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- ep 169 with sokhom pin some 2 | Dr. GPCR Ecosystem
GPCR Podcast Build the team you always wished you had. At Alkermes, Sokhom S. It was leadership. âłď¸ Watch Ep. 169: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-169-with-dr-sokhom-pin
- Terms and Conditions | Dr. GPCR Ecosystem
GPCR Ecosystem. Explore our Terms and Conditions page now! Terms and Conditions Dr. GPCR, Corp (âDr. GPCRâ) provides its Service to you through our websites referred to as Dr. GPCR, Ecosystem.DrGPCR.com, DrGPCR.com. 1. GPCR, Corp (âDr. GPCR, Corp (âDr. GPCRâ) may change this ATS from time to time without prior notice.
- Weekly News October 16 | Dr. GPCR Ecosystem
Home â Flash News â Weekly News October 16 Published on October 16, 2025 Category GPCR Weekly News Enzymes #DrGPCR #GPCR Previous Next Recent Articles
- Partners Submition Form | Dr. GPCR Ecosystem
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- Some biotech stories start in the lab. Celtarys started with a thesis project, a new chemical strategy, and a vision to make fluorescence available for drug discovery. Now, theyâre growing fast and partnering with Dr. GPCR to connect with the researchers who need them most. âłď¸ Learn more about the partnership: https://www.ecosystem.drgpcr.com/celtarys-research-dr-gpcr-ecosystem #GPCRcommunity #ScienceCollaboration #FluorescentLigands #BiotechStartup | Dr. GPCR Ecosystem
GPCR to connect with the researchers who need them most. âłď¸ Learn more about the partnership: https:/ /www.ecosystem.drgpcr.com/celtarys-research-dr-gpcr-ecosystem #GPCRcommunity #ScienceCollaboration #FluorescentLigands GPCR to connect with the researchers who need them most. âłď¸ Learn more about the partnership: https:/ /www.ecosystem.drgpcr.com/celtarys-research-dr-gpcr-ecosystem #GPCRcommunity #ScienceCollaboration #FluorescentLigands
- Content Guidelines | Dr. GPCR Ecosystem
GPCR Ecosystem website. Get the information you need to create engaging and impactful content. GPCR, Corp, LLC (âDr. GPCRâ) provides its Service to you through our websites referred to as Dr. GPCR, Ecosystem.DrGPCR.com, DrGPCR.com. Please note that Ecosystem.DrGPCR.com is specializes in GPCR and related subjects. GPCR conducts business Affiliate Policy Content and Conduct Policy Content Guidance Privacy Policy Terms
- đ¨ Exciting Opportunity for Professionals in Drug Development! đ¨ Register today for a one-of-a-kind online course at Dr. GPCR University: "Development of GPCR Ligands as Therapeutic Drugs." đ Dates: March 20 - April 10, 2025 â° Time: Thursdays, 10:00 AM - 11:30 AM (EST) This advanced course is essential for anyone working in drug development and focuses on: The essentials of new drug development Key pharmacokinetic elements (absorption, distribution, clearance) Hepatic metabolism and the Cytochrome P450 system Drug safety and toxicology (including drug-drug interactions) And much more! Gain deep insights into GPCR drug candidates and learn the critical assays and techniques required to bring therapeutic molecules to life. đ¨ Only 25 spots available â register now! đĄ This is a great opportunity for both academia and industry professionals. Sessions will be live, and youâll also have 1:1 discussion time with the instructor. Full PDFs of the slides will be available! đ https://buff.ly/lVEcRUc #GPCR #DrugDevelopment #Pharmacokinetics #TherapeuticDrugs #OnlineCourse #DrGPCRUniversity #PharmaceuticalIndustry | Dr. GPCR Ecosystem
GPCR University: "Development of GPCR Ligands as Therapeutic Drugs." đ Dates: March 20 - April 10, 2025 Gain deep insights into GPCR drug candidates and learn the critical assays and techniques required to đ https://buff.ly/lVEcRUc #GPCR #DrugDevelopment #Pharmacokinetics #TherapeuticDrugs #OnlineCourse # GPCR Courses đ¨ Exciting Opportunity for Professionals in Drug Development! GPCR University: "Development of GPCR Ligands as Therapeutic Drugs." đ Dates: March 20 - April 10, 2025
- Did you know that GPR20, a potential therapeutic target to treat gastrointestinal stromal tumours, performs high constitutive activity when coupling with Gi? Check out this paper to see how molecular dynamics simulation can be used to explore its constitutive activation mechanism. Check out the latest GPCR news in the Ecosystem today! Youâll need to register but donât worry, itâs Free! âĄď¸https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/exploring-the-constitutive-activation-mechanism-of-the-class-a-orphan-gpr20 #gpcr #drgpcr | Dr. GPCR Ecosystem
