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Visualizing GPCRs in their native environment changes everything
Visualizing GPCRs in their native environment changes everything
Published on
December 2, 2025
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This week on The Dr. GPCR Podcast, we bring you Episode 2 of our three-part series with Celtarys Research — featuring chemist Dr. Johannes Broichhagen, whose work is redefining how we image GPCRs in real tissue.
His team’s chemical probes enabled high-resolution GLP-1R visualization across systems — from pancreatic islets to in vivo two-photon imaging.
Inside the episode:
Chemical probes vs antibodies: specificity, stability, and live-cell performance
Mapping GPCR surface pools with precision
Tissue-level insights reshaping metabolic disease research
What’s next: multiplex receptor labeling + AI-designed tools
If GLP-1R biology, receptor trafficking, or advanced imaging are part of your work, this conversation belongs on your radar.
🎧 Listen to Episode 2 → https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/chemical-probes-for-gpcr-imaging-and-internalization And stay tuned for Episode 3 with Celtarys.
#GPCR #DrGPCR #metabolism #GLP1R #receptorbiology #fluorescenceimaging #drugdiscovery
