GPCR Courses
Expert knowledge, flexible courses - career-ready skills —build skills that translate at the bench and in the boardroom.
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The Practical Assessment of Signaling Bias
Signaling bias is an inherent feature of pharmacology, influencing receptor behavior even when unnoticed.
Different ligands stabilize distinct receptor states, leading to diverse signaling outcomes.
Measuring and understanding bias helps design drugs that maximize therapeutic benefits while minimizing side effects.
Terry Kenakin
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Strategic Project Management for scientists
Gain practical project management skills explicitly designed for research and innovation.
Learn to plan, execute, and manage scientific projects while balancing timelines, resources, and team coordination.
Master strategic planning, risk assessment, and collaboration tools to boost efficiency and project success.
Yamina Berchiche
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Applying Pharmacology to Drug Discovery
Terry Kenakin
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Advanced data analysis for GPCR pharmacology
Class 1 - Concentration-response analysis: Become a CRC super-user
Class 2 - Quantifying agonist pharmacology and biased agonism
Class 3 - Antagonist pharmacology and binding assay analysis
Class 4 - New dimensions of activity: Allosteric modulators and kinetics
Sam Hoar
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Principles of Pharmacology in Drug Discovery II
Advanced Methods for the Optimization of Candidate Selection
Lecture 1: The Eyes to See- The Importance of Pharmacologic Assays
Lecture 2: Drug Disposition in Physiological Tissues as a Therapeutic Variable
Lecture 3: The Application of GPCR Ligand Kinetics to Candidate Design
Lecture 5: Unique Exploitable GPCR-Ligand Behaviors for Therapeutic Benefit
Terry Kenakin
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Principles of Pharmacology in Drug Discovery I
Techniques for Effective Lead Optimization of Candidate Molecules
Lecture 1: GPCR Project Initiation and Design for Discovery of New Molecules
Lecture 2: Drug Affinity: Measurement of Antagonism (Binding and Function) / Classifying Antagonists
Lecture 3: Agonists and Efficacy: A New World of GPCR Efficacies / Biased Signaling
Terry Kenakin
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