Sakmar recounts how a fateful phone call from Bruce Merrifield decades ago inspired his lifelong focus If you’re working on GPCRs, this is your call to leverage these tools , ask new questions, and help unlock

This research has led to a first-author Cell article on the development of a new biosensor platform called

receptors is activated by small-molecule metabolites produced by gut microbes, a finding she still calls Sequence-based orthology calls are often ambiguous, and in the Pluznick lab's hands, putative orthologs Jennifer Pluznick on the web John Hopkins Pluznick Lab Pubmed Ted Talk Dr.

At the height of curiosity, a seemingly naïve idea at the dinner table led to a side project by which

I was part of a study that identified the receptors of a novel human gut microbe-derived metabolite called most ubiquitous class of plasma membrane receptors and serve as targets for more than one-third of all prescribed drugs currently used in the treatment of human diseases all over the world.

activate distinct signaling outputs, and functional selectivity was quietly hiding inside what had been called were generated using AI for readability. 00:00 Introduction 02:25 The closet studio and what's in the talk "At NIH, I decided that I wanted to go what you'd call the dark side, which I don't think it's the dark I gave a talk on October 12th at the 3rd ERNEST meeting about the Dr.GPCR Ecosystem .

He compares the biochemist's approach to smashing a television with a wrecking ball and trying to reassemble "If you ask a biochemist how does a television work, he would probably take a wrecking ball to it and then try to piece all the little parts back together."

GPCR’s mission is to bring together the GPCR community from all corners of the world to connect, exchange So far we have recorded and released over 156 episodes and hosted GPCR specialists from all over the Randy Hall, tributes toDr. Marc Caronwith over 30 guests includingDr. Kathleen Caron, Dr.

Diagnose the mess → where your growth stalls. 2.

Tell your story with context, clarity, and purpose. Bonus: mentioned in podcast intros/outros. Book a 30-minute Strategy Call with Yamina to explore whether your capabilities fit within the GPCR CRO

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This theory states that the post-translational modification of GHSR1a’ C-terminal tail is not a docking

Oct 2021 — Featured at ERNEST with Where All GPCRs Are Created Equal . 2022 Building Momentum Podcast Randy Hall , Emory University. GPCR Summit , featuring 34 live talks , 12 poster presentations , one pre-recorded session , and four GPCR Symposium , bringing together over 100 attendees and featuring 11 live talks Community Engagement Jun 2023 — Featured Talk Molecular Pharmacology GRC and GRS in Switzerland.

One of the core values of this international meeting is to promote interactions among all participants of all diversity backgrounds, particularly between trainees and principal investigators. For the Ottawa 2017 GPCR Retreat, of the ten talks from trainees 80% were from women and 60% from visible The fall colors of the leaves are spectacular, and the weekend of science is an intense and interactive We would like to thank all our Sponsors for their ongoing generous support of the meeting.

Raise it further and inverse agonism appears where a calcium assay would have called the compound a neutral GPCR membership gives you access to all upcoming live, interactive webinars. Free.

joined the mission after pivoting from a sales career into accounting, where he found his professional calling

Regulators have begun telling companies directly that assays need to reflect near-primary expression The guests frame their work as talking to peers who understand the same pains, not selling a catalog. I like to call myself a jack of all trades, maybe master of none, but enough to be dangerous. You will not be disappointed to talk science about GPCRs when you reach out to us, and we love to talk

Each year she delivers roughly a hundred talks at universities and research institutions on resumes, title Job titles in biotech are often creative and inconsistent — a medical science liaison might be called Safety at work is a concrete culture signal Would an employee feel comfortable telling a manager their "I can tell you in speaking with thousands of PhDs, not everyone is collaborative. GPCR podcast episode, we sat down to chat with Lauren Celano to talk about career options for Ph.D.’s

We will then have a short call and send you the our Instructor Intake Form — it’s how we build your profile Course details – title, format (short talk / mini-course / series), audience, main objectives, expected

Insel calls armchair science. That's what this is all about, really." — Dr. Paul Insel "Almost most biological systems are all about gas pedals and brakes.

Falling for Computational Chemistry The "second academic love" arrived during his master’s thesis, where “Let’s embrace the challenge to study all of them… they’re unique in how they bind ligands, how selective

Yamina suggested having round tables to discuss these topics.

He stresses the value of lab “optimists and cynics,” the importance of talking about negative results , using Southern blots to hunt for a non-existent AT1 subtype, and the MAS oncogene as a cautionary tale

are writing the first chapter, without antibodies, no prior literature, and no established toolkit to fall Upcoming GPCR conferences in Leipzig and Dusseldorf Selected Quotes "It's like there's nothing known at all But then to see all the possibilities that this offers - that was also great."

on rapidly proliferating cells, such as cancer cells, and suggested a therapeutic index for a drug called

Streicher calls himself an "informed outsider" on bias now, but his read is that the field needs deeper

Arey calls this one of the most important and least instinctive skills in pharmaceutical research - and "All the key discoveries I've made in my career were based initially on intuition.

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Could you introduce yourself and tell us about your research? Dr. I can actually read runic inscriptions, and I find it fascinating to interpret what these stones tell Bengtsson: I'll tell you a story I don't share very often. One summer he asked me: “What happens if you fall through the ice?” I said I didn't know. Yamina Berchiche: Could you talk about how β₂-adrenergic signaling relates to muscle growth? Dr.