GPCR NewsOct 1, 20221 minGPCRs in Oncology and ImmunologyEnhanced membrane binding of oncogenic G protein αqQ209L confers resistance to inhibitor YM-254890October 2022 "Heterotrimeric G proteins couple activated G protein-coupled receptors (GPCR) to intracellular signaling pathways. They can...
GPCR NewsSep 1, 20221 minStructural and Molecular InsightsIsoforms of GPR35 have distinct extracellular N-termini that allosterically modify...September 2022 Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and...
GPCR NewsSep 1, 20221 minStructural and Molecular InsightsIntegrative model of the FSH receptor reveals the structural role of the flexible hinge regionSeptember 2022 "The follicle-stimulating hormone receptor (FSHR) belongs to the glycoprotein hormone receptors, a subfamily of...
GPCR NewsDec 29, 20211 minGPCRs in Oncology and ImmunologyCharacterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of ...Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of the chemokine receptor CXCR4 WHIM...