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The conversation moves across discoveries that shaped a generation of GPCR pharmacology: the GABA-B heterodimer work spans GPCR structural biology, membrane protein stabilization, allosteric modulation, and the pharmacology Biased agonism, target validation, and animal-to-human translation failure Orphan GPCRs and the missing pharmacology 15:29 Unexpected allosteric pockets and the next wave of GPCR drug design 18:47 Which GPCR families pharma GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

GPCR Drug Discovery Gain insider methods from the pioneers shaping biased signaling, assay design, and pharmacology—skills Terry Kenakin Terry's Corner Author of 'A Pharmacology Primer', the definitive GPCR reference used by Sam Hoare Pharmechanics GPCR signaling & biased agonism expert regularly consulted by top pharma companies Pioneer in quantitative pharmacology methods. Dr. Yamina Berchiche Dr. Also super-valuable for those of us learning how to teach pharmacology Anonymous Dr.

Antonella Di Pizio: Computational Pharmacology of Taste and Olfactory Receptors Chemosensory receptors Antonella Di Pizio — who leads the computational pharmacology group at the Leibniz Institute for Food food chemistry and receptor pharmacology. With only about five known agonists, TAAR5 sits in a pharmacological twilight. Computational pharmacology is not a downstream silo. Dr.

. << Back to podcast list Strategic Partner(s) GPCR Pharmacology, Career Twists & Serendipity with Sokhom Starting at DuPont, then BMS, Novartis, and eventually founding in vitro pharmacology departments, Sokhom Falling in Love with GPCRs GPCR pharmacology captured his scientific curiosity. He blends classical receptor pharmacology with biosensor technology, always adapting to new tools and in the pharmaceutical industry, where he works mainly on GPCRs as therapeutic targets.

Foord reflects on discovering RAMPs, deorphanizing GPCRs, and navigating industrial GPCR pharmacology Foord: Serendipity, RAMPs, And Industrial GPCR Pharmacology Scientific Abstract This conversation traces pharmaceutical organizations. and GlaxoSmithKline working on GPCR pharmacology and drug discovery. Key Insights from the Conversation RAMPs Reframed Peptide GPCR Pharmacology . Dr.

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Tore Bengtsson on β₂-adrenergic receptor signaling, muscle metabolism, and how GPCR pharmacology can A central theme of the discussion is the pharmacology of the β₂-adrenergic receptor , a GPCR traditionally He is also an entrepreneur and founder of biotechnology companies translating GPCR pharmacology into This pharmacological limitation prevents their long-term use for metabolic therapies. That is exactly what makes GPCR pharmacology so fascinating and powerful.

Sam Hoare | Pharmechanics How Signaling Kinetics Shapes GPCR Drug Action Translational Pharmacology & Marsha Pierce | Midewestern University Introduction to GLP-1 pharmacology October 8, 2026 Dr. Also super-valuable for those of us learning how to teach pharmacology GPCR researcher Dr. The classes are designed for researchers, students, and professionals in biology, pharmacology, and biochemistry Masterclasses cover a variety of track including but not limited to pharmacology foundations, agonists

depth to satisfy the hunger for theory while being full of practical knowledge GPCR researcher The best pharmacology Also super-valuable for those of us learning how to teach pharmacology GPCR researcher Dr.

Explore upcoming GPCR Masterclass live sessions featuring expert discussions on GPCR pharmacology, receptor Sam Hoare | Pharmechanics How Signaling Kinetics Shapes GPCR Drug Action Translational Pharmacology & Focused audience of specialists Sessions bring together GPCR researchers, pharmacologists, and discovery Also super-valuable for those of us learning how to teach pharmacology GPCR researcher Dr. in academia, biotech, and pharmaceutical research.

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

A pharmacologist by training, she spent more than six years in early R&D at Novo Nordisk before turning Using the terms interchangeably blurs what each approach can realistically deliver in a pharmacology Most pharmacology datasets aren't useless for ML; they're incomplete. The explosion of biomedical data such as in genomics, structural biology, and pharmacology can provide GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

Her career has moved through academic pharmacology, a research fellowship in B-cell molecular immunology — why ~250 non-olfactory receptors remain outside clinical attention Career architecture for bench pharmacologists GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

Designed for structural pharmacologists, cell biologists, and drug discovery scientists working on GPCR

Delta Opioid Receptor and the Migraine Paradox Chronic migraine sits at a peculiar crossroads in opioid pharmacology She trained in pharmacology at McGill University with Paul Clarke and completed postdoctoral work at Her research integrates behavioral pharmacology, ligand-directed signaling, and mouse models of migraine , and has become central to the small community of basic pharmacologists working inside the headache For a pharmacologist, the resolution problem sits upstream of every other question.

Silvio Gutkind is Professor of Pharmacology and Associate Director of Basic Science at the UC San Diego His lab combines classical pharmacology with cancer genomics, bioinformatics, and synthetic lethality axis that gates immunotherapy response Structural biology, machine learning, and team science in GPCR pharmacology GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

receptor across 25 ligands, why δ-opioid receptors recycle from the lysosome, and the quantitative pharmacology Graciela Piñeyro — who leads an opioid receptor pharmacology group at the CHU Sainte-Justine Research Piñeyro, a physician-turned-pharmacologist whose early project in Michel Bouvier's lab felt like "torture as rescue operation — using operational models and BRET-based biosensors to pull pharmacological signal A quantitative model can turn an artifact into pharmacology. Early in her postdoc, Dr.

Paul Insel: Rethinking COVID-19 Pathobiology Through GPCR Signaling In the spring and summer of 2020, pharmacologist The review was accepted at Clinical Pharmacology and Therapeutics within weeks. Biology runs on opposing forces, and good pharmacology learns to see them. It is exactly the kind of work a pharmacologist does when the lab is closed. , British Journal of Pharmacology, and American Journal of Physiology-Cell Physiology.

the practical mechanics of holding a GPCR signaling lab together remotely; the continuity of receptor pharmacology of drug discovery logic and public health ethics, and illustrates how GPCR scientists reason about pharmacology Hebert's core pharmacology argument is that proposing a challenge trial — where volunteers receive placebo Terry Hébert is a Professor within the Department of Pharmacology & Therapeutics at McGill University GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

Graciela Pineyro is a professor of pharmacology at the department of pharmacology and physiology of the She has done extensive work on the molecular pharmacology of opioid receptors and is currently focusing on the pharmacology of cannabinoids in the context of pain. GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

Listeners will get a concrete look at what it means to modulate opioid pharmacology downstream of the John Streicher is an assistant professor in the Department of Pharmacology at the University of Arizona His lab combines cell and molecular biology with animal pharmacology to identify new signaling regulators A trained pharmacologist's first instinct is that the side effect burden would be crushing. John Streicher from the department of pharmacology at the University of Arizona.

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

< Back Introduction to GLP-1 pharmacology October 8, 2026 10 AM - 11:30 AM EST 🔒 Watch Recordings -

Designed for pharmacologists, drug discovery scientists, and translational researchers working on temporal postdoctoral training on Class B GPCRs at the National Institute of Mental Health, he spent 15 years as a pharmacology Sam is an editor at the NIH Assay Guidance Manual and regularly teaches advanced pharmacology and experimental

Work in his independent laboratory is focused on developing new pharmacological tools via chemistry and GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

Her work involves the pharmacological and structural characterisation of novel putative antipsychotic GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

Michael Feigin is an Associate Professor in the Department of Pharmacology and Therapeutics, and Director GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses