Thomas P. Sakmar

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37 items found for "Thomas P. Sakmar"

Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Authors Peter J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice
Ovarian cancer G protein-coupled receptor 1 (OGR1) deficiency exacerbates crystal deposition and kidney injury in oxalate nephropathy in female mice
</p> Taken together, in the acute setting of oxalate-induced nephropathy, the lack of the proton-activated
Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
Authors Kathrine Lundø , Oksana Dmytriyeva , Louise Spøhr , Eliana Goncalves-Alves , Jiayi Yao , Laia P
Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
characteristics of growth hormone (GH)-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors (GHomas the genetic alterations, protein expression profiles, transcriptomes, and clinical characteristics of GHomas genes and nontargeted proteomics analysis were performed on fresh-frozen samples from 121 sporadic GHomas
Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
Subsequent permutation analysis can define the protein regions that are most significantly intolerant ( P
21-06 Dr GPCR Newsletter
the MC4 receptor to initiate satiation signaling Selective G protein signaling driven by Substance P-Neurokinin
21-10 Dr GPCR Newsletter
Aaron Sato presented last month at Biorender's Visualize 2021 Montana Molecular's CSO, Thomas Hughes
20-12 Dr GPCR Newsletter
Histamine Receptor Subtypes Statistics for the analysis of molecular dynamics simulations: providing P
21-02 Dr GPCR Newsletter
Characterization of GPCR Activity and Function during Endosomal Trafficking Pathway Gβγ recruits and activates P-Rex1