Check out the latest GPCR news in the Ecosystem today! receptor-activation-and-signaling/exploring-the-constitutive-activation-mechanism-of-the-class-a-orphan-gpr20 #gpcr #drgpcr Published on February 13, 2025 Category GPCR Weekly News Did you know that GPR20, a potential Check out the latest GPCR news in the Ecosystem today! receptor-activation-and-signaling/exploring-the-constitutive-activation-mechanism-of-the-class-a-orphan-gpr20 #gpcr
- How do GRK-specific phosphorylation barcodes influence β-arrestin binding to GPCRs? New cryo-EM structures from Chen et al. (Nature, 2025) reveal that β-arrestin1 and β-arrestin2 form distinct complexes with ACKR3 depending on whether it's phosphorylated by GRK2 or GRK5, shaping arrestin conformation, complex stability, and engagement mode. Surprisingly, arrestinâs finger loop didnât dive into the receptor core. Instead, it latched onto the micelle surface, breaking canonical expectations. Also, β-arrestin2 lacks a membrane anchor, making it more dynamic â a potential clue to its functional specialization. These findings underscore how barcode location + arrestin isoform = unique signaling outcomes. open book Read the full study: Inside Out: Mapping GPCRs from Membrane Codes to Market Moves #GPCRs #Arrestin #ACKR3 #GRKs #CryoEM #StructuralBiology #SignalingBias #Phosphorylation #DrGPCR | Dr. GPCR Ecosystem
Home â Flash News â How do GRK-specific phosphorylation barcodes influence β-arrestin binding to GPCRs + arrestin isoform = unique signaling outcomes. open book Read the full study: Inside Out: Mapping GPCRs from Membrane Codes to Market Moves #GPCRs #Arrestin #ACKR3 #GRKs #CryoEM #StructuralBiology #SignalingBias barcodes influence β-arrestin binding to GPCRs? Read the full study: Inside Out: Mapping GPCRs from Membrane Codes to Market Moves #GPCRs #Arrestin #
- New strategic partnership alert! đ Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research. Get custom, fast, and functional ligands backed by real scientists solving real assay problems. 𧪠âWe donât just deliver compounds. We solve assay problems.â â Dr. Maria Majellaro, CSO, Celtarys Listen to Ep. 168 now and meet your new assay partner đ âłď¸ https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-168-with-dr.-maria-majellaro-from-celtarys   #GPCRdrugDiscovery #FluorescentLigands #DrGPCR #BiotechTools #AssayDevelopment | Dr. GPCR Ecosystem
đ Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research Celtarys Listen to Ep. 168 now and meet your new assay partner đ âłď¸ https://www.ecosystem.drgpcr.com/dr-gpcr-podcast GPCR Podcast New strategic partnership alert! đ Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research Celtarys Listen to Ep. 168 now and meet your new assay partner đ âłď¸ https://www.ecosystem.drgpcr.com/dr-gpcr-podcast
- â ď¸Registration Deadline today! This is your last chance to register for âThe Practical Assessment of Signaling Biasâ with Dr. Terry Kenakin. Learn theoretical background for the techniques and apply with hands-on exercises đŞ âłď¸Last chance!!! https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr GPCR Courses â ď¸ Registration Deadline today! https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr
- Did you know that GPR180 helps regulate lipid metabolism and may play a role in preventing obesity? recent study shows that overexpression of GPR180 in adipose tissue improves lipid metabolism and protects against HFD-induced obesity, while its knockout worsens lipid accumulation. This finding highlights GPR180 as a potential therapeutic target for metabolic disorders! Catch up on this exciting research in the Ecosystem today! đđ Youâll need to register, but donât worryâitâs free! âĄď¸https://www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/gpr180-reduces-adiposity-by-inhibiting-lipogenesis-and-fatty-acid-uptake-in-adipocytes #gpcr #drgpcr #metabolism #obesity | Dr. GPCR Ecosystem
âĄď¸https://www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/gpr180-reduces-adiposity-by-inhibiting-lipogenesis-and-fatty-acid-uptake-in-adipocytes #gpcr #drgpcr #metabolism #obesity Published on March 3, 2025 Category GPCR Weekly News Did you know âĄď¸ https:// www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/gpr180-reduces-adiposity-by-inhibiting-lipogenesis-and-fatty-acid-uptake-in-adipocytes #gpcr #drgpcr #metabolism #obesity Previous Next Recent Articles
- Started in medicinal chemistry. Got hooked on ligand design. Dr. Maria Majellaro didnât plan to run a biotech company. A thesis project, a mentorâs advice, and a leap during the pandemic changed everything. Now sheâs leading Celtarys, building custom fluorescent probes, and partnering with Dr. GPCR to support assay development worldwide. Meet Celtarys and learn more about its leading work on ligand-linker-fluorophore chemistry đ âłď¸ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-168-with-dr.-maria-majellaro-from-celtarys #GPCRcommunity #DrGPCR #FluorescentLigands #GPCRdrugDiscovery #ScientificLeadership #BiotechInnovation | Dr. GPCR Ecosystem
GPCR to support assay development worldwide. leading work on ligand-linker-fluorophore chemistry đ âłď¸ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast GPCR Podcast Started in medicinal chemistry. Got hooked on ligand design. Dr. GPCR to support assay development worldwide. leading work on ligand-linker-fluorophore chemistry đ âłď¸ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast
- Did you know? đ Researchers have developed reversibly photoswitchable allosteric modulators for Class A GPCRs! đ§ŹđĄ These innovative compounds, âPhoto-BQCisAâ and âPhoto-BQCtrAns,â offer subtype-selective precision by combining allosteric modulation with light control, paving the way for new therapeutic strategies targeting muscarinic receptors (M1-M5). đŹâ¨ Learn more about this breakthrough in the Ecosystem! | Dr. GPCR Ecosystem
đ Researchers have developed reversibly photoswitchable allosteric modulators for Class A GPCRs! Published on December 3, 2024 Category GPCR Weekly News Did you know? đ Researchers have developed reversibly photoswitchable allosteric modulators for Class A GPCRs! âĄď¸ buff.ly/4fgX4ZH #gpcr #drgpcr Previous Next Recent Articles
- Content and Conduct Policy | Dr. GPCR Ecosystem
GPCR Ecosystem and promote a positive online community. Content and Conduct Policy Dr. GPCR, Corp, LLC (âDr. GPCRâ) provides its Service to you through our websites referred to as Dr. GPCR, Ecosystem.DrGPCR.com, DrGPCR.com. Please note that Ecosystem.DrGPCR.com is specializes in GPCR and related subjects. GPCR conducts business Affiliate Policy Content and Conduct Policy Content Guidance Privacy Policy Terms
- Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep.166 of the Dr.GPCR Podcast,. The catch? Itâs all about understanding the system, not replacing it. From neuromas to novel modulators, this episode is full of breakthroughs that matter for patients. đ˛ Watch now: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Home â Flash News â Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep GPCR Podcast Ben Clements reveals a 10x improvement in efficacy using GPCR-targeted PAMs, in Ep.166 of
- Seeking to gain more knowledge on signaling bias? Weâve got the perfect opportunity for you đ Registrations open until February 14th â ď¸ Last spots available for âThe Practical Assessment of Signaling Biasâ with Dr. Terry Kenakin âłď¸Register today at https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr GPCR Courses Seeking to gain more knowledge on signaling bias? https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr
- Deepen your understanding of signaling bias with Dr. Terry Kenakin's guidance by registering for the latest workshop at Dr.GPCR University đ Register and get hands-on exercises as well as theoretical background for the techniques. âłď¸Spots are limitedâregister now! âŹď¸ âĄď¸https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr GPCR Courses Deepen your understanding of signaling bias with Dr. :// www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr
- Fresh, Fresh, GPCR News â Feb 17 - 23, 2025 | Dr. GPCR Ecosystem
. đ Develop New GPCR Skills Join Dr. Classified GPCR News Letâs dive into the Classified GPCR News from February 17th to 23rd, 2025 Industry Peptide-Based Therapeutics Summit - USA April 2 - 3, 2025 | New therapeutic modalities: Transforming receptor pharmacology June 22 - 26, 2025 | G Protein-coupled Receptor Kinases and Arrestins - USA December 16 - 18, 2025 |Pharmacology 2025 - UK July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology - Australia GPCR
- What do mission-driven teams and world-class science have in common? â Integrity â Systems that last â The right people In this episode, Joe & Chuck from Company Launch Partners share what it means to build something that endures. đ§ Catch the full episode: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup | Dr. GPCR Ecosystem
Germain #gpcr #DrGPCR #ScienceStartup Published on May 6, 2025 Category Dr. GPCR Podcast What do mission-driven teams and world-class science have in common? Germain #gpcr #DrGPCR #ScienceStartup Previous Next Recent Articles
- In case you havenât heard, our next Dr.GPCR University course is open for registrations đ Learn about "The Practical Assessment of Signaling Bias" with Dr. Terry Kenakin. đ Hands-on exercises included! âłď¸Only 25 spots available âĄď¸Enjoy a 25% discount with your Premium Membership https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr | Dr. GPCR Ecosystem
https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr #drgpcr Published on January 24, 2025 Category GPCR University In case you havenât heard, our next Dr.GPCR https://www.ecosystem.drgpcr.com/event-details-registration/the-practical-assessment-of-signaling-bias #gpcr
- Your GPCR Order Has Arrived! â Feb 10 - 16, 2025 | Dr. GPCR Ecosystem
< Back Your GPCR Order Has Arrived! Classified GPCR News Letâs dive into the Classified GPCR News from February 10th to 16th, 2025 Industry discovery Symposium & Workshop NEW April 2 - 3, 2025 | New therapeutic modalities: Transforming receptor pharmacology Summit June 22 - 26, 2025 | G Protein-coupled Receptor Kinases and Arrestins NEW December 16 - 18, 2025 |Pharmacology 2025 July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs Structural
- đ Science and finance aren't oppositesâtheyâre partners. In this Ep.165 of the Dr.GPCR Podcast, Joe St. Germain & Chuck DeWeese reveal what it really takes to build sustainable startups and nonprofits behind the scenes. Grant accounting, character-first hiring, mission-driven growthâitâs all here! đ§ Listen now: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup | Dr. GPCR Ecosystem
Germain #gpcr #DrGPCR #ScienceStartup Published on April 29, 2025 Category Dr. GPCR Podcast đ Science and finance aren't oppositesâtheyâre partners. Germain #gpcr #DrGPCR #ScienceStartup Previous Next Recent Articles
- âResearch is all about knowing when to walk and when to run.â âBen Clements In Ep. 166 of the Dr.GPCR Podcast, hear how a postdoc is reshaping the conversation on opioid use, imposter syndrome, and the power of collaborative science. Why early-career voices are critical in GPCR drug discovery âand how lab culture makes all the difference. đ§ Watch here: https://buff.ly/Kr3qKud #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Why early-career voices are critical in GPCR drug discovery âand how lab culture makes all the difference GPCR Podcast âResearch is all about knowing when to walk and when to run.â Why early-career voices are critical in GPCR drug discovery âand how lab culture makes all the difference
- "Solving financial puzzles feels just like solving scientific ones," says Joe St. Germain from Company Launch Partners. Behind every successful research organization, there is a rock-solid operations team. Donât miss this rare conversation bridging science, structure, and strategy with Chuck DeWeese & Joe St. Germain. âłď¸ Tune in now: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup | Dr. GPCR Ecosystem
Germain #gpcr #DrGPCR #ScienceStartup Published on May 1, 2025 Category Dr. GPCR Podcast "Solving financial puzzles feels just like solving scientific ones," says Joe St. Germain #gpcr #DrGPCR #ScienceStartup Previous Next Recent Articles
- Genetic Deletion of Atypical VGLUT3 Rescues Huntingtonâs Disease Phenotype and Neurodegeneration in zQ175 Mice
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des RĂŠcepteurs Ă Sept Domaines Transmembranaires du QuĂŠbec Great Lakes GPCR Retreat and Club des RĂŠcepteurs Ă Sept Domaines Transmembranaires du QuĂŠbec 22nd GPCR Retreat Sponsored by
- Dinner 1
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Dinner 1 Date & Time Thursday, November 2nd / 8:00 PM Previous Event Next Event Great Lakes GPCR Retreat and Club des RĂŠcepteurs Ă Sept Domaines Transmembranaires du QuĂŠbec Great Lakes GPCR Retreat and Club des RĂŠcepteurs Ă Sept Domaines Transmembranaires du QuĂŠbec 22nd GPCR Retreat Sponsored by
- Breakfast 2
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Breakfast 2 Date & Time Saturday, November 4th / 7:30 AM Previous Event Next Event Great Lakes GPCR Retreat and Club des RĂŠcepteurs Ă Sept Domaines Transmembranaires du QuĂŠbec Great Lakes GPCR Retreat and Club des RĂŠcepteurs Ă Sept Domaines Transmembranaires du QuĂŠbec 22nd GPCR Retreat Sponsored by
- Poster Session #2
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to Poster Session #2 Date & Time Friday, November 3rd / 5:00 PM Previous Event Next Event Great Lakes GPCR Retreat and Club des RĂŠcepteurs Ă Sept Domaines Transmembranaires du QuĂŠbec Great Lakes GPCR Retreat and Club des RĂŠcepteurs Ă Sept Domaines Transmembranaires du QuĂŠbec 22nd GPCR Retreat Sponsored by
- Coffee Break 4
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Coffee Break 4 Date & Time Friday, November 3rd / 3:00 PM Previous Event Next Event Great Lakes GPCR Retreat and Club des RĂŠcepteurs Ă Sept Domaines Transmembranaires du QuĂŠbec Great Lakes GPCR Retreat and Club des RĂŠcepteurs Ă Sept Domaines Transmembranaires du QuĂŠbec 22nd GPCR Retreat Sponsored by
