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Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Session IV AGPCRs signaling

Stony Brook studying the role of G-protein coupled receptors (GPCRs) and their regulators in the Wnt signaling vitro to in vivo work, and Mike explained that he wanted to use better models to understand cancer signaling

Some of these studies resolved a major question regarding the signaling differences in G protein splice

We focus on several aspects of metabolite-sensing GPCRs including signal transduction, intracellular

He discusses biased signaling in GPCR research, developing biosensors for G protein activity, networking Highlights of the week Structural insights into prolactin-releasing peptide receptor signaling and G-protein drug discovery: Cell-based assays for GLP-1 and the G-Suite - Online March 17 - 21, 2025 | 2nd GPCR signaling and G-protein coupling selectivity Decoding the structural basis of ligand recognition and biased signaling in the motilin receptor 🔎 GPCR KEYWORDS GPCR , structural biology , biased signaling , metabolism ,

vitro technologies to study mechanistic properties of GPCRs and understanding the dynamics of receptor signalling

For targets such as CB2, where nuanced shifts in receptor conformation affect signaling outcomes, a whole-cell

Master the classic players in GPCR pharmacology and learn how agonists and antagonists shape efficacy, signaling

improved their understanding of the GPCRs through various approaches, including structural biology and signaling

Stay at the Forefront of GPCR Drug Discovery Gain insider methods from the pioneers shaping biased signaling Sam Hoare Pharmechanics GPCR signaling & biased agonism expert regularly consulted by top pharma companies

Kotliar built a multiplexed platform to map GPCR-RAMP interactions and uncover autoantibody-driven GPCR signaling

They also delved into the different signaling of Class B receptors and the potential for modulation at

The Practical Assessment of Signaling Bias Dr. Terry Kenakin < Back Workshop Summary Join Dr. Terry Kenakin , a leading expert in pharmacology, as he unpacks the fascinating world of signaling bias how different ligands (compounds) can stabilize unique receptor conformations, leading to distinct signaling Key Highlights 🔍 Bias is Everywhere : Signaling bias naturally occurs in pharmacology—whether we look This allows for a side-by-side comparison of how different compounds influence receptor signaling. 📌