Insights That Move the GPCR Field Forward

Calcium mobilization is one of the fastest and most sensitive ways to measure GPCR activation, but no single readout fits every question. This article walks through how calcium assays work, compares dye-based, aequorin, and genetically encoded detection approaches, and shows how to match the right cell model and assay format to your drug discovery goals.

Spring break at Dr. GPCR — five live Masterclasses scheduled before summer break, examining GPCR science past the equilibrium snapshot. From signaling kinetics to program building, plus two recordings moving into the on-demand library and the community gathering in Boston next week.

GPCRs are no longer simple on/off switches. Discover how biased signaling and functional assays are reshaping GPCR drug discovery.

Dr. GPCR and Eurofins DiscoverX announce a strategic partnership to accelerate GPCR drug discovery by expanding access to validated, industry-standard cell-based assay platforms supporting pharmacological characterization, screening, and regulatory-compliant development.