Blog: Blog2

GPCR News

Sep 30, 20221 min read

β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the...

October 2022 β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells...

Sep 30, 20221 min read

Single-molecule counting applied to the study of GPCR oligomerization

October 2022 "Single-molecule counting techniques enable a precise determination of the intracellular abundance and stoichiometry of...

Sep 30, 20221 min read

Cholesterol-Dependent Dynamics of the Serotonin1A Receptor Utilizing Single Particle Tracking: ...

October 2022 Cholesterol-Dependent Dynamics of the Serotonin1A Receptor Utilizing Single Particle Tracking: Analysis of Diffusion Modes...

Sep 30, 20221 min read

Bell-Evans model and steered molecular dynamics in uncovering the dissociation kinetics of ligands..

October 2022 Bell-Evans model and steered molecular dynamics in uncovering the dissociation kinetics of ligands targeting...

Jul 31, 20221 min read

Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence...

August 2022 Production of human A 2A AR in lipid nanodiscs for 19 F-NMR and single-molecule fluorescence spectroscopy "We describe...

Jul 31, 20221 min read

In vivo detection of GPCR-dependent signaling using fiber photometry and FRET-based biosensors

August 2022 "Genetically encoded fluorescent biosensors allow intracellular signaling dynamics to be tracked in live cells and tissues...

Jul 31, 20221 min read

Luciferase-based GloSensor™ cAMP assay: Temperature optimization and application to cell-based kinet

August 2022 Luciferase-based GloSensor™ cAMP assay: Temperature optimization and application to cell-based kinetic studies "G...

Jul 31, 20221 min read

A NanoBRET-Based H 3 R Conformational Biosensor to Study Real-Time H 3 Receptor Pharmacology in...

August 2022 A NanoBRET-Based H 3 R Conformational Biosensor to Study Real-Time H 3 Receptor Pharmacology in Cell Membranes and Living...