Location bias contributes to functionally selective responses of biased CXCR3 agonists
GPCR News
- Oct 1, 2022
- 1 min
Dual loss of regulator of G protein signaling 2 and 5 exacerbates ventricular myocyte arrhythmias...
- Oct 1, 2022
- 1 min
Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to...
- Oct 1, 2022
- 1 min
Recurrent hypoglycemia increases hepatic gluconeogenesis without affecting glycogen metabolism or sy
- Oct 1, 2022
- 1 min
Coincident Regulation of PLCβ Signaling by Gq-Coupled and μOpioid Receptors Opposes Opioid- Mediated
- Oct 1, 2022
- 1 min
Intermolecular Interactions in G Protein-Coupled Receptor Allosteric Sites at the Membrane Interface
- Oct 1, 2022
- 1 min
Glucagon receptor-mediated regulation of gluconeogenic gene transcription is endocytosis-dependent..
- Oct 1, 2022
- 2 min
Activation of GPR183 by 7 α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through...
- Oct 1, 2022
- 1 min
Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C...
- Oct 1, 2022
- 1 min
GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP
- Oct 1, 2022
- 1 min
Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
- Oct 1, 2022
- 1 min
N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 ...
- Oct 1, 2022
- 1 min
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
- Oct 1, 2022
- 1 min
A cryptic mode of GPCR regulation revealed
- Oct 1, 2022
- 2 min
Co-activation of GPCRs facilitate GIRK-dependent current
- Oct 1, 2022
- 1 min
Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and...
- Sep 1, 2022
- 1 min
Signaling pathways activated by sea bass gonadotropin-inhibitory hormone peptides in COS-7 cells...
- Sep 1, 2022
- 1 min
G protein coupling and activation of the metabotropic GABAB heterodimer
- Sep 1, 2022
- 1 min
GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization...
- Sep 1, 2022
- 1 min
C1-inhibitor influence on platelet activation by thrombin receptors agonists