Lighting up a native pancreatic islet isn’t just a technical win — it’s a shift in what GPCR imaging can reveal

Our latest Dr. GPCR blog breaks down the moment Dr. Johannes Broichhagen and David Hodson realized their fluorescent peptide probe could visualize GLP-1R across an entire intact islet — not in an overexpression system, but in real tissue.

This is the kind of advance that matters for anyone building tools, assays, or therapeutics around receptor biology:

• Higher fidelity GPCR imaging without antibody variability

• Surface-pool selectivity — the pharmacologically relevant population

• Compatibility with live cells, tissue, and deep-imaging setups

• A design logic that extends to other GPCRs

Just as important: the collaboration model behind the science.Trust, interdisciplinary thinking, and a shared drive to build tools that actually work at the bench.

If your team relies on receptor visualization — discovery, screening, translational work — this story has strategic takeaways you’ll want to steal.

🔗 Read the blog : https://www.ecosystem.drgpcr.com/post/when-the-islet-lit-up-advancing-gpcr-imaging-in-native-tissue

#GPCR #DrGPCR #GPCRimaging #biotech #drugdiscovery