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GPCR Drug Discovery Gain insider methods from the pioneers shaping biased signaling, assay design, and pharmacology—skills Terry Kenakin Terry's Corner Author of 'A Pharmacology Primer', the definitive GPCR reference used by Sam Hoare Pharmechanics GPCR signaling & biased agonism expert regularly consulted by top pharma companies Pioneer in quantitative pharmacology methods. Dr. Yamina Berchiche Dr. Also super-valuable for those of us learning how to teach pharmacology Anonymous Dr.

Advance your GPCR research with expert-led Masterclasses on pharmacology, efficacy, signaling, and drug Also super-valuable for those of us learning how to teach pharmacology GPCR researcher Dr. The Masterclass is designed for GPCR researchers, pharmacologists, and drug discovery scientists working in academia, biotech, and pharmaceutical research. The format allows deeper exploration of pharmacology concepts than typical conference presentations.

How GPCR genetic variants shape psychiatric drug response - Hauser on pharmacogenomics, the iPSYCH biobank His research integrates GPCR molecular pharmacology, computational biology, and pharmacoepidemiology The approach treats the evolutionary record as a pharmacological hypothesis generator. 3. This is the argument for keeping computational pharmacologists embedded in pharmacological communities He received the “HC Ørsted Research talent prize” and “Bayer Pharmaceuticals Ph.D.

Bouvier on BRET, pharmacological chaperones, biased agonism, and why unexpected data is where real GPCR podcast list Strategic Partner(s) Michel Bouvier: BRET, Biased Agonism, and the Tools That Changed GPCR Pharmacology It describes the actual origin of BRET, pharmacological chaperones, and the inverse agonism work - each and chemists, the pharmacologists wanted to call it heresy. Since 2001, he holds the Canada Research Chair in Signal Transduction and Molecular Pharmacology.

GPCR biology, GPCRDB, biased signaling, and how the data analysis bottleneck is reshaping receptor pharmacology list Strategic Partner(s) David Gloriam: Orphan Receptors, GPCRDB, and the Data Revolution in GPCR Pharmacology GPCRs represent the largest and most pharmacologically important family of membrane receptors, yet a This conversation explores the intersection of computational biology, cheminformatics, and structural pharmacology The Bottleneck Has Flipped For most of the history of pharmacological research, generating reliable data

. << Back to podcast list Strategic Partner(s) GPCR Pharmacology, Career Twists & Serendipity with Sokhom Starting at DuPont, then BMS, Novartis, and eventually founding in vitro pharmacology departments, Sokhom Falling in Love with GPCRs GPCR pharmacology captured his scientific curiosity. He blends classical receptor pharmacology with biosensor technology, always adapting to new tools and in the pharmaceutical industry, where he works mainly on GPCRs as therapeutic targets.

why native cell systems change GPCR screening, constitutive beta-arrestin activity at FFA2, and the pharmacogenomics to podcast list Strategic Partner(s) Annette Gilchrist: Native Cell Systems, Biased Agonism, and the Pharmacogenomics How much bias is enough is not a pharmacological question with a single answer. by Hauser mapped pharmacogenomic variation across the GPCR-ome and showed, among other findings, that Gilchrist is also an associate professor at the Department of Pharmaceutical Sciences.

Pfleger on NanoBRET live-cell assays, receptor complex pharmacology, and what it took to move GPCR biology podcast list Strategic Partner(s) Pfleger: NanoBRET, Receptor Complexes, and the Translation of GPCR Pharmacology GPCR pharmacology has long depended on recombinant systems in which receptors are expressed and studied Those platforms have been applied across arrestin biology, receptor complex pharmacology, and the angiotensin Pfleger trained as a pharmacologist and obtained his Ph.D. at the University of Edinburgh.

Foord reflects on discovering RAMPs, deorphanizing GPCRs, and navigating industrial GPCR pharmacology evolved inside one of the world’s largest pharmaceutical organizations. and GlaxoSmithKline working on GPCR pharmacology and drug discovery. Key Insights from the Conversation RAMPs Reframed Peptide GPCR Pharmacology . Dr. Reflecting on his path from physiology to molecular pharmacology to bioinformatics, Dr.

Eleonora Comeo synthesizes fluorescent ligands to watch adenosine receptor pharmacology happen in living keeps failing. << Back to podcast list Strategic Partner(s) Eleonora Comeo: Fluorescent Ligands and the Pharmacology Eleonora Comeo, PhD candidate at the University of Nottingham and the Monash Institute of Pharmaceutical produces molecules that make receptor behavior visible Adenosine receptor subtype pharmacology - the Visibility changes what pharmacology can ask Fluorescent ligands do more than confirm receptor binding

. << Back to podcast list Strategic Partner(s) Antonella Di Pizio: Computational Pharmacology of Taste Antonella Di Pizio — who leads the computational pharmacology group at the Leibniz Institute for Food food chemistry and receptor pharmacology. With only about five known agonists, TAAR5 sits in a pharmacological twilight. Computational pharmacology is not a downstream silo. Dr.

Sam @Pharmamechanic Listen and subscribe where you get your podcasts

Advanced GPCR webinars for pharmacologists and biotech scientists. Live Q&A. Deep-dive sessions focused on real pharmacology, real drug discovery challenges, and real translational Terry Kenakin - UNC Chappel Hill | Terry's Pharmacology Corner Topics Covered The biological basis of GPCR pharmacology, signaling, structural biology, allosteric modulation, biased agonism, assay design Do I need prior knowledge of GPCR pharmacology?

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

Marsha Pierce | Midewestern University Introduction to GLP-1 pharmacology Coming Soon What makes this Focused audience of specialists Sessions bring together GPCR researchers, pharmacologists, and discovery Also super-valuable for those of us learning how to teach pharmacology GPCR researcher Dr. in academia, biotech, and pharmaceutical research. The format allows deeper exploration of pharmacology concepts than typical conference presentations.

Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

mainly focused on screening and assay development to bridge the gap between in vitro and in vivo GPCR pharmacology GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

CONVERSATION The receptor hypothesis before proof — The conceptual and experimental gap between classical pharmacology's Beta-adrenergic receptors as a model system — Why the adrenergic system, with its rich pharmacological Lefkowitz committed to receptor research in the early 1970s, prominent pharmacologists, including Raymond proximate, measurable downstream signal), cardiovascular relevance (matching his clinical training), and a pharmacological GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

Maudsley Stuart graduated from the University of Leeds in the U.K. with a First Class Honors degree in Pharmacology To broaden his biomedical skill-set Stuart next accepted the position of Head of the Receptor Pharmacology GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

receptor across 25 ligands, why δ-opioid receptors recycle from the lysosome, and the quantitative pharmacology Graciela Piñeyro — who leads an opioid receptor pharmacology group at the CHU Sainte-Justine Research Piñeyro, a physician-turned-pharmacologist whose early project in Michel Bouvier's lab felt like "torture as rescue operation — using operational models and BRET-based biosensors to pull pharmacological signal A quantitative model can turn an artifact into pharmacology. Early in her postdoc, Dr.

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

Any CRO focused on GPCRs, pharmacology, discovery biology, or antibody discovery—regardless of size or Let’s talk about how I support GPCR discovery, pharmacology strategy, and cross-functional execution

Get Team Access Terry's Pharmacology Corner Team Membership The team tier of Terry's Corner. Kenakin's weekly insights and AMAs — building shared language around GPCR data and pharmacological decisions University Expert-led courses spanning GPCR drug discovery — from receptor biology to translational pharmacology Explore the University Terry's Pharmacology Corner Weekly expert content and live AMAs led by Dr. Translates complex GPCR pharmacology into practical understanding you can apply to data interpretation

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

Gaetan Guillemette in the Pharmacology department at the Université de Sherbrooke. The pharmacology of latrophilins brings about a great deal of challenges given that they are highly polymorphic GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

I then started my career at Evotec before moving to Domain Therapeutics (called Faust pharmaceutical GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses

GPCR Learning Ecosystem ✔ Full Masterclass library ✔ Terry's Pharmacology Corner ✔ Advanced GPCR courses