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Advanced data analysis for GPCR pharmacology

Dr. Samuel Hoare

Class 1 - Concentration-response analysis: Become a CRC super-user
Class 3 - Antagonist pharmacology and binding assay analysis
Class 2 - Quantifying agonist pharmacology and biased agonism
Class 4 - New dimensions of activity: Allosteric modulators and kinetics

Main objectives:


  • Learning how to perform advanced GPCR pharmacology data analysis in support of drug discovery and GPCR research, shown with GraphPad Prism.

  • Understanding the pharmacology data analysis framework we use for GPCRs.

  • Appreciating the practical realities, limitations, and tradeoffs of GPCR data analysis.

  • Learning many tips and tricks to improve your data analysis's quality, reliability, and efficiency.


The participants will increase their ability to perform, understand, and communicate GPCR pharmacology data analysis to a high level, as well as expertise that can be applied in drug discovery and target research to maximize the chances of project success.


The increased understanding will also be helpful for the participants in their training and education of entry-level scientists. Attendees will be provided with Prism files, Excel templates and simulators, and the PowerPoints of the workshop modules.



Modules:


  • Module 1 - Concentration-response analysis: Become a CRC super-user.

  • Module 2 - Quantifying agonist pharmacology and biased agonism.

  • Module 3 - Antagonist pharmacology and binding assay analysis.

  • Module 4 - New dimensions of activity: Allosteric modulators and kinetics.



Good to know:


  • Classes will be live from Zoom on Thursdays from 10 am to 12:00 pm EST.

  • Sessions will include a one-hour live lecture plus one hour of Q&A and discussion. Every participant will also have a 1:1 meeting with Dr. Hoare during or after the four weeks, scheduled according to the professor's availability.

  • Participants who complete the course will get an online certification signed by the professor and the Dr.GPCR Team.


What others are saying about the courses

Dr. Hoare is very experienced in the field. What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended. The really unexpected was that the Q&A sessions reached the highest level—beyond excellent.
I am a convert! I will keep Dr. GPCR and the offered resources in my work sphere

Anonymous

Dr. Hoare's extensive and elaborative explanation of the topics at hand was excellent and very digestible. Thoroughly enjoyed learning from him

Anonymous

Thank you for bringing this course with Dr. Kenakin. I wish Dr. GPCR the best for the sake of promoting more educational opportunities that are sorely needed in the field

Anonymous

Dr. Kenakin is a leading expert in the field. Aside from his vast experience in drug development, not to mention his extensive publication record, Dr. Kenakin is a masterful teacher and communicator.

Anonymous

The content had enough depth to satisfy the hunger for theory while being full of practical knowledge

Anonymous

The course was very practical and easily translatable to experiments that we could do in our own labs. It was clear that Dr. Hoare is very in touch with the technical and human challenges we encounter in our work

Anonymous

The best pharmacology teacher teaming up with the best GPCR community platform to help train and inspire the next generation of scientists. Also super-valuable for those of us learning how to teach pharmacology

Anonymous

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