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- Dr. Robert J. Lefkowitz | Dr. GPCR Ecosystem
GPCR Podcast Strategic Partners Dr. Robert J. His legacy lies in the numerous discoveries he and his team made in the GPCR field and in all those who GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research How GPCR Spatial Signaling Sparked a Scientific Journey Thanks for listening to this podcast episode
- A well-updated profile opens doors to collaborations and exciting GPCR projects 🚀 Don’t miss out—update yours now! | Dr. GPCR Ecosystem
Home → Flash News → A well-updated profile opens doors to collaborations and exciting GPCR projects 🚀 GPCR Profiles A well-updated profile opens doors to collaborations and exciting GPCR projects 🚀 Don’ www.ecosystem.drgpcr.com/account/my-account and meet all the fantastic scientists that are part of our community 😉 #gpcr
- Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma Date & She is currently working to understand the signaling and degradation of GPCRs in disease states to help GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- Thank You Page | Dr. GPCR Ecosystem
GPCR Ecosystem! Stay tuned for updates, exclusive content, and exciting opportunities in the world of GPCR research.
- Dr. GPCR University is officially back! 🎆 Join Dr. Terry Kenakin for "The Practical Assessment of Signaling Bias" workshop! 🚀 Learn the practical issues with detecting, measuring, and quantifying GPCR ligand-biased signaling. ✳️Early Bird discounts for Premium Members! ➡️Register today at https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR University is officially back! 🎆 Join Dr. 🚀 Learn the practical issues with detecting, measuring, and quantifying GPCR ligand-biased signaling #drgpcr Published on January 20, 2025 Category GPCR University Dr. GPCR University is officially back! 🎆 Join Dr. 🚀 Learn the practical issues with detecting, measuring, and quantifying GPCR ligand-biased signaling
- 🔍 Running a GPCR lab? Applying for grants? Launching a nonprofit? Ep.165 of the Dr.GPCR Podcast is your finance + operations crash course—delivered by two experts who support early-stage mission-driven teams like Dr. GPCR. 🎧 Smart, practical, and full of real talk: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup | Dr. GPCR Ecosystem
Home → Flash News → 🔍 Running a GPCR lab? Applying for grants? Launching a nonprofit? GPCR. 🎧 Smart, practical, and full of real talk: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup Published on May 15, 2025 Category Dr. GPCR Podcast 🔍 Running a GPCR lab? Applying for grants? Launching a nonprofit? Germain #gpcr #DrGPCR #ScienceStartup Previous Next Recent Articles
- A newly engineered biosensor reveals DNAJC13 as a key player in GPCR trafficking, shedding light on its role in DOR downregulation and endosomal regulation. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/an-engineered-trafficking-biosensor-reveals-a-role-for-dnajc13-in-dor-downregulation #gpcr #drgpcr | Dr. GPCR Ecosystem
Home → Flash News → A newly engineered biosensor reveals DNAJC13 as a key player in GPCR trafficking, Check out the latest GPCR news in the Ecosystem today! #drgpcr Published on March 24, 2025 Category GPCR Weekly News A newly engineered biosensor reveals DNAJC13 as a key player in GPCR trafficking, shedding light on its role in DOR downregulation and endosomal Check out the latest GPCR news in the Ecosystem today!
- ep 175 with jens carlsson release picture | Dr. GPCR Ecosystem
Discover how embracing failure turned frustration into a breakthrough career designing GPCR experiments GPCR Podcast. Home → Flash News → ep 175 with jens carlsson release picture Model. Predict. GPCR Podcast What if a failed experiment became the best thing that ever happened to your career? Computational Biochemistry at Uppsala University , where his lab uses structure-based modeling to predict GPCR-ligand GPCR Podcast : https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/model-predict-discover #DrGPCR #GPCR
- Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox Unlocking the activation process of PTH1R: New computational insights into its molecular interactions bring us closer to better osteoporosis treatments! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/key-interaction-changes-determine-the-activation-process-of-human-parathyroid-hormone-type-1-receptor #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox Unlocking the activation process key-interaction-changes-determine-the-activation-process-of-human-parathyroid-hormone-type-1-receptor #gpcr #drgpcr Published on February 6, 2025 Category GPCR Weekly News Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox Unlocking the activation process key-interaction-changes-determine-the-activation-process-of-human-parathyroid-hormone-type-1-receptor #gpcr
- In case you haven’t heard, registrations are open for the next 4-week course “Development of GPCR Ligands as Therapeutic Drugs,” with Dr. Terry Kenakin 👏 Spots are filling up fast, run and save yours, and enjoy a 25% discount with your Premium Membership 🚀 ✳️Go to https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs #gpcr #drgpcr | Dr. GPCR Ecosystem
News → In case you haven’t heard, registrations are open for the next 4-week course “Development of GPCR #gpcr #drgpcr Published on February 22, 2025 Category Dr. GPCR Courses In case you haven’t heard, registrations are open for the next 4-week course “Development of GPCR Ligands as Therapeutic Drugs,” with Dr. #gpcr #drgpcr Previous Next Recent Articles
- Complimentary Reception dinner | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment? That’s precisely what Dr. Kotliar from the Sakmar lab made possible! In Ep.167 of the Dr. GPCR Podcast, we chat with Drs. Tom Sakmar and Ilana Kotliar about how their lab developed: A multiplexed Luminex assay to screen hundreds of interactions at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations This is open-access science at its best, built for the GPCR research community. ✳️ Listen to the episode: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRresearch #DrGPCRecosystem #GPCRdrugdiscovery #GPCRtrainingprogram #GPCRpodcast | Dr. GPCR Ecosystem
Home → Flash News → What if you could map GPCR-RAMP interactions across the entire superfamily in a single GPCR Podcast, we chat with Drs. library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations GPCR Podcast What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment GPCR Podcast, we chat with Drs.
- A new study from the Hudson Lab at the University of Glasgow shows that the FFA receptor antagonist AH7614 is actually an inverse agonist - suppressing fat cell formation, boosting lipolysis and reducing glucose uptake. Explore how targeting FFA4 could help fight metabolic disorders. Catch up with the latest research conducted in the Hudson lab in Ep. 161 of the Dr. GPCR Podcast. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/inverse-agonism-of-the-ffa4-free-fatty-acid-receptor-controls-both-adipogenesis-and-mature-adipocyte-function #GPCR #drGPCR #FFA4 #metabolism #adipocytes” | Dr. GPCR Ecosystem
GPCR Podcast. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com #GPCR #drGPCR #FFA4 #metabolism #adipocytes” Published on April 7, 2025 Category GPCR Weekly News A GPCR Podcast. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https:// www.ecosystem.drgpcr.com
- This new study reveals how the conformation of parathyroid hormone (PTH) and the C-terminal helix α5 of Gα regulate the selective coupling of PTH1R to Gs or Gq. Through Cryo-EM and single-cell experiments, the authors show differences in binding affinity, duration, and strength. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/allosteric-mechanism-in-the-distinctive-coupling-of-gq-and-gs-to-the-parathyroid-hormone-type-1-receptor #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com /structural-and-molecular-insights-into-gpcr-function/allosteric-mechanism-in-the-distinctive-coupling-of-gq-and-gs-to-the-parathyroid-hormone-type -1-receptor #gpcr #drgpcr Published on April 28, 2025 Category GPCR Weekly News This new study reveals GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com -1-receptor #gpcr #drgpcr Previous Next Recent Articles
- Class B GPCR drugs are reshaping treatment for migraine, diabetes, and obesity- but did you know ligand bias plays a key role in their success? This new review explores how tweaking peptide drugs can boost efficacy, reduce side effects, and unlock next-gen therapies. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/reviews/where-are-we-now%3F-biased-signalling-of-class-b-g-protein-coupled-receptor-targeted-therapeutics #gpcr#drgpcr | Dr. GPCR Ecosystem
Home → Flash News → Class B GPCR drugs are reshaping treatment for migraine, diabetes, and obesity- but GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com /where-are-we-now%3F-biased-signalling-of-class-b-g-protein-coupled-receptor-targeted-therapeutics #gpcr #drgpcr Published on June 2, 2025 Category GPCR Weekly News Class B GPCR drugs are reshaping treatment GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com
- How does a superagonist activate M2 muscarinic receptors? New simulations reveal the conformational changes from inactive to active states to highlighting how ligand dynamics drive GPCR activation! Catch the full story in the Ecosystem! https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/visualizing-agonist-induced-m2-receptor-activation-regulated-by-aromatic-ring-dynamics #GPCR #drGPCR #M2R #drugdiscovery #moleculardynamics | Dr. GPCR Ecosystem
the conformational changes from inactive to active states to highlighting how ligand dynamics drive GPCR -receptor-activation-regulated-by-aromatic-ring-dynamics #GPCR #drGPCR #M2R #drugdiscovery #moleculardynamics Published on March 31, 2025 Category GPCR Weekly News How does a superagonist activate M2 muscarinic the conformational changes from inactive to active states to highlighting how ligand dynamics drive GPCR -receptor-activation-regulated-by-aromatic-ring-dynamics #GPCR #drGPCR #M2R #drugdiscovery #moleculardynamics
- An opportunity you won’t want to miss! ⚠️ The next 4-week course with Dr. Terry Kenakin, “Development of GPCR Ligands as Therapeutic Drugs” is coming up 🧐 Be the first to register, save your spot, and spread the word. This event will only happen once this year! ✳️Go to https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs for more information! #gpcr #drgpcr | Dr. GPCR Ecosystem
Terry Kenakin, “Development of GPCR Ligands as Therapeutic Drugs” is coming up 🧐 Be the first to register #gpcr #drgpcr Published on February 19, 2025 Category Dr. GPCR Courses An opportunity you won’t want to miss! ⚠️ The next 4-week course with Dr. Terry Kenakin, “Development of GPCR Ligands as Therapeutic Drugs” is coming up 🧐 Be the first to register #gpcr #drgpcr Previous Next Recent Articles
- Do you remember the first time you were left alone in the lab with an experiment? 🤔 Did your experience compare to Dr. Brian Hudson’s? 😄 Tune into this week’s Dr. GPCR Podcast for great stories, GPCR insights, and a fascinating journey that led Dr. Hudson to years of groundbreaking research at the University of Glasgow. Don’t miss out! ✅Listen now https://buff.ly/aEQGUFl #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Podcast for great stories, GPCR insights, and a fascinating journey that led Dr. ✅Listen now https://buff.ly/aEQGUFl #gpcr #drgpcr Published on March 17, 2025 Category Dr. GPCR Podcast Do you remember the first time you were left alone in the lab with an experiment? GPCR Podcast for great stories, GPCR insights, and a fascinating journey that led Dr. ✅Listen now https://buff.ly/aEQGUFl #gpcr #drgpcr Previous Next Recent Articles
- Strategic Project Management for scientists | Dr. GPCR Ecosystem
Yamina Berchiche Get Started Premium Members benefits: - Subscribe and save 25% on every GPCR Course - Early-bird access - Recordings will be available < Back to GPCR courses Watch recording Your Instructor
- The Practical Assessment of Signaling Bias | Dr. GPCR Ecosystem
Terry Kenakin Get Started Premium Members benefits: - Subscribe and save 25% on every GPCR Course - Early-bird access - Recordings will be available < Back to GPCR courses Watch recording Your Instructor Dr.
- Dr. Thomas P. Sakmar | Dr. GPCR Ecosystem
GPCR Podcast Strategic Partners Dr. Thomas P. Sakmar About Dr. Thomas P. made early key contributions and developed strategies to express, reconstitute and assay engineered GPCRs GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research How GPCR Spatial Signaling Sparked a Scientific Journey Thanks for listening to this podcast episode
- Unlock the full potential of the Dr. GPCR platform by updating your profile 🧬 Find like-minded scientists, and colleagues who work on the same topic as you 🙌 ✳️Go to https://www.ecosystem.drgpcr.com/account/my-account and update your profile #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR platform by updating your profile 🧬 Find like-minded scientists, and colleagues who work on the topic as you 🙌 ✳️Go to https://www.ecosystem.drgpcr.com/account/my-account and update your profile #gpcr GPCR Profiles Unlock the full potential of the Dr. GPCR platform by updating your profile 🧬 Find like-minded scientists, and colleagues who work on the topic as you 🙌 ✳️Go to https://www.ecosystem.drgpcr.com/account/my-account and update your profile #gpcr
- Registration & Coffee with light breakfast | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Coffee Break with lights snacks | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Can we preserve opioid pain relief without the side effects? 🔬 On Ep.166 of the Dr.GPCR Podcast, Ben Clements shares how positive allosteric modulators (PAMs) at the mu-opioid receptor could revolutionize treatment —with a 10x boost in methadone efficacy. Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship. 🎧 Full episode: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship GPCR Podcast Can we preserve opioid pain relief without the side effects? Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship
- Dr. Alix A. J. Rouault | Dr. GPCR Ecosystem
GPCR Podcast Strategic Partners Dr. Alix A. J. Rouault About Dr. Alix A. J. Cone was the first to clone the melanocortin receptors (the GPCRs that led to the discovery of MRAP2) GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration Built an Innovation Engine From Pipettes to Platforms: The Evolution of GPCR Research How GPCR Spatial Signaling Sparked a Scientific Journey Thanks for listening to this podcast episode
- What do GPCRs, acidic endosomes, and cancer immunotherapy have in common? Find out in our latest episode featuring Ian Chronis, where we explore the surprising ways GPR65 signals in different environments! ✅ Tune in: https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast | Dr. GPCR Ecosystem
Home → Flash News → What do GPCRs, acidic endosomes, and cancer immunotherapy have in common? ✅ Tune in: https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast Published on April 15, 2025 Category GPCR Podcast What do GPCRs, acidic endosomes, and cancer immunotherapy have in common? ✅ Tune in: https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast Previous Next Recent Articles
- Board meeting/General assembly | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- A high-resolution deep mutational scan of MC4R reveals how thousands of genetic variants impact obesity-linked signaling pathways and highlights new opportunities for precision drug discovery Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr#drgpcr | Dr. GPCR Ecosystem
GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr #drgpcr Published on May 5, 2025 Category GPCR Weekly News A high-resolution deep mutational scan of GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr
- Disrupting VIPR2 dimerisation halts breast cancer spread—could TM3-4 peptides be the next breakthrough in targeted cancer therapy? Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️ https://www.ecosystem.drgpcr.com/gpcrs-in-oncology-and-immunology/dimerisation-of-the-vip-receptor-vipr2-is-essential-to-its-binding-vip-and-g%CE%B1i-proteins%2C-and-to-its-functions-in-breast-cancer-cells #gpcr#drgpcr | Dr. GPCR Ecosystem
Check out the latest GPCR news in the Ecosystem today! ➡️ https://www.ecosystem.drgpcr.com/gpcrs-in-oncology-and-immunology/dimerisation-of-the-vip-receptor-vipr2 is-essential-to-its-binding-vip-and-g%CE%B1i-proteins%2C-and-to-its-functions-in-breast-cancer-cells #gpcr #drgpcr Published on May 12, 2025 Category GPCR Weekly News Disrupting VIPR2 dimerisation halts breast Check out the latest GPCR news in the Ecosystem today!
