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Results found for "GPCR data platform"
- Think βCGRP is just αCGRP’s understudy? Think again. New research shows that βCGRP triggers distinct receptor signaling profiles across the CGRP receptor family, challenging the long-held assumption of redundancy. 🔬 A closer look reveals differences in G protein coupling, second messenger production, and receptor trafficking. 📊 This could reshape how we understand CGRP-related physiology—and how we target it in drug design. 🧠 Pain, inflammation, metabolism: the implications go far beyond signaling bias. 🔗 Read the full paper in Biochemistry: Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors #GPCR #CGRP #DrugDiscovery #Pharmacology #SignalTransduction #Neuropeptides | Dr. GPCR Ecosystem
Read the full paper in Biochemistry: Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors #GPCR #DrugDiscovery #Pharmacology #SignalTransduction #Neuropeptides Published on June 16, 2025 Category GPCR Read the full paper in Biochemistry : Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors #GPCR
- Ep 125 with Dr. Gregory Tall
GPCR Podcast << Back to podcast list Dr. Gregory Tall About Dr. Gregory Tall " Dr. family or Family B2 GPCRs. We found that adhesion GPCRs are activated by a tethered peptide agonist mechanism that differed from Adhesion GPCRs pre-cleave themselves and the two resultant fragments of the receptor remain together GPCR Enjoying the Dr. GPCR Podcast? Leave a Review.
- Unveiling Non-Canonical Functions for Gαq Signaling Pathways
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Unveiling Non-Canonical Functions for Gαq Signaling Pathways Date & Time Friday, November 3rd Ribas continued working on the regulation of GPCR. The group of Dr. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- Ep 20 with Dr. Jennifer Pluznick
GPCR Podcast << Back to podcast list Dr. Jennifer Pluznick About this episode Dr. Her research is focused on the role of chemosensory GPCRs in regulating renal and cardiovascular function GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 10 with Dr. John Streicher
GPCR Podcast << Back to podcast list Dr. His encounter and interest in signaling in the context of GPCRs during his postdoctoral training in Dr GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 118 with Dr. David Sykes
GPCR Podcast << Back to podcast list Dr. David Sykes About Dr. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. . ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Recent Podcast Articles GPCR Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 04 with Dr. Graciela Pineyro
GPCR Podcast << Back to podcast list Dr. Graciela Pineyro About this episode Dr. Graciela Pineyro’s love for GPCR pharmacology started in Uruguay where she first worked on the serotonin GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 134 with Dr. Neil Grimsey
GPCR Podcast << Back to podcast list Dr. Neil Grimsey About Dr. Neil Grimsey " During my postdoctoral studies at USCD, I discovered a novel GPCR-dependent atypical kinase GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Biased agonism at the GLP-1 receptor: from structure to animal models of disease
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Biased agonism at the GLP-1 receptor: from structure to animal models of disease Date & Time He is a leader in the study of GPCRs. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- Closing Remarks. Lunch and farewell
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to Lunch and farewell Date & Time Saturday, November 4th / 12:30 PM Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- Welcome Reception and Poster Session 1
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Welcome Reception and Poster Session 1 Date & Time Thursday, November 2nd / 5:30 PM Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- Registration
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Registration Date & Time Thursday, November 2nd / 11:00 AM - 1:30 PM Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored
- Ep 121 with Yao Lu (Jackie)
GPCR Podcast << Back to podcast list Yao Lu (Jackie) About Yao Lu (Jackie) "Jackie is a Ph.D. student GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. . ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Recent Podcast Articles GPCR Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 158 with Dr. Mikel Garcia-Marcos
GPCR Podcast << Back to podcast list Anything BUT GPCRs with Dr. Mikel Garcia-Marcos About Dr. AI Summary In the podcast episode "Anything but GPCRs" featuring Dr. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 42 with Dr. Randy Hall
GPCR Podcast << Back to podcast list Dr. Randy Hall About Dr. Randy’s lab has a special interest in studying disease-associated mutations to human GPCRs that perturb Join me to learn more about Randy’s work, hear his insights on the GPCR field, and also hear the story GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling
- Ep 54 with Dr. JoAnn Trejo
GPCR Podcast << Back to podcast list Dr. JoAnn Trejo About Dr. JoAnn Trejo Dr. the guidance of Professor Shaun Coughlin where she worked on the newly discovered protease-activated GPCRs PARs are GPCRs that are activated through an atypical irreversible proteolytic mechanism. Discovering new aspects of PAR signaling is important for increasing the fundamental knowledge of GPCR GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.
