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Episode Timeline Timestamps were generated using AI for readability. 00:00 Summit week welcome and episode And what surprised me even more was his lab was paying thousands of dollars for this legacy-looking software

What differs is how scaffold proteins localize the kinase into distinct submolecular circuits. Brian Blagg's KU-32 actually promotes neuronal survival in diabetic peripheral neuropathy and is now

What came as a pleasant surprise was how didactical and well-thought-out his course was—highly recommended Also super-valuable for those of us learning how to teach pharmacology GPCR researcher Dr.

Craig Malbon at SUNY Stony Brook studying the role of G-protein coupled receptors (GPCRs) and their regulators GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy. Summary Science Roles and Resilience Yamina and Mike had a conversation about their roles and experiences They also discussed the challenges of the two-body problem, where both partners need to find suitable Yamina proposed further exploration of dosage and length of treatment in a mouse model and suggested

signaling and regulation of GPCRs from the adrenergic, purinergic, glutamatergic, GABAergic, and adhesion sub-families

GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy. Summary Personal Backgrounds and GPCR Interest Yamina and Demet had a discussion about their personal Demet, who had studied various subjects including chemistry, physics, biology, and math, shared his interest project since 2013, screening about 20 adhesion GPCRs, with the Latrophilin 3 construct proving most successful

pharmacology data analyst and the founder of Pharmechanics LLC , a consultancy and data analysis company supporting

Strong education with a Doctor of Philosophy (Ph.D.) in biochemistry under the supervision of Michel

These successes enabled the US$400M sale of Heptares Therapeutics Ltd. to the Sosei Group Corporation

Daniel Kahne and Suzanne Walker studying the structure and function of the essential human enzyme, O-GlcNAc GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy. He then moved to Dan's lab where he met Suzanne and her project. Ultimately, John did join the lab after his girlfriend successfully matched at Stanford. Yamina suggested having round tables to discuss these topics.

She subsequently joined Professor Mark Connor's laboratory at Macquarie University in Australia.

identifying ligands for orphan GPCRs by developing a powerful new computational tool for identifying ‘surrogate

He has successfully built numerous global life science, leadership teams, & works closely with both clients

Since 2013, he has been elected Chair of the subcommittee for the Dopamine receptors of the International

Nyla Naim Nyla is a Senior Scientist on the Scientific Support Team at Addgene . Nyla supports biomedical research by connecting researchers with resources and promoting reproducible Since then I transitioned into a Scientific Support role to leverage my passion for helping people!

UNC-CH, where she was the first to discover the essential role of adrenomedullin peptide for embryonic survival

was trained as a biochemist and molecular biologist during my Ph.D (2005) in Spain and Belgium, and subsequently AI Summary In the podcast episode "Anything but GPCRs" featuring Dr.

I am particularly interested in spatial signaling bias or how GPCRs can redistribute to different subcellular GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy. Summary Podcast Recording and Science Backgrounds Yamina and Badr discussed recording their podcast with due to the support of a theater group and a good teacher. He also explained his strategy for finding a suitable postdoc lab, which involved reaching out to labs

His studies led to new concepts in the GPCR field, such as the activation of cell surface receptors by

Sudarshan Rajagopal, a former postdoctoral fellow of Dr. Robert J. Lefkowitz . GPCRs, specifically, the role of differential receptor phosphorylation (phosphorylation barcodes) and subcellular After finishing his MD/Ph.D., Dylan plans to complete his residency training in Internal Medicine and subsequently

Ecosystem, with the goal is to bring together GPCR scientists, biotech, and pharma leaders as well as suppliers

arrestins and post-translational modifications (PTMs), such as phosphorylation, ubiquitination, and SUMOylation reveal the spatial and temporal requirements for GPCR activation of signaling pathways related to cell survival

He then joined WL/PD, where his lab demonstrated the existence of two subtypes of the adenosine A2 receptor He supported the D1 PAM project in various roles from its inception in 2002 until selection of a clinical

in 1989 and then moved to the University of Cambridge (Dept. of Biochemistry) to work on bacterial sugar Subsequent work has focused on understanding the molecular basis of GPCR pharmacology through structure or mini-Go, and also by electron cryo-microscopy of receptors coupled to mini G protein bound to βγ subunits

development of powerful multiplex tools designed to map GPCR-RAMP interactions across the receptor superfamily She expanded the original Family B focus to encompass the entire GPCR superfamily , building a digital and Computational Frontiers “There is no science that ends at a national border.” – Tom Sakmar The success Ilana graduated Summa cum laude from Cornell University, where she studied Chemistry and Chemical Biology

(MFI): a reliable, self-sustaining computational chemistry service provider, developing its own software I am now combining my training as a chemist and as an entrepreneur to grow a sustainable service and

Katarzyna handles submissions in structural biology, biophysics and biochemistry, with a particular focus

his trajectory took a sharp turn after struggling with unresolved, chronic pain following repeated surgeries

Throughout the episode, Ian reflects on the value of a supportive lab culture , the need for better experimental The conversation wraps with a playful exchange about possible podcast titles, with Yamina suggesting

Supportive collaborative environments accelerate scientific progress. Joseph Kim: Sure. There’s evidence suggesting that it plays roles in feeding behavior and analgesia , somewhat similar Some studies also suggest that the galanin receptors may interact with the μ-opioid receptor. lab where people were supportive and willing to teach.