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- Dr. Lauren M. Slosky | Dr. GPCR Ecosystem
understand how the principles of receptor allosterism and functional selectivity can be leveraged in the development
- terrys corner from data to insight | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- A complete profile = a complete YOU. Highlight your publications, skills, and interests to connect with the right people! ✳️Go to https://www.ecosystem.drgpcr.com/account/my-account and update your profile on the Dr.GPCR. #gpcr #drgpcr | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- Donate to Dr GPCR — Support the GPCR Community & University
Together, we can accelerate GPCR discoveries and develop more effective drugs for everyone. 👉 Donate
- The GPCR world is waiting to see YOU. Update your profile today and be part of the biggest GPCR community in the world 🌏 ✳️Visit https://www.ecosystem.drgpcr.com/account/my-account and share your updated information 😉 #gpcr #drgpcr | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep.166 of the Dr.GPCR Podcast,. The catch? It’s all about understanding the system, not replacing it. From neuromas to novel modulators, this episode is full of breakthroughs that matter for patients. 📲 Watch now: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- From aspiring doctor to GPCR scientist! 🔬In this episode, Ian Chronis shares his journey from med school dreams to a PhD in pharmacology, diving into the fascinating world of receptor signaling. Can you guess what’s his favorite GPCR? ✅ Hear his response: Ep 164 with Dr. Ian Chronis #SciencePodcast #GPCR #PhDLife #DrGPCR | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- In case you haven’t heard, Dr. Terry Kenakin will soon start the course Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection 📖 The five-lecture series describes essential additional elements to GPCR discovery programs that extend the discovery process and increase therapeutic opportunity. | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- What do you want to learn today? If you’re an Ecosystem Member, you can learn something new every day! 🚀 Take one of our courses On-Demand and expand your knowledge of GPCRs. ✳️Discover your next learning experience at https://www.ecosystem.drgpcr.com/gpcr-courses #gpcr #drgpcr | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- Unlock the full potential of the Dr. GPCR platform by updating your profile 🧬 Find like-minded scientists, and colleagues who work on the same topic as you 🙌 ✳️Go to https://www.ecosystem.drgpcr.com/account/my-account and update your profile #gpcr #drgpcr | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- What do GPCRs, acidic endosomes, and cancer immunotherapy have in common? Find out in our latest episode featuring Ian Chronis, where we explore the surprising ways GPR65 signals in different environments! ✅ Tune in: https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- Forget one receptor at a time. Go big.Ep.167 of the Dr.GPCR Podcast with Tom Sakmar & Ilana Kotliar is about scaling GPCR research with multiplexing, miniaturization, and collaboration. The tools are built. The data is free. What will you ask next? 📲 Dive in: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRtraining #GPCRresearchcommunity #DrGPCR #GPCRdata | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- Ready to stand out in the GPCR world? Take advantage of a platform where you can network within your field! 🌍 Showcase your expertise by keeping your profile up-to-date on Dr. GPCR. | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- GPCR CRO Bank | Dr. GPCR Ecosystem
. 🤝 Build Trust Develop content that speaks their language and establishes your credibility in the GPCR
- Dr. Khaled Abdelrahman, Victoria Rasmussen and Madelyn Moore | Dr. GPCR Ecosystem
During her time at Providence College, she received the Walsh Grant Fellowship to develop novel methods
- New biosensor technologies are shedding light on GPCR dynamics directly in cells, offering exciting possibilities for multiplexing and miniaturization! Curious about how these advances could impact drug discovery? Check out the latest review on GPCR biosensors. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- Did you know registrations are already open for all our 2025 Dr.GPCR University Courses? Check out what you can learn this year from the master, Dr. Terry Kenakin 😉and save your spot soon! Remember Premium Members get a 25% discount 🙌 ✳️Click here and start your next learning experience https://www.ecosystem.drgpcr.com/gpcr-courses #gpcr #drgpcr | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- Can we preserve opioid pain relief without the side effects? 