippe Picard, University of Toronto

  • Remi Janicot, Boston University

  • Meredith Skiba, Harvard University

Thursday, November 2nd / 4:00 PM

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Check In

Thursday, November 2nd / 4:30 PM

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"Have a nice weekend, and I'll see you tomorrow!": RAMP-interacting GPCR Pathways

Inaugural Marc G. Caron Keynote Lecture

Kathleen M. Caron

University of North Carolina at Chapel Hill

Thursday, November 2nd / 5:30 PM

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Welcome Reception and Poster Session 1

Thursday, November 2nd / 8:00 PM

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Dinner 1

Friday, November 3rd / 7:30 AM

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Breakfast 1


Friday, November 3rd / 8:30 AM

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Dopamine-Mediated Motor Recovery after Ischemic Stroke

Mario Tiberi

Ottawa Hospital Research Institute

Friday, November 3rd / 8:55 AM

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A journey from Duke to McGill along the dopamine circuit

Bruno Giros

McGill University

Friday, November 3rd / 9:20 AM

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Cannabinoid compounds to augment L-DOPA treatment in Parkinson's Disease

Ali Salahpour

University of Toronto

Friday, November 3rd / 9:45 AM

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Pharmacological and Genetic Preclinical Models of Ghrelin Receptor Functional Selectivity to Investigate Metabolic Disease Pathophysiology

Joshua Gross

Duke University Medical Center

Friday, November 3rd / 10:25 AM

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Coffee Break 3

Friday, November 3rd / 10:40 AM

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Regulation and role of mitochondria delta opioid receptors

Louis Gendron

Université de Sherbrooke

Friday, November 3rd / 11:05 AM

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Biased agonism at the GLP-1 receptor: from structure to animal models of disease

Patrick Sexton

Monash University

Friday, November 3rd / 11:30 AM

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Complex Allosteric Cannabinoid Receptor Pharmacology

Robert Laprairie

University of Saskatchewan

Friday, November 3rd / 11:55 AM

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Unveiling Non-Canonical Functions for Gαq Signaling Pathways

Poster Talk

Catalina Ribas

University Autonoma of Madrid

Friday, November 3rd / 12:10 PM

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Lunch 1

Friday, November 3rd / 1:30 PM

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Interaction with the cell adhesion molecule NEGR1 affects mGluR5 cell signalling

Fabiola Ribeiro

Federal University of Minas Gerais, Brazil

Friday, November 3rd / 1:55 PM

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A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice

Khaled Abdelrahman

The University of British Columbia

Friday, November 3rd / 2:10 PM

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Genetic Deletion of Atypical VGLUT3 Rescues Huntington’s Disease Phenotype
and Neurodegeneration in zQ175 Mice

Poster Talk

Karim Ibrahim

University of Ottawa

Friday, November 3rd / 2:45 PM

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Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity

Heidi Hamm

Vanderbilt University

Friday, November 3rd / 3:00 PM

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Coffee Break 4

Friday, November 3rd / 3:30 PM

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G Proteins and GPCRs in Cancer: Novel Precision Targeted and Immunotherapies

J. Silvio Gutkind

UC San Diego

Friday, November 3rd / 3:55 PM

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Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in
Ovarian Cancer

Robert Rottapel

University of Toronto

Friday, November 3rd / 4:20 PM

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Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal
Melanoma

Poster Talk

Victoria Rasmussen

Rockefeller University

Friday, November 3rd / 4:35 PM

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Targeting adenosine signaling for immuno-oncology

John Stagg

CHUM, Université de Montréal

Friday, November 3rd / 5:00 PM

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Poster Session #2

Friday, November 3rd / 7:00 PM

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Dinner 2

Friday, November 3rd / 9:30 PM

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Board Meeting

To discuss the next GPCR Retreat

All PIs welcome

Saturday, November 4th / 7:30 AM

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Breakfast 2

Saturday, November 4th / 8:15 AM

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Distinct sub-cellular signal propagation as a component of functional selectivity

Saturday, November 4th / 8:40 AM

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Biochemical Mechanisms Underlying Location Bias in GPCR Signaling

Sudarshan Rajagopal

Duke University Medical Center

Saturday, November 4th / 9:05 AM

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Structure-based discovery of functionally selective 5-HT1A receptor agonists

Peter Gmeiner

Friedrich-Alexander University of Erlangen-Nürnberg

Saturday, November 4th / 9:30 AM

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Atypical Structure and Function of Typical Chemokine Receptors

Tracy Handel

UC San Diego

Saturday, November 4th / 9:55 AM

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Coffee Break 5

Saturday, November 4th / 10:10 AM

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Using food perception and bioamine signaling networks to slow aging

Scott Leiser

University of Michigan

Saturday, November 4th / 10:35 AM

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Interrogating Multiscale Receptors Functions in Space

Martin Beaulieu

University of Toronto

Saturday, November 4th / 11:00 AM

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Atypical Structure and Function of Typical Chemokine Receptors

Amy Ramsey

University of Toronto

Saturday, November 4th / 11:30 AM

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Illuminating Functional Selectivity and Allosterism at GPCRs.

Hyman B. Niznik Keynote Lecture

Stephane Laporte

McGill University

Saturday, November 4th / 12:30 PM

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Closing Remarks. Lunch and farewell

Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec

Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec


22nd GPCR Retreat Sponsored by


 

Canada Research Chairs
U of Ottawa
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Bristol Myers Squibb
InversAgo Pharma
Monica Seger and Family
Duke University, Dept. Cell Biology
OHRI Neurosciences Program
University of Toronto Mississauga
Domain Therapeutics NA Inc.
Otsuka Pharmaceuticals
McGill University, Dept. Pharmacol & Exp Ther
University of Toronto, Dept. of Physiology
Hotchkiss Brain Institute,University of Calgary
OHRI
Université de Montréal, VP Office
Find Therapeutics
University of Toronto, Dept. Pharmacol & Toxicol
Deep Apple
University of Illinois at Chicago (Mark Rasenick)
uOttawa, VP Research Office
American Society of Pharmacology and Experimental Therapeutics
University of Western Ontario Schulich School of Medicine & Dentistry
Heliyon
Université de Sherbrooke, Dept. Pharmacology-Physiology
Research Institute McGill Univ. Health Centre
adMare Bioinnovations
Superluminal
Université de Montréal, Faculty of Medicine
Université de Sherbrooke, Institut de Pharmacologie
Science Signaling
Montana Molecular
IRIC
uOttawa, Dept. Cellular & Molecular Medicine
uOttawa, Dept. Biochem Microbiol Immunol
uOttawa, Behavioral & Physiology Core
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