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- Dr. Khaled Abdelrahman, Victoria Rasmussen and Madelyn Moore | Dr. GPCR Ecosystem
She is currently working to understand the signaling and degradation of GPCRs in disease states to help It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Maria Waldhoer: Pharmacological Fingerprints and the Limits of Bias | Dr. GPCR Ecosystem
compound on one receptor can be described by ten to fifteen pharmacological parameters β internalization rates , recycling and degradation rates, G protein affinity for the ligand-receptor complex, and more β rather Maria Waldhoer, CSO of InterAx Biotech 02:19 β From zoology to GPCRs: fate, not choice 06:48 β Academia It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Jane Lamerdin and Gaurav Agrawal: Building GPCR Assays That Reflect Real Biology | Dr. GPCR Ecosystem
assays, supporting client drug discovery campaigns, method development, and qualification of assays for late-stage Bridging that gap takes months of hardening work. Failure is documented, not buried. It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Kathryn Livingston: Allosteric Opioid Modulators and Receptor Signaling Beyond the Membrane | Dr. GPCR Ecosystem
Rather than measuring endpoint states, she learned to watch receptors move, internalize, and continue Live-cell imaging makes the dynamic pharmacology of GPCRs visible Where equilibrium assays capture endpoint states Industry can screen tens of millions of compounds in the time it takes to write a grant. It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
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- Hacking GPCRs: Tools, Tech & Drug Discovery with Tom Sakmar & Ilana Kotliar | Dr. GPCR Ecosystem
Sakmar recounts how a fateful phone call from Bruce Merrifield decades ago inspired his lifelong focus I want to take it forward.β β Ilana Kotliar Dr. It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Content Guidelines | Dr. GPCR Ecosystem
After we are notified of a potential policy violation, we may review the content and take action, including , or documentary considerations or when there are other substantial benefits to the public from not taking any other intellectual property or proprietary right; contains unlawful material, including illegal hate Hate Speech Our products are platforms for free expression. We will remove such content and take appropriate action, which may include disabling accounts and reporting
- Content and Conduct Policy | Dr. GPCR Ecosystem
After we are notified of a potential policy violation, we may review the content and take action, including , or documentary considerations or when there are other substantial benefits to the public from not taking any other intellectual property or proprietary right; contains unlawful material, including illegal hate Hate Speech Our products are platforms for free expression. We will remove such content and take appropriate action, which may include disabling accounts and reporting
- Ross Cheloha: Nanobody-GPCR Conjugates and the Engineering of Receptor Selectivity | Dr. GPCR Ecosystem
using non-natural amino acids Receptor conformation selectivity: G-protein coupled versus uncoupled states selectivity changes the duration of the signal PTH receptor exists in G-protein coupled and uncoupled states The analogs that preferentially bind the uncoupled state produce markedly prolonged signaling responses It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Silvio Gutkind: When GPCRs Drive Cancer | Dr. GPCR Ecosystem
protein hotspot mutations, why the canonical GΞ±Q pathway fails in uveal melanoma, and how CXCR3 may gate GΞ±Q signaling through TRIO, Rho, YAP, and the druggable FAK node CXCR3 and the chemokine axis that gates It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Irfan Dhanidina, Dr. Kathleen Caron and Dr. Lauren Slosky | Dr. GPCR Ecosystem
on the web University of Minnesota Department Page Twitter LinkedIn Google Scholar PubMed Research Gate It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Dr. Arthur Christopoulos | Dr. GPCR Ecosystem
focused on Arthur's transition to become Dean and his decision to move from Australia to the United States Podcast Format, Team Culture, and Science Yamina and Arthur concluded their discussion and decided to take It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Dr. Arthur Christopoulos | Dr. GPCR Ecosystem
focused on Arthur's transition to become Dean and his decision to move from Australia to the United States Podcast Format, Team Culture, and Science Yamina and Arthur concluded their discussion and decided to take It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Dr. GPCR Board | Dr. GPCR Ecosystem
Prior to that, they obtained a Bachelor of Arts (B.A.) degree from California State University, Long It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Custom Molecules, Fluorescent Probes: When Chemists Think Like Biologists with Dr. Maria Majellaro from Celtarys | Dr. GPCR Ecosystem
To date, she has successfully led seven funded projects. It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Graciela PiΓ±eyro: Partial Agonism, Receptor Recycling, and the Limits of Bias | Dr. GPCR Ecosystem
bias was supposed to Ξ΄-opioid receptor recycling from the lysosome β and why the post-internalization fate In a funding environment that rewards the opposite, the advice is harder to take than it sounds β and It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Dr. Demet Araç | Dr. GPCR Ecosystem
interest in science led him to study biology, genetics, and molecular biophysics in Turkey and the United States It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- GPCRs and the Science Behind Pain and Recovery with Dr. Alex Serafini | Dr. GPCR Ecosystem
point, he had a job offer at Roivant (a biotech firm known for repurposing shelved compounds), but a late-stage It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Dr. Christel Menet | Dr. GPCR Ecosystem
Galapagos where I spent almost 11 years and became head of medicinal chemistry. 6 years ago I decided to take on a new challenge by taking the position of CSO at Confo Therapeutics . It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Masha Niv: Bitter Taste Receptors and the Drug Discovery Blind Spot | Dr. GPCR Ecosystem
intersects with drug development - a collision that, for most of pharmaceutical history, has occurred too late a drug development variable - machine learning prediction, formulation consequences, and the FDA's late It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Gunnar Schulte: Frizzled Receptors and the GPCR Identity Question | Dr. GPCR Ecosystem
Scientific Themes of the Conversation The GPCR identity question β what it takes to make the case, and determines whether a signal flows through disheveled or through a G protein depending on its conformational state It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Lin and Ball: GPCR Antibody Characterization and the Recombinant Shift | Dr. GPCR Ecosystem
Is More Honest Than "Validated" - and the Difference Matters The word "validated" implies a finished state But to verify them - to characterize them, to validate them - it actually takes more effort. It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Elva Zhao: G Protein Regulation and Biased Signaling at the GLP-1 Receptor | Dr. GPCR Ecosystem
redirected the next chapter 22:28 The decision to pursue a postdoc - following the question before you hate I don't hate science yet. So why not do a little bit more?" It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- You never know where your GPCR takes you with Dr. Brian Hudson | Dr. GPCR Ecosystem
<< Back to podcast list Strategic Partner(s) You never know where your GPCR takes you with Dr. It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Jennifer Pluznick: Olfactory Receptors in the Kidney and the Gut-Microbe Signal | Dr. GPCR Ecosystem
She received her undergraduate degree in biology from Truman State University and earned her Ph.D. in It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Dr. Nicola J. Smith | Dr. GPCR Ecosystem
Her career goal is to leverage this expertise to establish a research program that takes orphan GPCRs It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Dr. John Janetzko | Dr. GPCR Ecosystem
John shared his experiences, stating that he submitted approximately 35 to 40 applications and that the It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Beatriz Blanco-Redondo: Adhesion GPCR Discovery in Drosophila | Dr. GPCR Ecosystem
It is a small detail, but it marks something real about the state of adhesion GPCR biology in insects It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Murat Tunaboylu & Ben Holland | Dr. GPCR Ecosystem
GPCR About Ben Holland "Ben gained his masters in Engineering Science from Oxford, taking a specialisation It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
- Dr. John Streicher: Reorganizing Opioid Signaling Beyond the Receptor | Dr. GPCR Ecosystem
Isoform-selective chaperone inhibition as an alternative to receptor-level drug design The current state It takes <60 seconds and makes a big difference. β Review on Apple Podcasts β Rate on Spotify βοΈ Send
