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- Unveiling Non-Canonical Functions for Gαq Signaling Pathways
The research group led by Dr. located in the Centro de Biología Molecular “Severo Ochoa” (UAM/CSIC) and belongs also to the Health Research These results have been published in the journal Nature Communications (12 (1):4540, 2021) with the title GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- How does nanoscale GPCR organization shape signaling? 🤔 We explore this & more with Dr. Gabriele Kockelkoren, a physicist-turned-biologist with expertise in GPCR spatial dynamics. And if you wonder what his favorite GPCR could be, here’s the answer 😉 ✅Listen now Ep 162 with Dr. Gabriele Kockelkoren #gpcr #drgpcr | Dr. GPCR Ecosystem
Home → Flash News → How does nanoscale GPCR organization shape signaling? Gabriele Kockelkoren, a physicist-turned-biologist with expertise in GPCR spatial dynamics. Gabriele Kockelkoren #gpcr #drgpcr Published on March 20, 2025 Category Dr. GPCR Podcast How does nanoscale GPCR organization shape signaling? Gabriele Kockelkoren #gpcr #drgpcr Previous Next Recent Articles
- Dr. Channel | Dr. GPCR Ecosystem
Channel — your video hub for GPCR science, innovation, and community stories. Dr.
- What do GPCRs, acidic endosomes, and cancer immunotherapy have in common? Find out in our latest episode featuring Ian Chronis, where we explore the surprising ways GPR65 signals in different environments! ✅ Tune in: https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast | Dr. GPCR Ecosystem
Home → Flash News → What do GPCRs, acidic endosomes, and cancer immunotherapy have in common? ✅ Tune in: https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast Published on April 15, 2025 Category GPCR Podcast What do GPCRs, acidic endosomes, and cancer immunotherapy have in common? ✅ Tune in: https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast Previous Next Recent Articles
- Let’s connect the dots! Update your Dr. GPCR profile to make meaningful connections in the global GPCR network 🌐 ✳️Visit https://www.ecosystem.drgpcr.com/account/my-account and fill out the boxes with your most updated information. #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR profile to make meaningful connections in the global GPCR network 🌐 ✳️Visit https://www.ecosystem.drgpcr.com #gpcr #drgpcr Published on January 8, 2025 Category Dr. GPCR Profiles Let’s connect the dots! GPCR profile to make meaningful connections in the global GPCR network 🌐 ✳️Visit https://www.ecosystem.drgpcr.com #gpcr #drgpcr Previous Next Recent Articles
- Terry's Corner is Officially LIVE! 🎉 This is your new go-to for mastering drug discovery pharmacology. No fluff, just clear, on-demand insights from Terry Kenakin. Building core expertise? Master dose-response, binding, kinetics, and foundational models. Driving drug discovery? Apply pharmacology to selectivity, ADME, and strategic decision-making. An experienced drug hunter? Sharpen your edge with allosteric bias, residence time, and translational PK/PD. Learn on-demand, apply immediately: https://terrykenakin.com #DrGPCR #GPCR #pharmacology #TerrysCorner #DrugDiscovery | Dr. GPCR Ecosystem
Learn on-demand, apply immediately: https://terrykenakin.com #DrGPCR #GPCR #pharmacology #TerrysCorner GPCR Podcast 4 hours ago From Pipettes to Platforms: The Evolution of GPCR Research The first time Michelle GPCR Podcast 2 days ago How GPCR Spatial Signaling Sparked a Scientific Journey Michelle hadn’t mapped Yet that summer research placement cracked open a new reality: the thrill of asking questions no one GPCR News 5 days ago
- Interrogating Multiscale Receptors Functions in Space
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to Beaulieu was an associate professor and Canada Research Chair (Tier2) in the Department of Psychiatry In addition to basic research, the Beaulieu group is also actively implicated in translational research GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- Ever wondered how we perceive bitterness? 👅🔬 Researchers have unveiled the cryo-EM structure of TAS2R14, the most promiscuous bitter taste receptor, bound to the drug flufenamic acid (FFA) and its signaling partner gustducin! 🌟 This discovery reveals an unusual dual binding mode of FFA and offers tools for site-targeted compound design. 🧪✨ Learn more about this exciting breakthrough in bitter taste signaling. | Dr. GPCR Ecosystem
