Dual loss of regulator of G protein signaling 2 and 5 exacerbates ventricular myocyte arrhythmias...
October 2022 Dual loss of regulator of G protein signaling 2 and 5 exacerbates ventricular myocyte arrhythmias and disrupts the...
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GPCR News
Sep 30, 20221 min read
Structural view of G protein-coupled receptor signaling in the retinal rod outer segment
October 2022 "Visual phototransduction is the most extensively studied G protein-coupled receptor (GPCR) signaling pathway because of its...
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GPCR News
Sep 30, 20221 min read
Intermolecular Interactions in G Protein-Coupled Receptor Allosteric Sites at the Membrane Interface
October 2022 Intermolecular Interactions in G Protein-Coupled Receptor Allosteric Sites at the Membrane Interface from Molecular Dynamics...
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GPCR News
Sep 30, 20222 min read
Activation of GPR183 by 7 α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through...
October 2022 Activation of GPR183 by 7 α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through Mitogen-Activated Protein...
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GPCR News
Sep 30, 20221 min read
Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C...
October 2022 Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C isozymes are involved in...
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GPCR News
Sep 30, 20221 min read
Function and structure of bradykinin receptor 2 for drug discovery
October 2022 "Type 2 bradykinin receptor (B2R) is an essential G protein-coupled receptor (GPCR) that regulates the cardiovascular system...
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GPCR News
Sep 30, 20221 min read
Differences across sexes on head-twitch behavior and 5-HT2A receptor signaling in C57BL/6J mice
October 2022 "Psychedelics, also known as classical hallucinogens, affect processes related to perception, cognition and sensory...
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GPCR News
Sep 30, 20221 min read
Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
October 2022 "Recently determined structures of class C G protein-coupled receptors (GPCRs) revealed the location of allosteric binding...
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GPCR News
Sep 30, 20221 min read
Single-molecule counting applied to the study of GPCR oligomerization
October 2022 "Single-molecule counting techniques enable a precise determination of the intracellular abundance and stoichiometry of...
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GPCR News
Sep 30, 20221 min read
A cryptic mode of GPCR regulation revealed
October 2022 "Over three decades of research have provided thorough insights into G protein-coupled receptor (GPCR) regulation. In a...
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GPCR News
Aug 31, 20221 min read
Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epith
September 2022 Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epithelium That Directs...
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GPCR News
Aug 31, 20221 min read
Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify...
September 2022 Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and...
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GPCR News
Aug 31, 20221 min read
Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells...
September 2022 Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted...
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GPCR News
Dec 28, 20212 min read
Self-docking and cross-docking simulations of G protein-coupled receptor-ligand complexes
Self-docking and cross-docking simulations of G protein-coupled receptor-ligand complexes: Impact of ligand type and receptor activation...
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GPCR News
Dec 13, 20211 min read
GPCRs Are Optimal Regulators of Complex Biological Systems and Orchestrate the Interface between ...
GPCRs Are Optimal Regulators of Complex Biological Systems and Orchestrate the Interface between Health and Disease GPCRs arguably...
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GPCR News
Dec 9, 20211 min read
G protein-coupled receptor interactions and modification of signalling involving the ghrelin ...
G protein-coupled receptor interactions and modification of signalling involving the ghrelin receptor, GHSR1a The growth hormone...
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GPCR News
Dec 3, 20211 min read
Integration and Spatial Organization of Signaling by G Protein-Coupled Receptor Homo- and ...
Integration and Spatial Organization of Signaling by G Protein-Coupled Receptor Homo- and Heterodimer Information flow from a source to a...
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GPCR News
Nov 1, 20211 min read
Genome-wide identification of 216 G protein-coupled receptor (GPCR) genes from the marine water ...
Genome-wide identification of 216 G protein-coupled receptor (GPCR) genes from the marine water flea Diaphanosoma celebensis G...
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