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- Newsletter for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
, Mexico City, Mexico October 23-25 Register AGPCR Newsletter Adhesion GPCR Consortium Newsletter - May
- "Solving financial puzzles feels just like solving scientific ones," says Joe St. Germain from Company Launch Partners. Behind every successful research organization, there is a rock-solid operations team. Don’t miss this rare conversation bridging science, structure, and strategy with Chuck DeWeese & Joe St. Germain. ✳️ Tune in now: Ep 165 with Chuck DeWeese & Joe St. Germain #gpcr #DrGPCR #ScienceStartup | Dr. GPCR Ecosystem
Germain #gpcr #DrGPCR #ScienceStartup Published on May 1, 2025 Category Dr.
- A high-resolution deep mutational scan of MC4R reveals how thousands of genetic variants impact obesity-linked signaling pathways and highlights new opportunities for precision drug discovery Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr#drgpcr | Dr. GPCR Ecosystem
high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr#drgpcr Published on May
- Disrupting VIPR2 dimerisation halts breast cancer spread—could TM3-4 peptides be the next breakthrough in targeted cancer therapy? Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️ https://www.ecosystem.drgpcr.com/gpcrs-in-oncology-and-immunology/dimerisation-of-the-vip-receptor-vipr2-is-essential-to-its-binding-vip-and-g%CE%B1i-proteins%2C-and-to-its-functions-in-breast-cancer-cells #gpcr#drgpcr | Dr. GPCR Ecosystem
is-essential-to-its-binding-vip-and-g%CE%B1i-proteins%2C-and-to-its-functions-in-breast-cancer-cells #gpcr#drgpcr Published on May
- Can we preserve opioid pain relief without the side effects? 🔬 On Ep.166 of the Dr.GPCR Podcast, Ben Clements shares how positive allosteric modulators (PAMs) at the mu-opioid receptor could revolutionize treatment —with a 10x boost in methadone efficacy. Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship. 🎧 Full episode: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery Published on May 15
- Dr. GPCR Affiliate Program | Earn by Empowering the GPCR Community
GPCR may also remove affiliates from the program at any time. Yes, you may join the affiliate program as long as you have a verified PayPal account. Please note that we may withhold awards where we believe customers are acting in bad faith or otherwise
- Dr. GPCR Summit 2021 | Dr. GPCR Ecosystem
Cons: It may take more time to record an excellent presentation, but nothing is impossible! Pros: It may take less time to prepare for the presentation Cons: You may make mistakes since it's a
- What if you could map GPCR-RAMP interactions across the entire superfamily in a single experiment? That’s precisely what Dr. Kotliar from the Sakmar lab made possible! In Ep.167 of the Dr. GPCR Podcast, we chat with Drs. Tom Sakmar and Ilana Kotliar about how their lab developed: A multiplexed Luminex assay to screen hundreds of interactions at once A 220-clone DUET-tagged GPCR library, available on Addgene An online interface to search GPCR-RAMP data and antibody validations This is open-access science at its best, built for the GPCR research community. ✳️ Listen to the episode: Ep 167 with Drs. Tom Sakmar & Ilana Kotliar #GPCRresearch #DrGPCRecosystem #GPCRdrugdiscovery #GPCRtrainingprogram #GPCRpodcast | Dr. GPCR Ecosystem
Kotliar #GPCRresearch #DrGPCRecosystem #GPCRdrugdiscovery #GPCRtrainingprogram #GPCRpodcast Published on May
- Did you know that certain ergot derivatives can produce wash-resistant signalling through the 5-HT2B receptor persisting for many hours without losing potency or efficacy? By using signalling assays, radioligand binding assay, and microscopy, Gaidarov et al. suggested that this phenomenon results from persistently/irreversibly internalised signalling receptor complexes. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️ https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/mechanisms-of-constitutive-and-agonist-induced-5-ht2b-internalization%2C-persistent-endosomal-signaling-and-paradoxical-regulation-of-agonist-pharmacology #gpcr#drgpcr | Dr. GPCR Ecosystem
2C-persistent-endosomal-signaling-and-paradoxical-regulation-of-agonist-pharmacology #gpcr#drgpcr Published on May
- Session I | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
At low force or no force conditions, aGPCR may be reversibly regulated by binding and dissociation of and prevents the receptor from going back to its inactive resting state, the ECR-mediated mechanism may The ECR-mediated mechanism may also enable responding to compressing forces on the receptor, that directly In cases where a large “pulling” force is executed on the ECR, the ECR may be removed from the 7TM releasing
- Travel Tips for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Mexico travel advice *Travelers are encouraged to consult their country's embassy advisories as they may suggest reserving accommodations in the city's center as the housing around the venue is scarce, and some may
- Dr. Yamina Berchiche | Dr. GPCR Ecosystem
would like to discuss the opportunities, weaknesses, and advantages of these new technologies, which may
- Legal Policies and Disclaimers | Dr. GPCR Ecosystem
do not have such authority, or if you do not agree with this ATS, you must not accept this ATS and may
- Exploring Career Paths in GPCR Research with Dr. Jacek Mokrosiński | Dr. GPCR Ecosystem
His research aimed at understanding molecular mechanism through which rare genetic variation may lead GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy.
- Visualizing GLP-1 & GIP Receptors in Islets and Brain | Dr. GPCR Ecosystem
imaging evidence clarified unexpected glucagon-derived peptide behavior How future metabolic therapies may
- Dr. Gregory Tall | Dr. GPCR Ecosystem
Our current goals are to explore this mechanism in detail and to understand how it may happen for the
- Dr. Michel Bouvier | Dr. GPCR Ecosystem
As some of you may know, Michel was one of my professors at the Universite de Montreal.
- How do GPCRs sense pH changes? New cryo-EM structures of GPR4 and GPR68 reveal how extracellular histidines act as proton sensors-trigger activation and biased G protein coupling! Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! ➡️https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/structural-basis-and-biased-signaling-of-proton-sensation-by-gpcrs-mediated-by-extracellular-histidine-rearrangement #gpcr#drgpcr | Dr. GPCR Ecosystem
structural-basis-and-biased-signaling-of-proton-sensation-by-gpcrs-mediated-by-extracellular-histidine-rearrangement #gpcr#drgpcr Published on May
- Session VII | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Remo may serve a role in this peculiar signaling pathway and require further analysis."
- Fresh, Fresh, GPCR News ❇ Feb 17 - 23, 2025 | Dr. GPCR Ecosystem
2025 | American Physiology Summit 2025 - USA April 25 - 30, 2025 | AACR Annual Meeting 2025 - USA NEW May 1 - 2, 2025 | 5th Ace Drug Discovery Summit 2025 - USA NEW May 12 - 15, 2025 | ACSMEDI-EFMC Medicinal Chemistry Frontiers 2025 - USA May 12 - 15, 2025 | PEGS 2025 - USA May 15 - 17, 2025 | 23rd GPCR Retreat 2025 - USA May 20 - 22, 2025 | SLAS Europe 2025 - Germany May 20 - 22, 2025 |4th GPCRs-Targeted Drug
- Dr. Claudia Stäubert | Dr. GPCR Ecosystem
GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy.
- Your GPCR Order Has Arrived! ❇ Feb 10 - 16, 2025 | Dr. GPCR Ecosystem
✅ Practical Quantification of Allosteric Modulation – May 1, 2025 ✅ Applying the Black/Leff Operational April 24 - 27, 2025 | American Physiology Summit 2025 April 25 - 30, 2025 | AACR Annual Meeting 2025 May 12 - 15, 2025 | PEGS 2025 May 15 - 17, 2025 | 23rd GPCR Retreat 2025 May 20 - 22, 2025 | SLAS Europe 2025 NEW May 20 - 22, 2025 |4th GPCRs-Targeted Drug Discovery Summit June 22 - 26, 2025 | G Protein-coupled
- U - Landing Page | Dr. GPCR Ecosystem
Some classes may require basic knowledge of GPCRs, but many are designed to accommodate beginners as
- Dr. Demet Araç | Dr. GPCR Ecosystem
GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy.
- GPCR Courses
Some classes may require basic knowledge of GPCRs, but many are designed to accommodate beginners as
- When to Walk, When to Run: Lessons from the GPCR Trenches with Dr. Ben Clements | Dr. GPCR Ecosystem
scaffolds like thiazolidines and xanthinediones, Ben is helping define how structurally different PAMs may
- Dr. Aurélien Rizk | Dr. GPCR Ecosystem
GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy.
- Self-Learning, Collaboration, and Delegation in Science with Dr. Badr Sokrat | Dr. GPCR Ecosystem
GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy. Yamina will balance her scientific work with personal interests and activities to maintain a healthy , face, such as imposter syndrome, constant pressure from administrative tasks, and difficulties in maintaining They also highlighted the benefits of maintaining a supportive network and engaging in non-lab activities
- Dr. Arthur Christopoulos | Dr. GPCR Ecosystem
GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy. explored the idea of starting a similar talk show format to 'Between Two Ferns', the importance of maintaining disruption within the pharmaceutical sector, the importance of workforce development, and the need for maintaining
- Dr. Arthur Christopoulos | Dr. GPCR Ecosystem
GPCR AI Summary AI-generated content may be inaccurate or misleading. Always check for accuracy. explored the idea of starting a similar talk show format to 'Between Two Ferns', the importance of maintaining disruption within the pharmaceutical sector, the importance of workforce development, and the need for maintaining