👅🔬 Researchers have unveiled the cryo-EM structure of TAS2R14, the most promiscuous bitter taste receptor Published on December 5, 2024 Category GPCR Weekly News Ever wondered how we perceive bitterness? 👅🔬 Researchers have unveiled the cryo-EM structure of TAS2R14 , the most promiscuous bitter taste receptor receptor-activation-and-signaling/a-bitter-anti-inflammatory-drug-binds-at-two-distinct-sites-of-a-human-bitter-taste-gpcr 3ecb-4719-8ba3-974d17e9f596&utm_source=so&utm_medium=mail&cid=79a6b35e-7ba6-44a0-863b-0842f5a5cfd3 #gpcr
- Contact | Dr. GPCR Ecosystem
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- Lighting up a native pancreatic islet isn’t just a technical win it’s a shift in what GPCR imaging can reveal | Dr. GPCR Ecosystem
A breakthrough in GPCR imaging reveals a full native pancreatic islet and advances how GLP-1R can be Flash News → Lighting up a native pancreatic islet isn’t just a technical win it’s a shift in what GPCR can reveal Lighting up a native pancreatic islet isn’t just a technical win — it’s a shift in what GPCR GPCR blog breaks down the moment Dr. #GPCR #DrGPCR #GPCRimaging #biotech #drugdiscovery Previous Next Recent Articles
- Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! Cutting-edge cryo-EM reveals how LYCHOS, a lysosomal protein, senses cholesterol to regulate metabolism and cell growth ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/cryo-em-reveals-cholesterol-binding-in-the-lysosomal-gpcr-like-protein-lychos #gpcr #drgpcr | Dr. GPCR Ecosystem
Home → Flash News → Check out the latest GPCR news in the Ecosystem today! metabolism and cell growth ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function /cryo-em-reveals-cholesterol-binding-in-the-lysosomal-gpcr-like-protein-lychos #gpcr #drgpcr Published on February 4, 2025 Category GPCR Weekly News Check out the latest GPCR news in the Ecosystem today! /cryo-em-reveals-cholesterol-binding-in-the-lysosomal-gpcr-like-protein-lychos #gpcr #drgpcr Previous
- Think βCGRP is just αCGRP’s understudy? Think again. New research shows that βCGRP triggers distinct receptor signaling profiles across the CGRP receptor family, challenging the long-held assumption of redundancy. 🔬 A closer look reveals differences in G protein coupling, second messenger production, and receptor trafficking. 📊 This could reshape how we understand CGRP-related physiology—and how we target it in drug design. 🧠 Pain, inflammation, metabolism: the implications go far beyond signaling bias. 🔗 Read the full paper in Biochemistry: Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors #GPCR #CGRP #DrugDiscovery #Pharmacology #SignalTransduction #Neuropeptides | Dr. GPCR Ecosystem
New research shows that βCGRP triggers distinct receptor signaling profiles across the CGRP receptor Read the full paper in Biochemistry: Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors #GPCR #DrugDiscovery #Pharmacology #SignalTransduction #Neuropeptides Published on June 16, 2025 Category GPCR New research shows that βCGRP triggers distinct receptor signaling profiles across the CGRP receptor Read the full paper in Biochemistry : Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors #GPCR
- Complimentary Lunch | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Closing remarks | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Welcoming Remarks | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- ⏳ In case you haven’t heard—registration for “Development of GPCR Ligands as Therapeutic Drugs” closes March 18th! If you’re working on GPCR drug discovery, you know that finding a promising candidate is just the start. A drug must also: ✅ Be absorbed into the body ✅ Reach the right target ✅ Stay long enough to be effective ✅ Cause no harm 📢 Spots are limited—register by March 18th! 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery | Dr. GPCR Ecosystem
👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery Published on March 10, 2025 Category GPCR Courses ⏳ In case you haven’t heard—registration for “Development of GPCR Ligands as Therapeutic 👉 Development of GPCR Ligands as Therapeutic Drugs | Dr. GPCR Ecosystem #GPCR #DrGPCR #Pharmacology #Biotech #DrugDiscovery Previous Next Recent Articles
- What do you want to learn today? If you’re an Ecosystem Member, you can learn something new every day! 🚀 Take one of our courses On-Demand and expand your knowledge of GPCRs. ✳️Discover your next learning experience at https://www.ecosystem.drgpcr.com/gpcr-courses #gpcr #drgpcr | Dr. GPCR Ecosystem
🚀 Take one of our courses On-Demand and expand your knowledge of GPCRs. ✳️Discover your next learning experience at https://www.ecosystem.drgpcr.com/gpcr-courses #gpcr #drgpcr GPCR Courses What do you want to learn today? 🚀 Take one of our courses On-Demand and expand your knowledge of GPCRs. ✳️Discover your next learning experience at https://www.ecosystem.drgpcr.com/gpcr-courses #gpcr #drgpcr
- State of the Art Talk | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda State of the Art Talk Adhesion GPCR in Mechanobiology Abstract Only Available
- Ready to stand out in the GPCR world? Take advantage of a platform where you can network within your field! 🌍 Showcase your expertise by keeping your profile up-to-date on Dr. GPCR. | Dr. GPCR Ecosystem
Home → Flash News → Ready to stand out in the GPCR world? GPCR. Published on December 11, 2024 Category Dr. GPCR Profiles Ready to stand out in the GPCR world? GPCR. ✳️Start today at https://www.ecosystem.drgpcr.com/account/my-account #gpcr #drgpcr Previous Next Recent
- Biased agonism at the GLP-1 receptor: from structure to animal models of disease
3rd / 11:05 AM Abstract Coming Soon About Patrick Sexton " Patrick Sexton is a NHMRC Senior Principal Research He is a leader in the study of GPCRs. He is a 2022 Clarivate Analytics Highly Cited Researcher in two disciplines: Pharmacology & Toxicology Society), Vane Medal (BPS), Gordon Hammes Lectureship Award (American Chemical Society) and the GSK Research 22nd GPCR Retreat Sponsored by
- Interaction with the cell adhesion molecule NEGR1 affects mGluR5 cell signalling
She returned to Brazil in 2010, when she founded her independent research group. Since then, Dr. Nowadays, her research group comprises four undergraduates, two M.Sc., and six Ph.D. students, as well She was able to have several grants approved in Brazil and abroad, which have granted her research group GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- GPCR activation is well-known to be a multi-step process. However, current molecular structures only capture the fully activated complex. Check out this paper to see how scientists combine different techniques to elucidate the intermediate GPCR-mini-Gαsβγ complex at 2.6 Å. Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/structure-and-function-of-a-near-fully-activated-intermediate-gpcr-g%CE%B1%CE%B2%CE%B3-complex #gpcr #drgpcr | Dr. GPCR Ecosystem
Home → Flash News → GPCR activation is well-known to be a multi-step process. ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/structure-and-function-of-a-near-fully-activated-intermediate-gpcr-g %CE%B1%CE%B2%CE%B3-complex #gpcr #drgpcr Published on February 11, 2025 Category GPCR Weekly News GPCR ➡️ https:// www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/structure-and-function-of-a-near-fully-activated-intermediate-gpcr-g %CE%B1%CE%B2%CE%B3-complex #gpcr #drgpcr Previous Next Recent Articles
- 🎧 Why Does GPCR Location Make All the Difference? GPCR location within the cell can change everything: function, pharmacology, and even drug response. In Ep.162 of the Dr.GPCR Podcast, Dr. Gabriele Kockelkoren dives into: 🔬 How GPCR trafficking shapes signaling outcomes 🚀 Career insights from the lab to the broader biotech world This episode is packed with knowledge for scientists, drug hunters, and anyone fascinated by GPCRs! 🎙️ Listen now https://buff.ly/fYZ1tSq #DrGPCR #GPCR #DrugDiscovery #Pharma #Biotech #SciencePodcast ✅ Tune in today! | Dr. GPCR Ecosystem
Home → Flash News → 🎧 Why Does GPCR Location Make All the Difference? GPCR location within the cell can change everything: function, pharmacology, and even drug response. Gabriele Kockelkoren dives into: 🔬 How GPCR trafficking shapes signaling outcomes 🚀 Career insights 🎙️ Listen now https://buff.ly/fYZ1tSq #DrGPCR #GPCR #DrugDiscovery #Pharma #Biotech #SciencePodcast GPCR Podcast 🎧 Why Does GPCR Location Make All the Difference?
- New biosensor technologies are shedding light on GPCR dynamics directly in cells, offering exciting possibilities for multiplexing and miniaturization! Curious about how these advances could impact drug discovery? Check out the latest review on GPCR biosensors. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! | Dr. GPCR Ecosystem
Check out the latest review on GPCR biosensors. Check out the latest GPCR news in the Ecosystem today! Check out the latest review on GPCR biosensors. Check out the latest GPCR news in the Ecosystem today! #GPCR #DrGPCR #biosensor Previous Next Recent Articles
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GPCR Ecosystem, ensuring transparency and protecting your rights. GPCR, Corp (“Dr. GPCR” or "DrGPCR") provides its Service (as defined below) to you through our websites referred to as GPCR, Ecosystem.DrGPCR.com , DrGPCR.com . GPCR reserves the right to modify these Legal Policies and Disclaimers from time to time without prior
- Trainee Symposium II
During my short academic journey, I was awarded the Young Investigator Transdisciplinary Research Award Currently, I am engaged in postdoctoral research in the laboratory of Dr. Scott Prosser. My primary research focus lies in gaining deeper insights into the structural mechanisms governing G GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- Adenosine A3 receptor has been proposed to have significant roles in metabolism and immune responses. Check out this study to understand how it affects metabolic dysfunction-associated steatotic liver progression. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://buff.ly/42b6ra3 #gpcr #drgpcr | Dr. GPCR Ecosystem
GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://buff.ly/42b6ra3 #gpcr #drgpcr Published on January 16, 2025 Category GPCR Weekly News Adenosine A3 receptor has been proposed GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https:// www.ecosystem.drgpcr.com a3ar-antagonism-mitigates-metabolic-dysfunction-associated-steatotic-liver-disease-by-exploiting-monocyte-derived-kupffer-cell-necroptosis-and-inflammation-resolution #gpcr
- This study adds a key piece to the puzzle of adhesion GPCR signaling. Understanding receptor-specific nuances, like the role of NTF cleavage, is crucial for decoding their functional outcomes. Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! ➡️https://www.ecosystem.drgpcr.com/adhesion-gpcrs/n-terminal-fragment-shedding-contributes-to-signaling-of-the-full-length-adhesion-receptor-adgrl3 #gpcr #drgpcr | Dr. GPCR Ecosystem
Home → Flash News → This study adds a key piece to the puzzle of adhesion GPCR signaling. Did you know that we work hard to bring you the most recent GPCR News, weekly? #gpcr #drgpcr Published on January 28, 2025 Category GPCR Weekly News This study adds a key piece to the puzzle of adhesion GPCR signaling. #gpcr #drgpcr Previous Next Recent Articles
- From aspiring doctor to GPCR scientist! 🔬In this episode, Ian Chronis shares his journey from med school dreams to a PhD in pharmacology, diving into the fascinating world of receptor signaling. Can you guess what’s his favorite GPCR? ✅ Hear his response: Ep 164 with Dr. Ian Chronis #SciencePodcast #GPCR #PhDLife #DrGPCR | Dr. GPCR Ecosystem
Home → Flash News → From aspiring doctor to GPCR scientist! Can you guess what’s his favorite GPCR? ✅ Hear his response: Ep 164 with Dr. GPCR Podcast From aspiring doctor to GPCR scientist! Can you guess what’s his favorite GPCR? ✅ Hear his response: Ep 164 with Dr. Ian Chronis #SciencePodcast #GPCR #PhDLife #DrGPCR Previous Next Recent Articles
- Science isn't always about eureka moments—sometimes it's about steady progress. In our latest Dr. GPCR Podcast episode, Ian Chronis shares his top aha moments, from learning the hard way about gel electrophoresis to discovering the hidden complexities of GPCR signaling. ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology | Dr. GPCR Ecosystem
GPCR Podcast episode, Ian Chronis shares his top aha moments, from learning the hard way about gel electrophoresis to discovering the hidden complexities of GPCR signaling. ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast GPCR Podcast Science isn't always about eureka moments—sometimes it's about steady progress. GPCR Podcast episode, Ian Chronis shares his top aha moments, from learning the hard way about gel electrophoresis to discovering the hidden complexities of GPCR signaling. ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast
