top of page
Blog: Blog2
GPCR News
Search

Kiyan Afzali
Mar 1011 min read
The Perils and Guardrails of Modifying Signalling Proteins in Bioassays
Dr. Kiyan Afzali  ‘What we observe is not nature itself, but nature exposed to our method of questioning.’ –Werner Heisenberg 1....
129 views
0 comments
GPCR News
Oct 1, 20221 min read
β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the...
October 2022 β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells...
63 views
0 comments
GPCR News
Oct 1, 20221 min read
Single-molecule counting applied to the study of GPCR oligomerization
October 2022 "Single-molecule counting techniques enable a precise determination of the intracellular abundance and stoichiometry of...
3 views
0 comments
GPCR News
Oct 1, 20221 min read
Cholesterol-Dependent Dynamics of the Serotonin1A Receptor Utilizing Single Particle Tracking: ...
October 2022 Cholesterol-Dependent Dynamics of the Serotonin1A Receptor Utilizing Single Particle Tracking: Analysis of Diffusion Modes...
6 views
0 comments
GPCR News
Oct 1, 20221 min read
Bell-Evans model and steered molecular dynamics in uncovering the dissociation kinetics of ligands..
October 2022 Bell-Evans model and steered molecular dynamics in uncovering the dissociation kinetics of ligands targeting...
4 views
0 comments
GPCR News
Aug 1, 20221 min read
Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence...
August 2022 Production of human A 2A AR in lipid nanodiscs for 19 F-NMR and single-molecule fluorescence spectroscopy "We describe...
3 views
0 comments
GPCR News
Aug 1, 20221 min read
In vivo detection of GPCR-dependent signaling using fiber photometry and FRET-based biosensors
August 2022 "Genetically encoded fluorescent biosensors allow intracellular signaling dynamics to be tracked in live cells and tissues...
3 views
0 comments
GPCR News
Aug 1, 20221 min read
Luciferase-based GloSensorâ„¢ cAMP assay: Temperature optimization and application to cell-based kinet
August 2022 Luciferase-based GloSensorâ„¢ cAMP assay: Temperature optimization and application to cell-based kinetic studies "G...
2 views
0 comments
GPCR News
Aug 1, 20221 min read
A NanoBRET-Based H 3 R Conformational Biosensor to Study Real-Time H 3 Receptor Pharmacology in...
August 2022 A NanoBRET-Based H 3 R Conformational Biosensor to Study Real-Time H 3 Receptor Pharmacology in Cell Membranes and Living...
5 views
0 comments
bottom of page