🔬 On Ep.166 of the Dr.GPCR Podcast, Ben Clements shares how positive allosteric modulators (PAMs) at the mu-opioid receptor could revolutionize treatment —with a 10x boost in methadone efficacy. Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship. 🎧 Full episode: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- A large-scale analysis of GPCR molecular dynamics reveals hidden allosteric sites and lateral gateways, unlocking new possibilities for drug discovery. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/large-scale-investigation-of-gpcr-molecular-dynamics-data-uncovers-allosteric-sites-and-lateral-gateways #gpcr#drgpcr | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- "Solving financial puzzles feels just like solving scientific ones," says Joe St. Germain from Company Launch Partners. Behind every successful research organization, there is a rock-solid operations team. Don’t miss this rare conversation bridging science, structure, and strategy with Chuck DeWeese & Joe St. Germain. ✳️ Tune in now: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- A high-resolution deep mutational scan of MC4R reveals how thousands of genetic variants impact obesity-linked signaling pathways and highlights new opportunities for precision drug discovery Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr#drgpcr | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- 📢 All 2025 Dr.GPCR Courses Are Open for Registration! Which one will you choose? 🚀 Whether you're diving into GPCR drug discovery, pharmacology, or advanced modeling, there's a course for you. 💡 Bonus: Premium Members enjoy 25% off on all courses! 🔗 Explore & register today: https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #Biotech #DrugDiscovery #Pharmacology | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- New Episode Alert! 🎙️ Ep. 163 of the Dr. GPCR Podcast is here! 🚀 This time, we sit down with Dr. Dmitry Veprintsev to discuss the importance of asking the right GPCR questions. Whether you're a researcher, student, or GPCR enthusiast, this episode is packed with insights that will challenge how you think about your experiments. ✳️Tune in at https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-163-with-dr.-dmitry- #DrGPCR #GPCRPodcast #Pharmacology #DrugDiscovery #Biotech #GPCRs | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- Generic tools won’t solve tomorrow’s drug discovery challenges. That’s why Celtarys designs custom fluorescent probes for every target, built for real pharmacology, not just convenience. With Dr. GPCR and Celtarys joining forces, expect more visibility, more precision, and more scientific impact. 🚀 Get to know our media partner: https://www.ecosystem.drgpcr.com/celtarys-research-dr-gpcr-ecosystem #GPCRdrugDiscovery #GPCRecosystem #CustomLigands | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- New cryo-EM insights reveal how extracellular domains communicate with transmembrane regions in holo-adhesion GPCRs, uncovering mechanisms behind receptor activation. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/adhesion-gpcrs/conformational-coupling-between-extracellular-and-transmembrane-domains-modulates-holo-adhesion-gpcr-function #gpcr #drgpcr | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- GPCRs regulate key biological processes, but how exactly do inhibitory Gαi proteins control signal transduction beyond adenylyl cyclase suppression? New research sheds light on these pathways! ✨ Want to learn more? Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- Dr. GPCR University is officially back! 🎆 Join Dr. Terry Kenakin for "The Practical Assessment of Signaling Bias" workshop! 🚀 Learn the practical issues with detecting, measuring, and quantifying GPCR ligand-biased signaling. ✳️Early Bird discounts for Premium Members! ➡️Register today at https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- A GPCR imaging breakthrough that didn’t start in a grant proposal | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- Weekly News October 16 | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
- Ever wondered how we perceive bitterness? 👅🔬 Researchers have unveiled the cryo-EM structure of TAS2R14, the most promiscuous bitter taste receptor, bound to the drug flufenamic acid (FFA) and its signaling partner gustducin! 🌟 This discovery reveals an unusual dual binding mode of FFA and offers tools for site-targeted compound design. 🧪✨ Learn more about this exciting breakthrough in bitter taste signaling. | Dr. GPCR Ecosystem
affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development
