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- New Tools, Smart Signals, and The Kenakin Brief
Explore this week’s research, tools, and biotech insights in one place. The insights are ready.
- GPCR Pharmacology Insights That Prevent Real Drug Discovery Failures
Kenakin revealed practical ways to anticipate these system-level interactions before they appear as Allosteric modulators interact with the system already in motion, shaping the receptor’s behavior without Enzyme Behavior: The Nonlinear Gatekeeper In GPCR programs, CYP interactions often appear late—usually It equips pharmacologists, discovery teams, and biotech leaders to see around mechanistic corners, recognize
- X4 slashes pipeline, lays off staff just three weeks after netting a $55M PIPE
The Boston biotech revealed Wednesday afternoon that it would downsize its research to focus on its lead
- Why Kinetics Matter More Than Kd in GPCR Drug Discovery
insights from major conferences, emerging research, and expert commentary Whether you’re a pharmacologist, biotech GPCR scientists, translational pharmacologists, biotech drug discovery teams, and decision-makers who
- 📰 GPCR Weekly News, October 9 to 15, 2023
Receptor Design and Synthesis of Novel GPR139 Agonists with Therapeutic Effects in Mouse Models of Social Interaction Immunoadsorption (RIA) in Post-COVID ME/CFS Patients with Elevated ß2-Adrenergic Receptor Autoantibodies-An Interim Chris Cargill Wins Executive of the Year at the Citeline Pharma Intelligence Awards Japan 2023 Salipro Biotech Conference November 20 - 23, 2023 | ASCEPT Annual Scientific Meeting February 3 - 7, 2024 | SLAS2024 International
- 📰 GPCR Weekly News, April 17 to 23, 2023
pathway of opioid drugs into cellular structures Inversago Pharma will present at BBHIC 2023 Orion Biotechnology attended the Swiss Biotech Day Addex Therapeutics attended the Swiss Biotech Day Sosei Heptares presented
- 📰 GPCR Weekly News, June 12 to 18, 2023
Pairaudeau, CTO of Exscientia discuss transforming drug discovery using their AI-driven platform Salipro Biotech I-GPCRNet (October 25 - 27, 2023) GPCR Retreat (November 2 - 4, 2023) Structure, Mechanism, and Drug Interactions
- Verily links up with Sosei Heptares for GPCR drug discovery
January 2022 "G-protein-coupled receptors’ star has been on the rise in biotech in recent years as researchers
- Septerna emerges with $100M to spark 'second golden age' of prolific drug target GPCR with ...
fruitful research space has led to more than 700 approved drugs over previous decades—but the two-year-old biotech
- Pharmacology at Your Fingertips: Terry’s Corner Launches
Plus: must-read chemokine and PTH1R papers, and new momentum across biotech—from Superluminal to Neurocrine
- Third Rock pushes newest fund over $1B line as it marks 15 years in venture capital
Since then, Celniker has helped usher in an additional fund and headed a few startups as interim CEO. That money has gone to some 60 biotechs, much of it as early funding."
- Inversago Pharma Announces Dosing of First Participant with Metabolic Syndrome in Phase 1B ...
(“Inversago”), a clinical stage biotech company with a unique portfolio of CB1 inverse agonists, announced
- 📰 GPCR Weekly News, September 4 to 10, 2023
Our partner, Domain Therapeutics, will attend the SACHS 23rd annual biotech event in Europe. Dr. Therapeutics CEO Pascal Neuville to Discuss Game-Changing GPCR-Targeting Immunotherapies at Sachs Associates' Biotech Conference November 20 - 23, 2023 | ASCEPT Annual Scientific Meeting February 3 - 7, 2024 | SLAS2024 International
- The Hidden Driver of GPCR Drug Success: Why Target Residence Time Matters More Than You Think
spots in your drug evaluation process, moving beyond simple potency measures to understand the dynamic interactions GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need
- 📰 GPCR Weekly News, February 6 to 12, 2023
Industry News Biotech startup Structure pulls off rare IPO, raising $161M 3-drug combo leads to 'unprecedented Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) arcoscreen is one of the 13 biotech SLAS2023 International Conference and Exhibition (February 25 - March 1, 2023). 2nd ERNEST Training School
- Accelerating GPCR Drug Discovery
I've seen this pattern unfold across biotech, academia, and nonprofits. The assays are running, data is flowing in from your CROs or your internal labs , yet progress stalls Internal data and CRO outputs misaligned with strategic goals.
