GPCR News

Kiyan Afzali

Mar 1011 min read

319

Reflections on My PhD Journey: Lessons Learned

Nov 26, 20243 min read

Harnessing Deep Mutational Scanning for Enhanced Drug Discovery

Nov 12, 20244 min read

100

Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling

Oct 29, 20243 min read

116

Profiling Immune Cell and Platelet Transcriptomes

Oct 22, 20242 min read

Targeted Drug Design through GPCR Mutagenesis: Insights from β2AR

Oct 8, 20243 min read

130

AlphaFold’s Breakthrough in GPCR Research: Revolutionizing Discovery, Yet Awaiting Experimental Proof

Ya-Tzu Li

Oct 1, 20242 min read

121

Biased Agonism at the GLP-1 Receptor: A Pathway to Improved Therapeutic Outcomes

Sep 23, 20244 min read

193

APEX2/AUR Biosensor: A Powerful Tool for Protein Interaction and Trafficking

Sep 10, 20242 min read

Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery

Sep 3, 20244 min read

149

Do You Believe AI Could Accelerate Drug Discovery?

Ya-Tzu Li

Jun 25, 20243 min read

Unveiling GPCR Priming: The Hidden Synergy in Cellular Signalling

Jun 18, 20243 min read

160

Navigating the Signaling Network: RTK and GPCR Crosstalk Uncovered

Jun 11, 20243 min read

137

Canonical chemokine receptors as scavenging “decoys”

Jun 4, 20242 min read

Extracellular signal-regulated kinases – a potential pathway for GPCR-targeted drug discovery

May 28, 20243 min read

137

Dynamic GPCR activation revealed through time-resolved Cryo-EM

Ya-Tzu Li

May 21, 20243 min read

234

Illuminating GPCR Research: FRET and BRET-Based Sensors Shed Light on Cellular Signaling

May 14, 20244 min read

262

From DNA day to GPCR genomics

Apr 16, 20244 min read

GPCRs are not simple on-off switches: deep dive into GPCR-ligand interactions

Apr 2, 20245 min read

287

An overview of the compartmentalized GPCR Signaling: Relevance and Implications

Mar 5, 20245 min read

214

Chemokine receptor-targeted drug discovery: progress and challenges

Jan 9, 20244 min read

222

Targeting Intracellular Allosteric Sites in GPCRs

Nov 1, 20234 min read

245

Nanobodies: New Dimensions in GPCR Signaling Research

Sep 26, 20234 min read

146

Decoding β-Arrestins: from Structure to function