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  • Illuminating GPCR Research: FRET and BRET-Based Sensors Shed Light on Cellular Signaling

    G protein-coupled receptors (GPCRs) are integral membrane proteins crucial for sensing extracellular Central to GPCR function are G proteins, comprising subfamilies such as Gs, Gi/o, Gq/11, and G12/13, Despite their immense potential, utilizing FRET and BRET sensors in GPCR research comes with challenges In conclusion, FRET and BRET-based sensors have transformed the landscape of GPCR research, offering unprecedented insights into the intricacies of GPCR signaling.

  • β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the...

    β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR cells "β-arrestins mediate regulatory processes for over 800 different G protein-coupled receptors (GPCRs ) by adopting specific conformations that result from the geometry of the GPCR-β-arrestin complex. However, whether β-arrestin1 and 2 respond differently for binding to the same GPCR is still unknown. Read more at the source #DrGPCR #GPCR #IndustryNews Subscribe to the Dr. GPCR Newsletter

  • Cholesterol-Dependent Dynamics of the Serotonin1A Receptor Utilizing Single Particle Tracking: ...

    Receptor Utilizing Single Particle Tracking: Analysis of Diffusion Modes "G protein-coupled receptors (GPCRs Serotonin1A receptors are important members of the GPCR family and are implicated in neuropsychiatric To explore the role of cholesterol in lateral dynamics of GPCRs, we utilized single particle tracking results bring out the interdependence of cholesterol and actin cytoskeleton in regulating diffusion of GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews

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  • GPCR Retreat Logo Contest | Dr. GPCR Ecosystem

    Retreat Logo Contest In anticipation of the next GPCR Retreat, we are delighted to announce the GPCR This competition invites creative minds to make a captivating logo representing the essence of GPCR research GPCRs play critical roles in many physiological processes, making them a focal point of scientific research research, such as biochemistry, pharmacology, structural biology, and translational medicine. Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

  • 23-10 Dr GPCR Newsletter

    GPCR Program that will provide courses and content on GPCR research to support our community. Logo Contest , a competition that invites creative minds to represent the essence of GPCR research, Calling all creative minds to capture the essence of GPCR research, collaboration, and scientific brilliance Take a look at the latest news classified by topic: Adhesion GPCRs GPCR Activation and Signaling GPCR and Molecular Insights into GPCR Function Industry News Call for GPCR Papers GPCR Events, Meetings,

  • AGPCR 24 Newsletter | Dr. GPCR Ecosystem

    We've got 15 insightful GPCR research papers and updates... We have a total of 34 insightful GPCR research papers and... Select Adhesion GPCR Workshop 2024 One Year Dr. Select Adhesion GPCR Workshop 2024 One Year Dr. Up Abstract Submission Submit your research abstracts following our guidelines to present at the conference

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