- Assay Sensitivity: The Hidden Lever Driving GPCR Drug Discovery
For drug hunters working at the GPCR interface, the difference between a successful lead and a dead-end Kenakin Content trusted by biotech, pharma & academia 💎 $2999/year — one conference cost = a full If you’re still treating orthosteric and allosteric interactions as interchangeable, you’re leaving precision
- 📰 GPCR Weekly News, November 20 to 26, 2023
Updates in GPCR Research GproteinDb in 2024: new G protein-GPCR couplings, AlphaFold2-multimer models and interface interactions Experimental modulation of physiological force application on leg joint neurons in intact Showcases Innovative AI-Driven Drug Design at BRIC AI 2023 Workshop Salipro Biotech AB Celebrates Milestones Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk February 3 - 7, 2024 | SLAS2024 International
- Allosteric Binding Demystified: Smarter GPCR Drug Discovery
GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need
- 🎄 Have Yourself a Merry Little GPCRmas! ❄ Dec 9 - 15, 2024
unanswered questions about blockbuster weight-loss drugs Transforming Drug Discovery: Insights from Viva Biotech's Meeting 2025 May 12 - 15, 2025 | PEGS 2025 May 20 - 22, 2025 | SLAS Europe 2025 June 16 - 19, 2025 | BIO International
- 📰 GPCR Weekly News, December 11 to 17, 2023
epithelial proliferation, migration, and cellular respiration Spatiotemporal Optical Control of Gαq-PLCβ Interactions Biotherapeutics in Idiopathic Pulmonary Fibrosis Former execs from Pfizer obesity drug program have started a new biotech Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk February 3 - 7, 2024 | SLAS2024 International
- How Schild Analysis Protects Your Conclusions in GPCR Research
incretin biology depends on more than ligand potency — it hinges on where receptors actually are, how they internalize how his team uses fluorescence tools and chemically engineered ligands to map receptor distribution, internalization datasets, balancing innovation with assay rigor, or working across chemistry–pharmacology–physiology interfaces GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need
- 📰 GPCR Weekly News, March 25 to March 31, 2024
the Classified GPCR News from March 25th to March 31st, 2024 GPCR Activation and Signaling PACAP key interactions Secures VLAIO Grant Supporting Drug Discovery & Development In Endocrine And Metabolic Diseases How biotech Clinical Pharmacology 2026 GPCR Jobs Postdoctoral Associate Research Technologist I Senior Scientist- Internal
- Assay Volume Control: Your GPCR Drug Discovery Power Lever
curriculum with your topic suggestions Weekly new releases to stay ahead of the science Content built for biotech
- 📰 GPCR Weekly News
Surveying nonvisual arrestins reveals allosteric interactions between functional sites. of Alcohol and Substance Use Disorders AbbVie recruits a GPCR team in Oxford, buying out a fledgling biotech
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
To solve this industry-wide problem, Orion Biotechnology (Orion) is introducing a novel solution driven technological advances related to the understanding of structure and activation mechanisms of GPCRs, the biotech investment community has injected significant funding into small biotech companies developing novel About Orion Biotechnology Orion’s mission is to unlock the therapeutic potential of previously undruggable For more information, follow Orion Biotechnology on LinkedIn or visit www.orionbiotechnology.com.
- 📰 GPCR Weekly News, June 3 to June 9, 2024
26RFa by the pyroglutamylated RFamide peptide receptor Industry News NanoImaging Services and Cube Biotech
- Mechanism vs. Assumption: A Model-First Path to Getting GPCR MoA Right
GPCR scientists, translational pharmacologists, biotech discovery teams, platform company leaders, and
- GPCR News Flash! Top Updates You Can't-Miss! + University CheatSheet is finally available! ❄ Dec 2 - 8, 2024
Mid-2025 How GPCR agonists, including antibodies, are shaping the future of metabolic care Salipro Biotech Meeting 2025 May 12 - 15, 2025 | PEGS 2025 May 20 - 22, 2025 | SLAS Europe 2025 June 16 - 19, 2025 | BIO International assemble the ternary parathyroid hormone-GPCR-arrestin complex Myosin VI drives arrestin-independent internalization
- 📰 GPCR Weekly News, April 3 to 9, 2023
Industry News Orion Biotechnology at the AACR 2023. (April 20 - 21, 2023) Swiss Biotech Day (April 24 - 25, 2023) NEW ASPET 2023 - American Society for Pharmacology