- Ep 113 with Dr. Prasenjit Saha
GPCR Podcast << Back to podcast list Dr. Prasenjit Saha About Dr. Specifically, I am interested in understanding dysregulated G-protein coupled receptor (GPCR) signaling My long-term plan is to conduct research in the field of receptor biology, with a focus on GPCRs. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling
- Ep 126 with Dr. Françoise Bachelerie
GPCR Podcast << Back to podcast list Dr. Françoise Bachelerie About Dr. Paris-Saclay University with expertise in immunology and virology related to Host/Virus interactions and GPCR GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 34 with Dr. Brian Arey
GPCR Podcast << Back to podcast list Dr. He continues to pioneer in drug discovery studying GPCRs and other target classes. I sat down with Brian to chat about GPCRs, working in the industry, and being a leader. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling
- Ep 35 with Dr. Brian Arey
GPCR Podcast << Back to podcast list Dr. He continues to pioneer in drug discovery studying GPCRs and other target classes. I sat down with Brian to chat about GPCRs, working in the industry, and being a leader. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling
- Ep 63 with Dr. Khaled Abdelrahman
GPCR Podcast << Back to podcast list Dr. Khaled Abdelrahman About Dr. Khaled Abdelrahman Dr. He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 143 with Dr Davide Calebiro
GPCR Podcast << Back to podcast list Dr. Davide Calebiro About Dr. , engineers and computer scientists focusing on the basic mechanisms of G protein-coupled receptor (GPCR His major scientific contributions include the discovery that GPCRs are not only active at the plasma GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling
- Structure-based discovery of functionally selective 5-HT1A receptor agonists
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to Peter Gmeiner has been spokesman of the Research Training Group "Medicinal Chemistry of Selective GPCR GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by
- Ep 08 with Dr. Graciela Pineyro
GPCR Podcast << Back to podcast list Dr. Graciela Pineyro About this episode: Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. . ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Recent Podcast Articles GPCR Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 97 with Robert Laprairie
GPCR Podcast << Back to podcast list Robert Laprairie About Dr. Robert Laprairie Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. . ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Recent Podcast Articles GPCR Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 135 with Dr. Katarzyna Marcinkiewicz
GPCR Podcast << Back to podcast list Dr. Katarzyna Marcinkiewicz About Dr. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. . ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Recent Podcast Articles GPCR Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 77 with Martin Audet
GPCR Podcast << Back to podcast list Martin Audet About Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. . ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Recent Podcast Articles GPCR Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 55 with Mark Schmeizl
GPCR Podcast << Back to podcast list Mark Schmeizl About Mark Schmeizl Mark leverages 30 years in various GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. . ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Recent Podcast Articles GPCR Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 119 with Tanishka S. Saraf
GPCR Podcast << Back to podcast list Tanishka S. Saraf About Tanishka S. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. . ★ Review on Apple Podcasts ★ Rate on Spotify ✉️ Send feedback to the team Recent Podcast Articles GPCR Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
- Ep 128 with Dr. Ilana Kotliar
GPCR Podcast << Back to podcast list Dr. Ilana Kotliar About Dr. Ilana uses chemical biology-based methods to study the regulation and protein-protein interactions of GPCRs GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. Collaboration: From Models to Medicine Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox From Failed Experiments to Predictive GPCR Models Thanks for listening to this podcast episode
