Conservation of Allosteric Ligand Binding Sites in G-Protein Coupled Receptors
GPCR News
- Nov 1, 2022
- 1 min
Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to inv
- Oct 1, 2022
- 1 min
Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex
- Oct 1, 2022
- 1 min
Mechanistic basis of GPCR activation explored by ensemble refinement of crystallographic structures
- Oct 1, 2022
- 1 min
Endogenous ligand recognition and structural transition of a human PTH receptor
- Oct 1, 2022
- 1 min
Comparative studies of AlphaFold, RoseTTAFold and Modeller: a case study involving the use of...
- Oct 1, 2022
- 1 min
Mechanism of enhanced sensitivity of mutated β-adrenergic-like octopamine receptor to amitraz in...
- Sep 1, 2022
- 1 min
PI(4,5)P 2-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-c
- Sep 1, 2022
- 1 min
Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand...
- Sep 1, 2022
- 1 min
Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane...
- Sep 1, 2022
- 1 min
C5aR2 receptor: The genomic twin of the flamboyant C5aR1
- Sep 1, 2022
- 1 min
The Gluopsins: Opsins without the Retinal Binding Lysine
- Sep 1, 2022
- 1 min
Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1
- Sep 1, 2022
- 1 min
To probe the activation mechanism of the Delta opioid receptor by an agonist ADL5859 started from...
- Sep 1, 2022
- 1 min
Structural basis for receptor selectivity and inverse agonism in S1P5 receptors
- Sep 1, 2022
- 1 min
Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify...
- Sep 1, 2022
- 1 min
A Setmelanotide-like Effect at MC4R Is Achieved by MC4R Dimer Separation
- Sep 1, 2022
- 1 min
Lipid Modulation of a Class B GPCR: Elucidating the Modulatory Role of PI(4,5)P 2 Lipids
- Sep 1, 2022
- 1 min
Computational study of the conformational ensemble of CX3C chemokine receptor 1 (CX3CR1) and its...
- Sep 1, 2022
- 1 min
Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR..