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Results found for "fluorescent ligands"
- Trainee Symposium II
protein engineering, receptor pharmacology, and structural biology to study how different types of ligands
- The GPCR world is waiting to see YOU. Update your profile today and be part of the biggest GPCR community in the world 🌏 ✳️Visit https://www.ecosystem.drgpcr.com/account/my-account and share your updated information 😉 #gpcr #drgpcr | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep.166 of the Dr.GPCR Podcast,. The catch? It’s all about understanding the system, not replacing it. From neuromas to novel modulators, this episode is full of breakthroughs that matter for patients. 📲 Watch now: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- From aspiring doctor to GPCR scientist! 🔬In this episode, Ian Chronis shares his journey from med school dreams to a PhD in pharmacology, diving into the fascinating world of receptor signaling. Can you guess what’s his favorite GPCR? ✅ Hear his response: Ep 164 with Dr. Ian Chronis #SciencePodcast #GPCR #PhDLife #DrGPCR | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- In case you haven’t heard, Dr. Terry Kenakin will soon start the course Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection 📖 The five-lecture series describes essential additional elements to GPCR discovery programs that extend the discovery process and increase therapeutic opportunity. | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- What do you want to learn today? If you’re an Ecosystem Member, you can learn something new every day! 🚀 Take one of our courses On-Demand and expand your knowledge of GPCRs. ✳️Discover your next learning experience at https://www.ecosystem.drgpcr.com/gpcr-courses #gpcr #drgpcr | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- Unlock the full potential of the Dr. GPCR platform by updating your profile 🧬 Find like-minded scientists, and colleagues who work on the same topic as you 🙌 ✳️Go to https://www.ecosystem.drgpcr.com/account/my-account and update your profile #gpcr #drgpcr | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- What do GPCRs, acidic endosomes, and cancer immunotherapy have in common? Find out in our latest episode featuring Ian Chronis, where we explore the surprising ways GPR65 signals in different environments! ✅ Tune in: https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- Forget one receptor at a time. Go big.Ep.167 of the Dr.GPCR Podcast with Tom Sakmar & Ilana Kotliar is about scaling GPCR research with multiplexing, miniaturization, and collaboration. The tools are built. The data is free. What will you ask next? 📲 Dive in: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRtraining #GPCRresearchcommunity #DrGPCR #GPCRdata | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- Ready to stand out in the GPCR world? Take advantage of a platform where you can network within your field! 🌍 Showcase your expertise by keeping your profile up-to-date on Dr. GPCR. | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- Did you know registrations are already open for all our 2025 Dr.GPCR University Courses? Check out what you can learn this year from the master, Dr. Terry Kenakin 😉and save your spot soon! Remember Premium Members get a 25% discount 🙌 ✳️Click here and start your next learning experience https://www.ecosystem.drgpcr.com/gpcr-courses #gpcr #drgpcr | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- Can we preserve opioid pain relief without the side effects? 🔬 On Ep.166 of the Dr.GPCR Podcast, Ben Clements shares how positive allosteric modulators (PAMs) at the mu-opioid receptor could revolutionize treatment —with a 10x boost in methadone efficacy. Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship. 🎧 Full episode: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- A large-scale analysis of GPCR molecular dynamics reveals hidden allosteric sites and lateral gateways, unlocking new possibilities for drug discovery. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/large-scale-investigation-of-gpcr-molecular-dynamics-data-uncovers-allosteric-sites-and-lateral-gateways #gpcr#drgpcr | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- Scientific careers are not just built on brilliance | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- "Solving financial puzzles feels just like solving scientific ones," says Joe St. Germain from Company Launch Partners. Behind every successful research organization, there is a rock-solid operations team. Don’t miss this rare conversation bridging science, structure, and strategy with Chuck DeWeese & Joe St. Germain. ✳️ Tune in now: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- A high-resolution deep mutational scan of MC4R reveals how thousands of genetic variants impact obesity-linked signaling pathways and highlights new opportunities for precision drug discovery Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr#drgpcr | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- A GPCR imaging breakthrough that didn’t start in a grant proposal | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- Weekly News October 16 | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- 📢 All 2025 Dr.GPCR Courses Are Open for Registration! Which one will you choose? 🚀 Whether you're diving into GPCR drug discovery, pharmacology, or advanced modeling, there's a course for you. 💡 Bonus: Premium Members enjoy 25% off on all courses! 🔗 Explore & register today: https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #Biotech #DrugDiscovery #Pharmacology | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- New biosensor technologies are shedding light on GPCR dynamics directly in cells, offering exciting possibilities for multiplexing and miniaturization! Curious about how these advances could impact drug discovery? Check out the latest review on GPCR biosensors. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- New Episode Alert! 🎙️ Ep. 163 of the Dr. GPCR Podcast is here! 🚀 This time, we sit down with Dr. Dmitry Veprintsev to discuss the importance of asking the right GPCR questions. Whether you're a researcher, student, or GPCR enthusiast, this episode is packed with insights that will challenge how you think about your experiments. ✳️Tune in at https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr.-dmitry- #DrGPCR #GPCRPodcast #Pharmacology #DrugDiscovery #Biotech #GPCRs | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- New cryo-EM insights reveal how extracellular domains communicate with transmembrane regions in holo-adhesion GPCRs, uncovering mechanisms behind receptor activation. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/adhesion-gpcrs/conformational-coupling-between-extracellular-and-transmembrane-domains-modulates-holo-adhesion-gpcr-function #gpcr #drgpcr | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- GPCRs regulate key biological processes, but how exactly do inhibitory Gαi proteins control signal transduction beyond adenylyl cyclase suppression? New research sheds light on these pathways! ✨ Want to learn more? Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- Did you know? 🌟 Researchers have developed reversibly photoswitchable allosteric modulators for Class A GPCRs! 🧬💡 These innovative compounds, “Photo-BQCisA” and “Photo-BQCtrAns,” offer subtype-selective precision by combining allosteric modulation with light control, paving the way for new therapeutic strategies targeting muscarinic receptors (M1-M5). 🔬✨ Learn more about this breakthrough in the Ecosystem! | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- Dr. John Janetzko | Dr. GPCR Ecosystem
techniques including various mass spectrometry approaches, single particle cryo-EM and single-molecule fluorescence
- Full Agenda for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Extracellular Region with Transmembrane Domain in a Holo-Adhesion GPCR Yuling Feng Localization of putative ligands Approach for Drug Discovery for Human Adhesion GPCRs Anne Bormann Intricacies Of Complex Assembly And Ligand
- Did you know that GPR20, a potential therapeutic target to treat gastrointestinal stromal tumours, performs high constitutive activity when coupling with Gi? Check out this paper to see how molecular dynamics simulation can be used to explore its constitutive activation mechanism. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/exploring-the-constitutive-activation-mechanism-of-the-class-a-orphan-gpr20 #gpcr #drgpcr | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- Ever wondered how we perceive bitterness? 👅🔬 Researchers have unveiled the cryo-EM structure of TAS2R14, the most promiscuous bitter taste receptor, bound to the drug flufenamic acid (FFA) and its signaling partner gustducin! 🌟 This discovery reveals an unusual dual binding mode of FFA and offers tools for site-targeted compound design. 🧪✨ Learn more about this exciting breakthrough in bitter taste signaling. | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- How GPCR Spatial Signaling Sparked a Scientific Journey | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
- 🔬 Enhance Your GPCR Expertise with Dr.GPCR University! Looking to sharpen your skills in GPCR pharmacology, drug discovery, data analysis, or project management? Dr.GPCR University offers industry-focused courses designed to help you stay ahead in the field. ✅ Comprehensive course library covering cutting-edge GPCR science ✅ Practical insights for real-world drug discovery challenges ✅ Flexible, on-demand learning to fit your schedule 🚀 Elevate your expertise today: Start learning now #GPCR #Pharmacology #DrugDiscovery #Biotech #DrGPCR | Dr. GPCR Ecosystem
Experiments: How to Avoid the Most Common Data Pitfalls Binding affinity appears straightforward: add ligand
