Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex
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October 2022 "Arrestins interact with G protein-coupled receptors (GPCRs) to stop G protein activation and to initiate key signaling...
GPCR News
- Oct 1, 2022
- 1 min
Mechanism of enhanced sensitivity of mutated β-adrenergic-like octopamine receptor to amitraz in...
October 2022 Mechanism of enhanced sensitivity of mutated β-adrenergic-like octopamine receptor to amitraz in honeybee Apis mellifera: An...
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GPCR News
- Aug 1, 2022
- 1 min
GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin...
August 2022 GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors "Serotonin (or...
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GPCR News
- Aug 1, 2022
- 1 min
Fusion protein strategies for cryo-EM study of G protein-coupled receptors
August 2022 "Single particle cryogenic-electron microscopy (cryo-EM) is used extensively to determine structures of activated G...
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GPCR News
- Aug 1, 2022
- 1 min
Structures of β 1-adrenergic receptor in complex with Gs and ligands of different efficacies
August 2022 "G-protein-coupled receptors (GPCRs) receive signals from ligands with different efficacies, and transduce to heterotrimeric...
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GPCR News
- Aug 1, 2022
- 1 min
Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5...
August 2022 "G-protein-coupled receptors (GPCR) are present at the cell surface in different conformational and oligomeric states....
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GPCR News
- Aug 1, 2022
- 1 min
Helix 8 in chemotactic receptors of the complement system
August 2022 "Host response to infection involves the activation of the complement system leading to the production of anaphylatoxins C3a...
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GPCR News
- Aug 1, 2022
- 1 min
Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response
August 2022 "Oxysterols induce the migration of B-lymphocytes and dendritic cells to interfollicular regions of lymphoid tissues through...
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GPCR News
- Aug 1, 2022
- 1 min
Nuclear localization of histamine receptor 2 in primary human lymphatic endothelial cells
August 2022 "Histamine exerts its physiological functions through its four receptor subtypes. In this work, we report the subcellular...
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