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- What can an updated profile do for you? 🔎 Personalized content, better networking, and collaboration opportunities. Fill in the blanks—update now! ✳️Visit https://bit.ly/4fY4UHV today #gpcr #drgpcr | Dr. GPCR Ecosystem
✳️Visit https://bit.ly/4fY4UHV today #gpcr #drgpcr Published on January 15, 2025 Category Dr. GPCR Profiles What can an updated profile do for you? ✳️Visit https://bit.ly/4fY4UHV today #gpcr #drgpcr Recent Articles Previous Next
- A complete profile = a complete YOU. Highlight your publications, skills, and interests to connect with the right people! ✳️Go to https://www.ecosystem.drgpcr.com/account/my-account and update your profile on the Dr.GPCR. #gpcr #drgpcr | Dr. GPCR Ecosystem
#gpcr #drgpcr Published on February 5, 2025 Category Dr. GPCR Profiles A complete profile = a complete YOU. #gpcr #drgpcr Recent Articles Previous Next
- New insights into FPR2 signaling! GRK5 drives FPR2 endocytosis, but β-arrestin plays a pivotal role in postendocytic trafficking, plasma membrane recycling, and regulating signal transduction. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/grk5-regulates-endocytosis-of-fpr2-independent-of-%CE%B2-arrestins #gpcr #drgpcr | Dr. GPCR Ecosystem
Check out the latest GPCR news in the Ecosystem today! receptor-activation-and-signaling/grk5-regulates-endocytosis-of-fpr2-independent-of-%CE%B2-arrestins #gpcr #drgpcr Published on January 30, 2025 Category GPCR Weekly News New insights into FPR2 signaling! Check out the latest GPCR news in the Ecosystem today! receptor-activation-and-signaling/grk5-regulates-endocytosis-of-fpr2-independent-of-%CE%B2-arrestins #gpcr
- Did you know registrations are already open for all our 2025 Dr.GPCR University Courses? Check out what you can learn this year from the master, Dr. Terry Kenakin 😉and save your spot soon! Remember Premium Members get a 25% discount 🙌 ✳️Click here and start your next learning experience https://www.ecosystem.drgpcr.com/gpcr-courses #gpcr #drgpcr | Dr. GPCR Ecosystem
25% discount 🙌 ✳️Click here and start your next learning experience https://www.ecosystem.drgpcr.com/gpcr-courses #gpcr #drgpcr Published on February 18, 2025 Category GPCR Weekly News Did you know registrations are discount 🙌 ✳️ Click here and start your next learning experience https://www.ecosystem.drgpcr.com/gpcr-courses #gpcr #drgpcr Recent Articles Previous Next
- Check out the new optical BRET-based biosensor, Gαi bONE-GO! In neuronal cell lines, the use of Gαi bONE-GO revealed that several natural opioid neuropeptides act as partial agonists, contrary to their previous characterization as full agonists. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://buff.ly/e6gAlBv #gpcr#drgpcr | Dr. GPCR Ecosystem
Check out the latest GPCR news in the Ecosystem today! ➡️https://buff.ly/e6gAlBv #gpcr#drgpcr Published on April 21, 2025 Category GPCR Weekly News Check out Check out the latest GPCR news in the Ecosystem today! ➡️ https:// buff.ly/e6gAlBv #gpcr#drgpcr Recent Articles Previous Next
- Ep 145 with Dr John Janetzko
GPCR Podcast << Back to podcast list Dr. John Janetzko About Dr. Besides research, I am passionate about teaching, science communication and making research more inclusive GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy. The conversation concluded with both John and Yamina expressing a desire to support the academic community GPCR Podcast? Leave a Review.
- Ep 60 with Dr. Josephine (Pina) Cardarelli
GPCR Podcast << Back to podcast list Dr. Josephine (Pina) Cardarelli About Dr. of GPCR Therapeutics, USA, a newly incorporated Biotechnology company in the Bay Area. Additionally, they have a library of target GPCR heteromers for Oncology. Dr. Cardarelli heads the team of talented researchers that will be expanding at the US site. Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.
- ep 169 with sokhom pin some 2 | Dr. GPCR Ecosystem
GPCR Podcast Build the team you always wished you had. At Alkermes, Sokhom S. It was leadership. ✳️ Watch Ep. 169: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-169-with-dr-sokhom-pin
- Weekly News October 16 | Dr. GPCR Ecosystem
Home → Flash News → Weekly News October 16 Published on October 16, 2025 Category GPCR Weekly News Enzymes #DrGPCR #GPCR Recent Articles Previous Next
- Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep.166 of the Dr.GPCR Podcast,. The catch? It’s all about understanding the system, not replacing it. From neuromas to novel modulators, this episode is full of breakthroughs that matter for patients. 📲 Watch now: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Home → Flash News → Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep GPCR Podcast Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep.166 of . 3 hours ago Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox Dr. Jens Carlsson reveals how predictive modeling is reshaping GPCR drug discovery—bridging computation, Models Can GPCR models predict biology?
- Partners Submition Form | Dr. GPCR Ecosystem
GPCR Ecosystem and collaborate with us to make a positive impact.
- Ep 50 with Dr. Thomas P. Sakmar
GPCR Podcast << Back to podcast list Dr. Thomas P. Sakmar About Dr. Thomas P. where he was exposed for the first time to the nascent field of membrane biophysics and intercellular communication made early key contributions and developed strategies to express, reconstitute and assay engineered GPCRs GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling
- Content Guidelines | Dr. GPCR Ecosystem
GPCR Ecosystem website. Get the information you need to create engaging and impactful content. GPCR, Corp, LLC (“Dr. GPCR”) provides its Service to you through our websites referred to as Dr. GPCR, Ecosystem.DrGPCR.com, DrGPCR.com. Please note that Ecosystem.DrGPCR.com is specializes in GPCR and related subjects. GPCR conducts business Affiliate Policy Content and Conduct Policy Content Guidance Privacy Policy Terms
- irreversible drugs post 1 | Dr. GPCR Ecosystem
GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #DrugDiscovery #MedicinalChemistry #PKPD #ReceptorKinetics
- In case you haven’t heard, Dr. Terry Kenakin will soon start the course Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection 📖 The five-lecture series describes essential additional elements to GPCR discovery programs that extend the discovery process and increase therapeutic opportunity. | Dr. GPCR Ecosystem
Optimization of Candidate Selection 📖 The five-lecture series describes essential additional elements to GPCR GPCR Courses In case you haven’t heard, Dr. Optimization of Candidate Selection 📖 The five-lecture series describes essential additional elements to GPCR https://www.ecosystem.drgpcr.com/advanced-methods-for-the-optimization-of-candidate-selection #gpcr #
- 🚨 Exciting Opportunity for Professionals in Drug Development! 🚨 Register today for a one-of-a-kind online course at Dr. GPCR University: "Development of GPCR Ligands as Therapeutic Drugs." 🗓 Dates: March 20 - April 10, 2025 ⏰ Time: Thursdays, 10:00 AM - 11:30 AM (EST) This advanced course is essential for anyone working in drug development and focuses on: The essentials of new drug development Key pharmacokinetic elements (absorption, distribution, clearance) Hepatic metabolism and the Cytochrome P450 system Drug safety and toxicology (including drug-drug interactions) And much more! Gain deep insights into GPCR drug candidates and learn the critical assays and techniques required to bring therapeutic molecules to life. 🚨 Only 25 spots available — register now! 💡 This is a great opportunity for both academia and industry professionals. Sessions will be live, and you’ll also have 1:1 discussion time with the instructor. Full PDFs of the slides will be available! 🔗 https://buff.ly/lVEcRUc #GPCR #DrugDevelopment #Pharmacokinetics #TherapeuticDrugs #OnlineCourse #DrGPCRUniversity #PharmaceuticalIndustry | Dr. GPCR Ecosystem
GPCR University: "Development of GPCR Ligands as Therapeutic Drugs." 🗓 Dates: March 20 - April 10, 2025 Gain deep insights into GPCR drug candidates and learn the critical assays and techniques required to 🔗 https://buff.ly/lVEcRUc #GPCR #DrugDevelopment #Pharmacokinetics #TherapeuticDrugs #OnlineCourse # GPCR Courses 🚨 Exciting Opportunity for Professionals in Drug Development! GPCR University: "Development of GPCR Ligands as Therapeutic Drugs." 🗓 Dates: March 20 - April 10, 2025
- irreversible drugs post 3 | Dr. GPCR Ecosystem
GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #DrugDiscovery #Kinetics #ReceptorPharmacology #MedicinalChemistry
- 🎧 "You will always feel like you know nothing— and that’s completely fine." In Ep.162 of the Dr.GPCR Podcast, Dr. Gabriele Kockelkoren shares: 🔬 How GPCR spatial organization shapes signaling and drug responses 🌍 His interdisciplinary journey from physics to pharmacology 💡 Why embracing the unknown is key to scientific breakthroughs A must-listen for biophysicists, pharmacologists, and drug hunters pushing the boundaries of discovery! 🎙️ Tune in now:Ep 162 with Dr. Gabriele Kockelkoren #DrGPCR #GPCR #Biophysics #Pharmacology #DrugDiscovery #SciencePodcast | Dr. GPCR Ecosystem
Gabriele Kockelkoren shares: 🔬 How GPCR spatial organization shapes signaling and drug responses 🌍 Gabriele Kockelkoren #DrGPCR #GPCR #Biophysics #Pharmacology #DrugDiscovery #SciencePodcast Published GPCR Podcast 🎧 "You will always feel like you know nothing— and that’s completely fine." Gabriele Kockelkoren shares:🔬 How GPCR spatial organization shapes signaling and drug responses🌍 His Gabriele Kockelkoren #DrGPCR #GPCR #Biophysics #Pharmacology #DrugDiscovery #SciencePodcast Recent Articles
- Did you know that GPR20, a potential therapeutic target to treat gastrointestinal stromal tumours, performs high constitutive activity when coupling with Gi? Check out this paper to see how molecular dynamics simulation can be used to explore its constitutive activation mechanism. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/exploring-the-constitutive-activation-mechanism-of-the-class-a-orphan-gpr20 #gpcr #drgpcr | Dr. GPCR Ecosystem
Check out the latest GPCR news in the Ecosystem today! receptor-activation-and-signaling/exploring-the-constitutive-activation-mechanism-of-the-class-a-orphan-gpr20 #gpcr #drgpcr Published on February 13, 2025 Category GPCR Weekly News Did you know that GPR20, a potential Check out the latest GPCR news in the Ecosystem today! receptor-activation-and-signaling/exploring-the-constitutive-activation-mechanism-of-the-class-a-orphan-gpr20 #gpcr
- Exploring the combination of molecular simulation, pharmacological assays, and NMR to reveal the molecular mechanism of biased activation at the vasopressin V2 receptor. Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! | Dr. GPCR Ecosystem
Did you know that we work hard to bring you the most recent GPCR News, weekly? Published on December 10, 2024 Category GPCR Weekly News Exploring the combination of molecular simulation Did you know that we work hard to bring you the most recent GPCR News, weekly? 2B-chemokine-ligands-show-g-protein-bias-over-%CE%B2-arrestin-recruitment-and-receptor-internalization-in-cxcr1-signalling #gpcr
- Ep 05 with Dr. Terry Hébert
GPCR Podcast << Back to podcast list Dr. Terry Hébert About this episode Dr. Much of his work is based on GPCR signaling in the context to cardiovascular diseases. Terry tells us about the importance of adapting, communicating, and being mindful of those around us. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling
- Ep 29 with Eleonora Comeo
GPCR Podcast << Back to podcast list Eleonora Comeo About this episode Eleonora Comeo is a doctoral candidate We sat down to chat about GPCRs, synthesizing labeled ligands, and her unique position that allows her to work with GPCR scientists on 2 continents. Eleonora Comeo on the web LinkedIn ResearchGate Pubmed Google Scholar Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.
- insights into g protein coupling preference from cryo em structures of gq bound PTH1R | Dr. GPCR Ecosystem
protein coupling preference from cryo em structures of gq bound PTH1R Published on July 14, 2025 Category GPCR Strategic implications for biased agonist design A critical advance for anyone working on class B1 GPCRs utm_content=buffer3b1fa&utm_medium=social&utm_source=twitter.com&utm_campaign=buffer #DrGPCR #GPCR #PTH1R
- Content and Conduct Policy | Dr. GPCR Ecosystem
GPCR Ecosystem and promote a positive online community. Content and Conduct Policy Dr. GPCR, Corp, LLC (“Dr. GPCR”) provides its Service to you through our websites referred to as Dr. GPCR, Ecosystem.DrGPCR.com, DrGPCR.com. Please note that Ecosystem.DrGPCR.com is specializes in GPCR and related subjects. GPCR conducts business Affiliate Policy Content and Conduct Policy Content Guidance Privacy Policy Terms
- Ep 83 with Dr. Jean-Philippe Pin
GPCR Podcast << Back to podcast list Dr. Jean-Philippe Pin About Dr. intracellular proteins; the regulation of GPCRs by both negative and positive allosteric modulators, and the asymmetric functioning of GPCR dimers. Jean-Philippe Pin on the web LinkedIn ResearchGate CNRS Fondation Bettencourt Schueller FRC Neurodon GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.
- Ep 156 with Dr. Justin English
GPCR Podcast << Back to podcast list Empowering Drug Discovery for the GPCR Community with Dr. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. . ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Recent Podcast Articles GPCR Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- How do GRK-specific phosphorylation barcodes influence β-arrestin binding to GPCRs? New cryo-EM structures from Chen et al. (Nature, 2025) reveal that β-arrestin1 and β-arrestin2 form distinct complexes with ACKR3 depending on whether it's phosphorylated by GRK2 or GRK5, shaping arrestin conformation, complex stability, and engagement mode. Surprisingly, arrestin’s finger loop didn’t dive into the receptor core. Instead, it latched onto the micelle surface, breaking canonical expectations. Also, β-arrestin2 lacks a membrane anchor, making it more dynamic — a potential clue to its functional specialization. These findings underscore how barcode location + arrestin isoform = unique signaling outcomes. open book Read the full study: Inside Out: Mapping GPCRs from Membrane Codes to Market Moves #GPCRs #Arrestin #ACKR3 #GRKs #CryoEM #StructuralBiology #SignalingBias #Phosphorylation #DrGPCR | Dr. GPCR Ecosystem
Home → Flash News → How do GRK-specific phosphorylation barcodes influence β-arrestin binding to GPCRs + arrestin isoform = unique signaling outcomes. open book Read the full study: Inside Out: Mapping GPCRs from Membrane Codes to Market Moves #GPCRs #Arrestin #ACKR3 #GRKs #CryoEM #StructuralBiology #SignalingBias barcodes influence β-arrestin binding to GPCRs? Read the full study: Inside Out: Mapping GPCRs from Membrane Codes to Market Moves #GPCRs #Arrestin #
- Ep 28 with Dr. Ross Cheloha
GPCR Podcast << Back to podcast list Dr. Ross Cheloha About this episode Dr. Ross Cheloha on the web NIDDK Cheloha Lab Google Scholar LinkedIn Twitter ResearchGate Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- ⚠️Registration Deadline today! This is your last chance to register for “The Practical Assessment of Signaling Bias” with Dr. Terry Kenakin. Learn theoretical background for the techniques and apply with hands-on exercises 💪 ✳️Last chance!!! https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr GPCR Courses ⚠️ Registration Deadline today! https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr
- Started in medicinal chemistry. Got hooked on ligand design. Dr. Maria Majellaro didn’t plan to run a biotech company. A thesis project, a mentor’s advice, and a leap during the pandemic changed everything. Now she’s leading Celtarys, building custom fluorescent probes, and partnering with Dr. GPCR to support assay development worldwide. Meet Celtarys and learn more about its leading work on ligand-linker-fluorophore chemistry 🚀 ✳️ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-168-with-dr.-maria-majellaro-from-celtarys #GPCRcommunity #DrGPCR #FluorescentLigands #GPCRdrugDiscovery #ScientificLeadership #BiotechInnovation | Dr. GPCR Ecosystem
GPCR to support assay development worldwide. leading work on ligand-linker-fluorophore chemistry 🚀 ✳️ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast GPCR Podcast Started in medicinal chemistry. Got hooked on ligand design. Dr. GPCR to support assay development worldwide. leading work on ligand-linker-fluorophore chemistry 🚀 ✳️ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast
