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472 results found for "Stefano Moro"
- Dual loss of regulator of G protein signaling 2 and 5 exacerbates ventricular myocyte arrhythmias...
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- Structural view of G protein-coupled receptor signaling in the retinal rod outer segment
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- Mechanism of enhanced sensitivity of mutated β-adrenergic-like octopamine receptor to amitraz in...
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- G protein-coupled receptor signaling: transducers and effectors
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- Cancer Research UK and Sosei Heptares sign agreement to advance cancer immunotherapy candidate ...
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- G protein-coupled receptor kinase type 2 and β-arrestin2: Key players in immune cell functions...
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- GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by β-arrestin recruiting
in human neutrophils and analysis of subcellular fractions revealed a cytosolic localization. " Read more
- Emerging approaches for decoding neuropeptide transmission
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- 📰 GPCR Weekly News, March 25 to March 31, 2024
Stay tuned for more updates. for exploration of GLP-1R ligand effects in pancreatic β-cells and neurons GPCR Binders, Drugs, and more Monitoring norepinephrine release in vivo using next-generation GRABNE sensors Reviews, GPCRs, and more
- 📰 GPCR Weekly News, October 23 to 29, 2023
distinct β-arrestin 2-dependent pathways to regulate pancreatic β cell function GPCR Binders, Drugs, and more ThermoBRET: A Ligand-Engagement Nanoscale Thermostability Assay Applied to GPCRs Reviews, GPCRs, and more
- Jan Steyaert Named 2022 Jacob and Louise Gabbay Award Winner
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- Dr. Mark Connor - Dr. GPCR Podcast
Learn more about #GPCRs and life as an academic wearing different hats.
- Trevena Announces Receipt of First $15 million Tranche in Connection with its $40 million ...
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- Applying Allosteric Modulator Pharmacology to Treat Dyskinesia and Other Movement Disorders with ...
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- Third Rock pushes newest fund over $1B line as it marks 15 years in venture capital
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- Michel Bouvier appointed Knight of the Ordre national du Québec
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- Trevena Announces Advancement of TRV045 Into Clinical Development for Diabetic Neuropathic Pain
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- Sosei Heptares Announces Antitrust Clearance of License Agreement with Neurocrine Biosciences
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- Unveiling GPCR Priming: The Hidden Synergy in Cellular Signalling
priming is attributed to the formation of temporal non-cognate-GPCR conformational states, which enable more It challenges the traditional view of strict cognate G protein coupling and suggests a more dynamic interaction
- 📰 GPCR Weekly News
Hello Readers👋, We are working on bringing your the latest GPCR News more frequently directly in your GPCR Binders, Drugs, and more Altered signaling at the PTH receptor via modified agonist contacts with Reviews, GPCRs, and more The diversity of invertebrate visual opsins spanning Protostomia, Deuterostomia
- Single-molecule counting applied to the study of GPCR oligomerization
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- Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
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- Developing the Cannabinoid Receptor 2 (CB2) pharmacopoeia: past, present, and future
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- GPCR Therapeutics Expands Scientific Advisory Board
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- Domain Therapeutics Raises $42m Series A Financing
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- Inversago Pharma Completes Phase 1 Clinical Trial on First-in-Class, Peripheral CB1 Blocker and...
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- Developing the Cannabinoid Receptor 2 (CB2) pharmacopeia: past, present, and future
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- Targeting Intracellular Allosteric Sites in GPCRs
This allows for the fine-tuning of receptor activity, leading to more specific and safer drugs. Allosteric modulators targeting GPCRs can display one or more of the following pharmacological characteristics Advantages of targeting GPCRs allosteric sites Allosteric sites offer a more nuanced approach to modulating
