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Showcase your creativity in the AGPCR24 Logo Contest! Submit your design to represent the Adhesion GPCR Workshop and inspire our global community. LOGO CONTEST Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Register Rules for the logo contest Design must be based on “Alebrijes” [ah-leh-bree-hez], which are chimeric creatures from Mexican folklore AND contain adhesion GPCRs Avoid copyrighted material unless a CC BY / open-use license has been acquired or generated (Adobe Stock, etc). The Consortium must be free to use the design. Requirements: Resolution 300 ppi max, JPEG/TIFF/EPS/PNG/PDF formats, 5MB max Open to all adhesion GPCR community members. Artist-scientists must be registered to attend the adhesion GPCR workshop 2024 in Mexico City. The contest deadline is August 15th, 2024, 11:59 PM CST (designs received after the deadline will not be considered) Designs or inquiries should be sent to this email The prize for the selected design will include free registration and more! Register for the Adhesion GPCR 2024 Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR workshop 2024 and its preliminary program. Up About the venue Discover Cinvestav, the host venue for the upcoming workshop. Up Abstract Submission Submit your research abstracts following our guidelines to present at the conference. Up Traveling Tips Find essential tips about Mexico City, including transportation options and local insights.

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Plenary Lecture Identification and Functional Characterization of Adhesion GPCRs As Steroid Hormone Receptors and Hearing and Balance Receptors Abstract Only Available for AGPCR24 Attendees About Jin-Peng Sun "Since starting my laboratory in 2011, I has focused on G protein coupled receptors, in particular, the ligand identification, physiological functions and molecular mechanism of biased signaling of GPCRs. Our first main research aspect is the identification of endogenous ligand of GPCRs. We have identified the receptor subfamily to sense the steroid hormones. For instance, membrane receptor GPR97 is able to sense glucocorticoid to mediate its rapid actions, the progesterone and 17-hydroxyprogesterone membrane receptor are GPR126. We also identified DHEA, DHEAS and DOC are endogenous ligands of GPR64 etc (Nature, 2021a, Nat Chem Biol 2022, PNAS 2022b). Our second main research aspect is dissecting the molecular mechanism underlying sensation of force, ordor, itch and taste by GPCRs. We have elucidated the mechanism of receptors' perception of itch, olfactory and force (Nature 2021b, 2022a, 2022b, 2023a, 2024). Our third main research aspect is working mechanism of GPCR. For arrestin mediated biased signaling, we have proposed the “flute model” and “poly proline region docking theory” etc. to explain the arrestin mediated GPCR functions (Nature communications, 2015, 2021, 2022; PNAS 2021, Molecular Pharmacology, 2017; Recommended by Faculty 1000, Nature Chemical Biology 2018). We identified that arrestin can mediated AT1R/TRPC3 or M3R/TRPC3 coupling by forming a complex of AT1R/β-arrestin-1/PLCγ/TRPC3 or M3R//β-arrestin-1/TRPC3 (Nature communications, 2017, Nature communications, 2018). We also identified that orphan receptor GPR64 forms complex with β-arrestin-1 and CFTR at apical membrane of efferent ductulus to regulate the salt/water metabolism (eLife 2018, Faculty 1000 recommendation). Our fourth main research aspect is ligand coding mechanisms and structural aided drug discovery of GPCR. We have decoded the mechanisms underlying recognition of fish oil (unsaturated fatty acids) and other lipids by GPCRs (Science 2023, Science Advance 2021, PNAS 2023, Nature Metabolism 2023), recognition of amine containing hormones by GPCRs (Cell 2021, 2023, Nature 2023b), bile acids or its derivatives by GPCRs (Nature 2020)." Jin-Peng Sun on the web Google Scholar LinkedIn < Previous Session Next Session >

Your go-to guide for attending AGPCR24. Find essential travel information, from transportation and accommodation tips to local insights, to help you make the most of your trip and enjoy a smooth, stress-free conference experience. TRAVELING TIPS Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Register DO's and DONT's for travelers in Mexico Mexico travel advice *Travelers are encouraged to consult their country's embassy advisories as they may differ from the one posted above. The Canadian embassy provides a comprehensive list. We highly suggest reserving accommodations in the city's center as the housing around the venue is scarce, and some may not be suitable for a convenient stay. Do not hesitate to contact us if you have inquiries regarding the neighborhood of your choice. We suggest the following neighborhoods: Roma Norte, Juárez, Zona Rosa, Condesa, Cuauhtémoc, San Rafael Apart from the numerous Airbnb options in these neighborhoods, here are our recommendations for affordable hotels in order of preference: 1. Hotel Carlota : An industrial chic experience at economical pricing. It can include breakfasts. 2. Hotel Exe Suites Reforma 3. Hotel Maria Cristina : Old School “hacienda”-type hotel. 4. Hotel Laila 5. City Express by Marriott EBC Reforma 6. Hoteles PF Zona Rosa MAP AIR TRAVEL Mexico City is accessible by two major airports. Transportation options, approximate travel times, and approximate fares to and from the airports are listed. Fares are subject to change. Airfare and other travel arrangements are the full responsibility of aGPCR Workshop 2024 attendees. Aeropuerto Internacional de la Ciudad de México (AICM) Benito Juárez is located 15 km from the “Angel de la Independencia” and 13 km from Cinvestav. This airport is the best option for international travel. Time/Distance : Approximate 35-minute drive. Taxis : Taxis are available at the lower levels (outside of baggage claim) at each terminal. Fares are based on traffic conditions, but an average fare is $20-$30. Subway : The subway is only available at Terminal 1. If your flight arrives at Terminal 2, there is a shuttle to Terminal 1. At the subway station you can purchase a “Movilidad Integrada” card in order to access public transportation (subway, metrobus, bikes, bus, etc). Information from public transportation can be followed through Google Maps or City Mapper apps. Uber and Didi apps : Uber type applications are available in Mexico City and a safe option for transportation. Aeropuerto Internacional Felipe Ángeles (AIFA) is located 53 km from the “Angel de la Independencia” and 33 km from Cinvestav. Time/Distance : Approximate 60-minute drive. Taxis : Taxis are available at the lower levels (outside of baggage claim) at each terminal. Fares are based on traffic conditions, but an average fare is $30-$50. Public Transportation : We recommend taking a shuttle (available for travelers) from AIFA to AICM Terminal 1. TRAVEL & VISA INFORMATION We look forward to welcoming attendees. Please check if you need a visa or permit to enter Mexico. After identifying that a visa or permit is needed, foreign travelers should contact their country's Mexican Embassy Consular Section. To request a Letter of Invitation for visa purposes, contact us. MONEY EXCHANGE Mexican pesos are the currency of Mexico. Reliable exchange booths are available at airports, banks, and hotels. However, many businesses accept credit/debit cards. POSTER PRINTING Poster printing is the full responsibility of aGPCR Workshop 2024 attendees. Office Depot and Office Max offer services for poster printing. Close to Cinvestav, on “Instituto Politécnico Nacional” avenue, there are several small local businesses offering poster printing services. The average fare for poster printing is $10-$12. SIM CARD AND WIFI SIM cards can be easily purchased at the airport and Oxxo stores around the city. The average fare is $10-$12. Public Wi-Fi is available around the city, including at airports and subway stations, and just outside of Cinvestav. FOOD RESTRICTIONS Please share any food restrictions you might have (allergies, dietary, etc). We will try to accommodate you as best we can. GETTING TO THE VENUE UBER is the most recommended as it is a highly economical and safe way to reach Cinvestav from your housing accommodation. We recommend carpooling with others to reduce individual costs and to be environmentally friendly. Typical costs are $8 USD one way ($2 USD / person carpooling with four people). Register for the Adhesion GPCR 2024 Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR workshop 2024 and its preliminary program. Up About the venue Discover Cinvestav, the host venue for the upcoming workshop. Up Abstract Submission Submit your research abstracts following our guidelines to present at the conference. Up Logo Contest Enter our logo contest for a chance to have your design represent the upcoming event.

Molecular Biochemis-try, Leipzig University, Johannisallee 30, D-04103 Leipzig" About Fabian Pohl "Mar Sträter Oct 2011 – Mar 2016 Master of Science in chemistry, University Leipzig Oct 2008 – Sep 2011 Bachelor

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Closing remarks < Previous Session Next Session >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Welcoming Remarks < Previous Session Next Session >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Complimentary Lunch < Previous Session Next Session >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Session VIII Physiological and pathological roles of AGPCRs in the periphery ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih Hsiao Adhesion GPCR GPR116/Adgrf5 controls a lineage of anti-thermogenic adipocytes with implications for adaptive thermogenesis during prolonged cold exposure Anastasia Georgiadi ADGRF5-mediated regulation of cardiac health and disease Douglas Tilley ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih Hsiao Abstract Only available for AGPCR 24 Attendees Authors & Affiliations "Cheng-Chih Hsiao1,2, Hendrik J. Engelenburg1, Joost Smolders1,3, and Jörg Hamann1,2 1Department of Neuroimmunology, Netherlands Institute for Neuroscience, Amsterdam, The Netherlands; 2Department of Experimental Immunology, Amsterdam institute for Immunology and Infectious diseases, Amsterdam University Medical Center, Amsterdam, The Netherlands; 3MS center ErasMS, Departments of Neurology and Immunology, Erasmus Medical Center, Rotterdam, The Netherlands" About Cheng-Chih Hsiao "2012-2015: PhD in Immunology, University of Amsterdam; 2015-2019: Postdoctoral researcher, Amsterdam UMC; 2019-2022: Senior postdoctoral researcher, Netherlands Institute for Neuroscience; 2022 - present: Researcher associate, Netherlands Brain Bank" Cheng-Chih Hsiao on the web LinkedIn ReseachGate Adhesion GPCR GPR116/Adgrf5 controls a lineage of anti-thermogenic adipocytes with implications for adaptive thermogenesis during prolonged cold exposure Anastasia Georgiadi Abstract Only available for AGPCR 24 Attendees Authors & Affiliations "El Merabhi Rabih1*, Karagiannakou Vasiliki1*, Kardinal Ronja2, Jäckstein Michelle3 Yvonne, Kumar Jha Ankush1, Krokidi Sissy Thodou1, Wachten Dagmar2, Heeren Jörg3, Herzig Stephan1, Georgiadi Anastasia1 *equal contributions , Institutions : 1. Institute for Diabetes and Cancer, Helmholtz Centre Munich, Germany, 2. Institute of Innate Immunity, University Hospital Bonn, University of Bonn, 3. Centre for Experimental Medicine, Institute for Biocehmistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf" About Anastasia Georgiadi "Head of Junior Group Endocrine Pharmacology, Institute of Diabetes and Cancer (IDC). Professional Background Since 2021 Group Leader, Institute for Diabetes and Cancer, Helmholtz Diabetes Centre, Munich 2018 - 2021 Project Team Leader, Institute for Diabetes and Cancer, Helmholtz Diabetes Centre, Munich 2015 - 2018 Postdoctoral fellow, Department of Adipose Tissue Biology, Institute for Diabetes and Cancer, Helmholtz Diabetes Centre, Munich 2012 - 2015 Postdoctoral fellow, Department of Cell and Molecular Biology, Karolinska Institute, Sweden" Anastasia Georgiadi on the web Endocrine Pharmacology Google Scholar ADGRF5-mediated regulation of cardiac health and disease Douglas Tilley Abstract Only available for AGPCR 24 Attendees About Douglas Tilley "Research in the Tilley laboratory focuses primarily upon aspects of GPCR regulation of cardiac function, inflammation and remodeling during HF or following acute cardiac injury. Much of this work centered on elucidating novel mechanisms by which β-adrenergic receptors impact cardiac structure and function, and has evolved to encompass their roles in regulating immune cell response to acute cardiac injury or chronic stress. Additionally, the lab has begun to investigate potential roles for previously unrecognized cardiac-expressed GPCRs in the regulation of physiologic/pathologic function in the heart in an effort to uncover novel therapeutic directions for HF, including adhesion GPCRs (AGPCRs). In all, research in the Tilley lab spans molecular pharmacology to pathophysiology studies focused primarily in the cardiovascular realm." Douglas Tilley on the web Lewis Katz School of Medicine at Temple University < Previous Session Next Session >

Explore sponsorship opportunities for the Adhesion GPCR Workshop 2024. Connect your organization with leading GPCR researchers and showcase your brand to the scientific community. SPONSORSHIP PROSPECTUS Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Sponsor We are delighted to present the sponsorship opportunities available for Adhesion GPCR Workshop 2024, a premier scientific meeting bringing together leaders and innovators in G Protein-Coupled Receptor (GPCR) biology. Adhesion GPCR Workshop 2024 will take place on October 23-25, 2024 at Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (known as Cinvestav) in Mexico City, offering a dynamic platform for knowledge exchange, collaboration, and networking. About the Adhesion GPCR Workshop 2024: Adhesion GPCR Workshop 2024 is a high-profile expert conference, attracting attendees from across the globe. Our agenda includes keynote presentations, panel discussions, workshops, and networking sessions covering the latest advancements and challenges in Membrane Receptor biology. This event provides an unparalleled opportunity for sponsors to showcase their commitment to scientific excellence and innovation. Audience Profile: Basic Scientists Academics Clinical Scientists Industry Professionals Health Professionals Policy Makers Students Why Sponsor Adhesion GPCR Workshop 2024? Align your brand with scientific excellence and innovation. Showcase your products, services, and research initiatives to a targeted audience. Enhance brand visibility and recognition among key stakeholders in the field. Network with leading professionals and decision-makers in the industry. Support the advancement of knowledge and collaboration within the scientific community. Sponsorship Opportunities Platinum Sponsor Exclusive recognition as the Platinum sponsor in all promotional materials. Prime placement of company logo on event website, signage, and marketing collateral. Opportunity to deliver opening remarks or introduce keynote speakers. Complimentary exhibition booth in a prominent location at the event venue. Recognition in press releases and media coverage. Complimentary registration for 3 representatives. Opportunity to be designated in print on the 1 st ever “aGPCR Excellence and Mentoring Award” Customized sponsorship package available upon request. Gold Sponsor Prominent recognition as a Gold sponsor in all promotional materials. Company logo displayed on event website, signage, and marketing collateral. Opportunity to sponsor a keynote session or panel discussion. Recognition during opening and closing remarks. Complimentary exhibition booth at the event. Complimentary registration for 2 representatives. Customized sponsorship package available upon request. Silver Sponsor Recognition as a Silver sponsor in all promotional materials. Company logo displayed on event website and signage. Opportunity to sponsor a workshop or networking session. Recognition during opening and closing remarks. Complimentary registration for 1 representative. Customized sponsorship package available upon request. Bronze Sponsor Recognition as a Bronze sponsor in all promotional materials. Company logo displayed on event website.Recognition during opening and closing remarks. Additional Sponsorship Opportunities: Networking Reception Sponsorship Conference Cup and T-Shirt Sponsorship Conference Bag Sponsorship Lanyard Sponsorship Coffee Break Sponsorship Customized Opportunities Available Contact us for sponsorship Register for the Adhesion GPCR 2024 Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR workshop 2024 and its preliminary program. Up About the venue Discover Cinvestav, the host venue for the upcoming workshop. Up Abstract Submission Submit your research abstracts following our guidelines to present at the conference. Up Traveling Tips Find essential tips about Mexico City, including transportation options and local insights.

Meet the sponsors who make the Adhesion GPCR Workshop 2024 possible, supporting global collaboration and innovation in GPCR research. Home Registration Full Agenda Venue Travel Tips Sponsors Special Issue on Adhesion GPCRs OUR SPONSORS Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Sponsor Us Platinum Sponsors Bronze Sponsors Collaborating partners Contact us for sponsorship Register for the Adhesion GPCR 2024 Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR workshop 2024 and its preliminary program. Up About the venue Discover Cinvestav, the host venue for the upcoming workshop. Up Abstract Submission Submit your research abstracts following our guidelines to present at the conference. Up Traveling Tips Find essential tips about Mexico City, including transportation options and local insights.

Scott Leiser on the web University of Michigan Pubmed ResearchGate LinkedIn Dr.

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Leaving for City Center Coming Soon < Previous Session Next Session >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Leave for dinner reception Coming Soon < Previous Session Next Session >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Complimentary Reception dinner MENU Four Mushroom Soup Tomato, Panela Cheese, and Spinach tower with Oregano Vinaigrette Cane Sugar and Arbol Chile Lacquered Duck Monte Cristo Chocolate Cake Coffee or Tea Vegetarian option* -Mushroom-stuffed chiles on refried bean sauce- instead of the duck < Previous Session Next Session >

Sexton is also a co-founder of Septerna Inc. " Patrick Sexton on the web CCeMMP Monash University Dr.

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Coffee Break with lights snacks Complimentary < Previous Session Next Session >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Registration & Coffee with light breakfast < Previous Session Next Session >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Board meeting/General assembly Welcome to Join Coming Soon < Previous Session Next Session >

Dr. Keyword Cloud GPCR research community , Dr. Dr.

The Ramsey Lab Amy Ramsey on the web University of Toronto Pubmed Google Scholar LinkedIn Twitter Dr.

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Mexico City Nocturnal Tour, Food and drinks Coming Soon < Previous Session Next Session >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Coffee Break with pastries announcement of the aGEM award Complimentary < Previous Session Next Session >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Session IX / Technology capsule: Light on aGPCR signaling and function NovoiSMART - A new platform for GPCR antibody drug discovery Abstract Developing monoclonal antibody drugs against GPCRs and other multi-pass transmembrane targets, such as ion channels, remains a significant challenge. Novoprotein developed a NovoiSMART technology, utilizing mRNA-based immunization, which can overcome these obstacles by producing high-quality antibodies that more accurately mimic natural protein structures. This approach contrasts with other antigen forms like peptides or DNA, which face limitations in structural integrity and immunogenicity. mRNA technology, demonstrated in the success of COVID-19 vaccines, is emerging as a promising method for antibody discovery. Several case studies of GPCR and other multi-pass transmembrane targets are presented, including GPRC5D, Claudin 6 and Napi2b. These studies show that mRNA immunization yields higher antibody titers and greater epitope diversity compared to other methods. These examples underscore the potential of NovoiSMART technology in developing highly specific antibodies for complex targets, with implications for overcoming challenges like drug resistance and tumor escape. About Gavin Zhang Gavin is a currently a director of business and operations at Novoprotein Scientific. His research experience includes phylogenetics and cancer epigenetics. Gavin Zhang on the web LinkedIn < Previous Session Next Session >

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