This comprehensive course is designed to provide an in-depth exploration of key concepts in pharmacology, offering a nuanced understanding of drug interactions and mechanisms of action. The curriculum is divided into four modules, each focusing on essential aspects of pharmacological principles. Whether you are a healthcare professional, researcher, or student in the life sciences, this course will enhance your knowledge and critical thinking skills in the field of pharmacology.

GPCR Ecosystem.

GPCR Ecosystem.

G protein-coupled receptors (GPCRs) are among the most promising drug targets. Specifically controlling the activity of GPCR dimers with ligands is a good approach to clarify their This region corresponds to the sodium ion binding site in class A GPCRs that controls the basal state reveal the possibility of developing allosteric compounds able to specifically modulate the activity of GPCR

A G-protein coupled receptors (GPCRs) through a conserved binding site, not present in class B GPCRs For class B GPCRs, previous molecular dynamics (MD) simulation studies have shown PI(4,5)P2 interacting Interestingly, we find that in contrast to class A GPCRs, PI(4,5)P2 appear to stabilize the inactive conformation of GCGR through a binding site conserved across class B GPCRs but absent in class A GPCRs This suggests differences in the regulatory function of PI(4,5)P2 between class A and class B GPCRs."

sweet taste receptor is a heterodimeric receptor composed of two distinct G-protein-coupled receptors (GPCRs The TAS1R2 and TAS1R3 subunits are members of a small family of class C GPCRs whose members share the Read more at the source #DrGPCR #GPCR #IndustryNews

GPCR Podcast << Back to podcast list Dr. After her Ph.D., she moved to Australia and continues working on GPCRs. Her current research focuses on class B GPCRs and understanding how GPCR signaling and function is mediated Join me to learn more about Elva, class B GPCRs, and Tilly. Dr. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand

GPCR Podcast << Back to podcast list Dr. Hannes Schihada About Dr. My project involved the development of FRET/BRET -based GPCR conformational biosensors, which can be Frizzled GPCR s in the lab of Gunnar Schulte at the Karolinska Institute. A GPCRs , GPR3 , GPR6 , and GPR12 . GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand

GPCR Podcast << Back to podcast list Dr. Qing Fan About this episode Dr. Qing is a structural biologist interested in the molecular mechanisms controlling how class C GPCRs transmit GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand