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- What are your thoughts on β2AR? Listen to Ep.163 of the @DrGPCR Podcast, where @DVeprintsev shares his thoughts and experiences about working with GPCRs, tips on framing your research correctly, and other insightful topics. Don’t miss out! ✳️https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr.-dmitry- #GPCRs #SciencePodcast #DrugDiscovery #Biotech #DrGPCR | Dr. GPCR Ecosystem
.163 of the @DrGPCR Podcast, where @DVeprintsev shares his thoughts and experiences about working with GPCRs ✳️https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr. GPCR Podcast What are your thoughts on β2AR? ✳️ https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr. -dmitry- #GPCRs #SciencePodcast #DrugDiscovery #Biotech #DrGPCR Previous Next Recent Articles
- Science isn't always about eureka moments—sometimes it's about steady progress. In our latest Dr. GPCR Podcast episode, Ian Chronis shares his top aha moments, from learning the hard way about gel electrophoresis to discovering the hidden complexities of GPCR signaling. ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology | Dr. GPCR Ecosystem
GPCR Podcast episode, Ian Chronis shares his top aha moments, from learning the hard way about gel electrophoresis to discovering the hidden complexities of GPCR signaling. ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast GPCR Podcast Science isn't always about eureka moments—sometimes it's about steady progress. GPCR Podcast episode, Ian Chronis shares his top aha moments, from learning the hard way about gel electrophoresis to discovering the hidden complexities of GPCR signaling. ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast
- A well-updated profile opens doors to collaborations and exciting GPCR projects 🚀 Don’t miss out—update yours now! | Dr. GPCR Ecosystem
Home → Flash News → A well-updated profile opens doors to collaborations and exciting GPCR projects 🚀 GPCR Profiles A well-updated profile opens doors to collaborations and exciting GPCR projects 🚀 Don’ www.ecosystem.drgpcr.com/account/my-account and meet all the fantastic scientists that are part of our community 😉 #gpcr
- Thank You Page | Dr. GPCR Ecosystem
GPCR Ecosystem! Stay tuned for updates, exclusive content, and exciting opportunities in the world of GPCR research.
- Leave for dinner reception | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Leaving for City Center | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- A newly engineered biosensor reveals DNAJC13 as a key player in GPCR trafficking, shedding light on its role in DOR downregulation and endosomal regulation. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/an-engineered-trafficking-biosensor-reveals-a-role-for-dnajc13-in-dor-downregulation #gpcr #drgpcr | Dr. GPCR Ecosystem
Home → Flash News → A newly engineered biosensor reveals DNAJC13 as a key player in GPCR trafficking, Check out the latest GPCR news in the Ecosystem today! #drgpcr Published on March 24, 2025 Category GPCR Weekly News A newly engineered biosensor reveals DNAJC13 as a key player in GPCR trafficking, shedding light on its role in DOR downregulation and endosomal Check out the latest GPCR news in the Ecosystem today!
- 🔍 Running a GPCR lab? Applying for grants? Launching a nonprofit? Ep.165 of the Dr.GPCR Podcast is your finance + operations crash course—delivered by two experts who support early-stage mission-driven teams like Dr. GPCR. 🎧 Smart, practical, and full of real talk: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup | Dr. GPCR Ecosystem
Home → Flash News → 🔍 Running a GPCR lab? Applying for grants? Launching a nonprofit? GPCR. 🎧 Smart, practical, and full of real talk: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup Published on May 15, 2025 Category Dr. GPCR Podcast 🔍 Running a GPCR lab? Applying for grants? Launching a nonprofit? Germain #gpcr #DrGPCR #ScienceStartup Previous Next Recent Articles
- 🚀 Ready to dive into the world of GPCR drug development? Join Dr. Terry Kenakin for the 4-week course “Development of GPCR Ligands as Therapeutic Drugs”! Get exclusive access to expert lectures, recordings, reading materials, and even a private call with Dr. Kenakin himself! Don’t miss this chance to level up your knowledge. 🔹 Spots are limited—save yours now! 👉 https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs #gpcr #drgpcr #pharmacolgy #drugdiscovery #research | Dr. GPCR Ecosystem
Home → Flash News → 🚀 Ready to dive into the world of GPCR drug development? Join Dr. Terry Kenakin for the 4-week course “Development of GPCR Ligands as Therapeutic Drugs”! GPCR Courses 🚀 Ready to dive into the world of GPCR drug development? Join Dr. Terry Kenakin for the 4-week course “Development of GPCR Ligands as Therapeutic Drugs”! #gpcr #drgpcr #pharmacolgy #drugdiscovery #research Previous Next Recent Articles
- GPCR Courses | Dr. GPCR Ecosystem
Discover top GPCR Courses for your educational journey. GPCR Community builder for scientists with expertise in GPCR project strategy and translational applications As a member, you can access: Dr.GPCR Podcast videos Live GPCR events Weekly classified GPCR news Contributor Private groups 30+ Symposia recorded talks GPCR Job listings GPCR Event listings Direct access to members the world's top GPCR experts.
- pharmacology at your fingertips terrys corner launches | Dr. GPCR Ecosystem
Flash News → pharmacology at your fingertips terrys corner launches Published on July 4, 2025 Category GPCR Weekly News Stronger pharmacology drives smarter decisions in GPCR discovery. GPCR Weekly: ♦️ Yamina’s Corner—GPCR consulting to de-risk and accelerate your pipeline ♦️ Celtarys’ validated TR-FRET assay for CB1/CB2 ♦️ Chemokine-GPCR selectivity decoded ♦️ PTH1R structures reveal https://www.ecosystem.drgpcr.com/post/pharmacology-at-your-fingertips-terry-s-corner-launches #DrGPCR #GPCR
- ep 175 with jens carlsson release picture | Dr. GPCR Ecosystem
Discover how embracing failure turned frustration into a breakthrough career designing GPCR experiments GPCR Podcast. Home → Flash News → ep 175 with jens carlsson release picture Model. Predict. GPCR Podcast What if a failed experiment became the best thing that ever happened to your career? Computational Biochemistry at Uppsala University , where his lab uses structure-based modeling to predict GPCR-ligand GPCR Podcast : https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/model-predict-discover #DrGPCR #GPCR
- Behind every great discovery is a great question 🚀 Dr. Dmitry Veprintsev shares how asking the right GPCR questions and dreaming big have shaped his work, in the latest Dr. GPCR podcast episode. If you’re passionate about GPCRs and drug discovery, this episode is a must-listen! ✳️Listen at Ep 163 with Dr. Dmitry Veprintsev #DrGPCR #GPCRPodcast #Biotech #Pharmacology #GPCRScience | Dr. GPCR Ecosystem
GPCR podcast episode. If you’re passionate about GPCRs and drug discovery, this episode is a must-listen! GPCR Podcast Behind every great discovery is a great question 🚀 Dr. GPCR podcast episode. If you’re passionate about GPCRs and drug discovery, this episode is a must-listen!
- In Ep.163 of the Dr. GPCR Podcast, Dr. Dmitry Veprintsev discusses the importance of asking the right GPCR question. It’s not just about learning the techniques; it’s about curiosity! 👀 Do you remember any question that changed your perspective completely? 💡 ✳️Visit https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr.-dmitry- #DrGPCR #GPCRPodcast #Pharmacology #DrugDiscovery #GPCRScience | Dr. GPCR Ecosystem
GPCR Podcast, Dr. Dmitry Veprintsev discusses the importance of asking the right GPCR question. 💡 ✳️Visit https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr. GPCR Podcast In Ep.163 of the Dr. GPCR Podcast, Dr. Dmitry Veprintsev discusses the importance of asking the right GPCR question. 💡 ✳️Visit https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr.
- Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox Unlocking the activation process of PTH1R: New computational insights into its molecular interactions bring us closer to better osteoporosis treatments! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/key-interaction-changes-determine-the-activation-process-of-human-parathyroid-hormone-type-1-receptor #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox Unlocking the activation process key-interaction-changes-determine-the-activation-process-of-human-parathyroid-hormone-type-1-receptor #gpcr #drgpcr Published on February 6, 2025 Category GPCR Weekly News Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox Unlocking the activation process key-interaction-changes-determine-the-activation-process-of-human-parathyroid-hormone-type-1-receptor #gpcr
- Did you know that GPR20, a potential therapeutic target to treat gastrointestinal stromal tumours, performs high constitutive activity when coupling with Gi? Check out this paper to see how molecular dynamics simulation can be used to explore its constitutive activation mechanism. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/exploring-the-constitutive-activation-mechanism-of-the-class-a-orphan-gpr20 #gpcr #drgpcr | Dr. GPCR Ecosystem
Check out the latest GPCR news in the Ecosystem today! #drgpcr Published on February 13, 2025 Category GPCR Weekly News Did you know that GPR20, a potential Check out the latest GPCR news in the Ecosystem today! Operating cadence Attila Foris Dec 24, 2025 GPCR Binding Affinity Experiments: Interpreting Data With Yet discovery teams routinely lose time and misallocate resources because the underlying biology behaves
- What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment? That’s precisely what Dr. Kotliar from the Sakmar lab made possible! In Ep.167 of the Dr. GPCR Podcast, we chat with Drs. Tom Sakmar and Ilana Kotliar about how their lab developed: A multiplexed Luminex assay to screen hundreds of interactions at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations This is open-access science at its best, built for the GPCR research community. ✳️ Listen to the episode: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRresearch #DrGPCRecosystem #GPCRdrugdiscovery #GPCRtrainingprogram #GPCRpodcast | Dr. GPCR Ecosystem
Home → Flash News → What if you could map GPCR-RAMP interactions across the entire superfamily in a single GPCR Podcast, we chat with Drs. library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations GPCR Podcast What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment GPCR Podcast, we chat with Drs.
- A new study from the Hudson Lab at the University of Glasgow shows that the FFA receptor antagonist AH7614 is actually an inverse agonist - suppressing fat cell formation, boosting lipolysis and reducing glucose uptake. Explore how targeting FFA4 could help fight metabolic disorders. Catch up with the latest research conducted in the Hudson lab in Ep. 161 of the Dr. GPCR Podcast. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/inverse-agonism-of-the-ffa4-free-fatty-acid-receptor-controls-both-adipogenesis-and-mature-adipocyte-function #GPCR #drGPCR #FFA4 #metabolism #adipocytes” | Dr. GPCR Ecosystem
GPCR Podcast. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com #GPCR #drGPCR #FFA4 #metabolism #adipocytes” Published on April 7, 2025 Category GPCR Weekly News A GPCR Podcast. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https:// www.ecosystem.drgpcr.com
- Class B GPCR drugs are reshaping treatment for migraine, diabetes, and obesity- but did you know ligand bias plays a key role in their success? This new review explores how tweaking peptide drugs can boost efficacy, reduce side effects, and unlock next-gen therapies. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/reviews/where-are-we-now%3F-biased-signalling-of-class-b-g-protein-coupled-receptor-targeted-therapeutics #gpcr#drgpcr | Dr. GPCR Ecosystem
Home → Flash News → Class B GPCR drugs are reshaping treatment for migraine, diabetes, and obesity- but GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com /where-are-we-now%3F-biased-signalling-of-class-b-g-protein-coupled-receptor-targeted-therapeutics #gpcr #drgpcr Published on June 2, 2025 Category GPCR Weekly News Class B GPCR drugs are reshaping treatment GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com
- This new study reveals how the conformation of parathyroid hormone (PTH) and the C-terminal helix α5 of Gα regulate the selective coupling of PTH1R to Gs or Gq. Through Cryo-EM and single-cell experiments, the authors show differences in binding affinity, duration, and strength. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/allosteric-mechanism-in-the-distinctive-coupling-of-gq-and-gs-to-the-parathyroid-hormone-type-1-receptor #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com /structural-and-molecular-insights-into-gpcr-function/allosteric-mechanism-in-the-distinctive-coupling-of-gq-and-gs-to-the-parathyroid-hormone-type -1-receptor #gpcr #drgpcr Published on April 28, 2025 Category GPCR Weekly News This new study reveals GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com -1-receptor #gpcr #drgpcr Previous Next Recent Articles
- How does a superagonist activate M2 muscarinic receptors? New simulations reveal the conformational changes from inactive to active states to highlighting how ligand dynamics drive GPCR activation! Catch the full story in the Ecosystem! https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/visualizing-agonist-induced-m2-receptor-activation-regulated-by-aromatic-ring-dynamics #GPCR #drGPCR #M2R #drugdiscovery #moleculardynamics | Dr. GPCR Ecosystem
the conformational changes from inactive to active states to highlighting how ligand dynamics drive GPCR -receptor-activation-regulated-by-aromatic-ring-dynamics #GPCR #drGPCR #M2R #drugdiscovery #moleculardynamics Published on March 31, 2025 Category GPCR Weekly News How does a superagonist activate M2 muscarinic the conformational changes from inactive to active states to highlighting how ligand dynamics drive GPCR -receptor-activation-regulated-by-aromatic-ring-dynamics #GPCR #drGPCR #M2R #drugdiscovery #moleculardynamics
- Do you remember the first time you were left alone in the lab with an experiment? 🤔 Did your experience compare to Dr. Brian Hudson’s? 😄 Tune into this week’s Dr. GPCR Podcast for great stories, GPCR insights, and a fascinating journey that led Dr. Hudson to years of groundbreaking research at the University of Glasgow. Don’t miss out! ✅Listen now https://buff.ly/aEQGUFl #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Podcast for great stories, GPCR insights, and a fascinating journey that led Dr. ✅Listen now https://buff.ly/aEQGUFl #gpcr #drgpcr Published on March 17, 2025 Category Dr. GPCR Podcast Do you remember the first time you were left alone in the lab with an experiment? GPCR Podcast for great stories, GPCR insights, and a fascinating journey that led Dr. ✅Listen now https://buff.ly/aEQGUFl #gpcr #drgpcr Previous Next Recent Articles
- Applying Pharmacology to Drug Discovery | Dr. GPCR Ecosystem
Terry Kenakin Get Started Premium Members benefits: - Subscribe and save 25% on every GPCR Course - Early-bird access - Recordings will be available < Back to GPCR courses Watch recording Your Instructor Dr.
- The Practical Assessment of Signaling Bias | Dr. GPCR Ecosystem
Terry Kenakin Get Started Premium Members benefits: - Subscribe and save 25% on every GPCR Course - Early-bird access - Recordings will be available < Back to GPCR courses Watch recording Your Instructor Dr.
- Strategic Project Management for scientists | Dr. GPCR Ecosystem
Yamina Berchiche Get Started Premium Members benefits: - Subscribe and save 25% on every GPCR Course - Early-bird access - Recordings will be available < Back to GPCR courses Watch recording Your Instructor
- Complimentary Reception dinner | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Forget one receptor at a time. Go big.Ep.167 of the Dr.GPCR Podcast with Tom Sakmar & Ilana Kotliar is about scaling GPCR research with multiplexing, miniaturization, and collaboration. The tools are built. The data is free. What will you ask next? 📲 Dive in: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRtraining #GPCRresearchcommunity #DrGPCR #GPCRdata | Dr. GPCR Ecosystem
Go big.Ep.167 of the Dr.GPCR Podcast with Tom Sakmar & Ilana Kotliar is about scaling GPCR research with GPCR Podcast Forget one receptor at a time. Go big.Ep.167 of the Dr.GPCR Podcast with Tom Sakmar & Ilana Kotliar is about scaling GPCR research with Operating cadence Attila Foris Dec 24, 2025 GPCR Binding Affinity Experiments: Interpreting Data With Yet discovery teams routinely lose time and misallocate resources because the underlying biology behaves
- Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep.166 of the Dr.GPCR Podcast,. The catch? It’s all about understanding the system, not replacing it. From neuromas to novel modulators, this episode is full of breakthroughs that matter for patients. 📲 Watch now: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Home → Flash News → Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep GPCR Podcast Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep.166 of Operating cadence Attila Foris Dec 24, 2025 GPCR Binding Affinity Experiments: Interpreting Data With GPCR News Dec 18, 2025 Scientific Isolation: The Real Reason Early Biotechs Lose Traction The Quiet Drift Yet discovery teams routinely lose time and misallocate resources because the underlying biology behaves
- How do GRK-specific phosphorylation barcodes influence β-arrestin binding to GPCRs? New cryo-EM structures from Chen et al. (Nature, 2025) reveal that β-arrestin1 and β-arrestin2 form distinct complexes with ACKR3 depending on whether it's phosphorylated by GRK2 or GRK5, shaping arrestin conformation, complex stability, and engagement mode. Surprisingly, arrestin’s finger loop didn’t dive into the receptor core. Instead, it latched onto the micelle surface, breaking canonical expectations. Also, β-arrestin2 lacks a membrane anchor, making it more dynamic — a potential clue to its functional specialization. These findings underscore how barcode location + arrestin isoform = unique signaling outcomes. open book Read the full study: Inside Out: Mapping GPCRs from Membrane Codes to Market Moves #GPCRs #Arrestin #ACKR3 #GRKs #CryoEM #StructuralBiology #SignalingBias #Phosphorylation #DrGPCR | Dr. GPCR Ecosystem
Home → Flash News → How do GRK-specific phosphorylation barcodes influence β-arrestin binding to GPCRs + arrestin isoform = unique signaling outcomes. open book Read the full study: Inside Out: Mapping GPCRs barcodes influence β-arrestin binding to GPCRs? Read the full study: Inside Out: Mapping GPCRs from Membrane Codes to Market Moves #GPCRs #Arrestin # Yet discovery teams routinely lose time and misallocate resources because the underlying biology behaves
- ep 175 with jens carlsson clip 2 | Dr. GPCR Ecosystem
Discover how strategic collaboration drives real GPCR drug discovery impact. GPCR Podcast If your model can’t change an experiment, what’s the point? That’s the standard Dr. In GPCR drug discovery, where complexity is the rule and timelines are tight, this kind of cross-functional GPCR Podcast: model predict discover #DrGPCR #GPCR #CollaborationInScience #ComputationalChemistry #Pharmacology
