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150 items found for "Confo Therapeutics"

  • GPCR signaling contributes to immune characteristics of microenvironment and process of EBV-induced lymphomagenesis

    Therapeutic targeting CCR1 showed promising efficacy with EBV eradication, T-cell activation, and lymphoma GPCR-mediated malignant progression and translated sensors of viral molecules into EBV-specific anti-cancer therapeutics

  • 21-08 Dr GPCR Newsletter

    We want to thank our partner Domain Therapeutics for their support and for helping us bring you this Domain Therapeutics is a biopharmaceutical company committed to discovering and developing innovative Twist Biopharma provides end-to-end Solutions in Biologics Discovery & Early Development/ GPCR Therapeutics GPCR Therapeutics's mission is to discover and develop innovative therapeutics targeting cancer based the protein-lipid interface: strategic considerations for drug design G-protein-coupled receptors as therapeutic

  • Ep 05 with Dr. Terry Hébert

    Terry Hébert is a Professor within the Department of Pharmacology & Therapeutics at McGill University

  • Ep 83 with Dr. Jean-Philippe Pin

    biosensors, cryo-EM, photoswitchable ligands, and nanobodies as pharmacological tools and potential therapeutic

  • 21-10 Dr GPCR Newsletter

    We'd also like to express our gratitude to our partners for their support: Domain Therapeutics , a biopharmaceutical GPCR Therapeutics with the mission is to discover and develop innovative therapeutics targeting cancer pathway in the spinal cord contributes to morphine-induced hyperalgesia and tolerance Smoothened is a therapeutic Option The CXCL12/CXCR4/ACKR3 Axis in the Tumor Microenvironment: Signaling, Crosstalk, and Therapeutic Keystone Symposia in-person meeting- GPCRs: An Odyssey from Structure, Signaling, and Regulation to Therapeutics

  • 23-05 Dr GPCR Newsletter

    Ecosystem Partners We are grateful to Domain Therapeutics , GPCR Therapeutics , Design Pharmaceuticals

  • Single cell G-protein coupled receptor profiling of Transcription factor 21 expressing activated kidney fibroblasts

    matrix in chronic kidney disease (CKD) and G-protein coupled receptors (GPCRs) are the most druggable therapeutic Study of GPCRs expressed by these cells may identify new opportunities for CKD therapeutics. " Authors

  • Ep 82 with Dr. Lauren M. Slosky

    protein-coupled receptors (GPCRs) regulate motivated behavior and how these receptors can be targeted for therapeutic distinct signaling pathways with their physiological effects and may serve as the basis for more selective therapeutics

  • Ep 82 with Dr. Lauren M. Slosky

    protein-coupled receptors (GPCRs) regulate motivated behavior and how these receptors can be targeted for therapeutic distinct signaling pathways with their physiological effects and may serve as the basis for more selective therapeutics

  • Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy

    As therapeutic options are limited, novel targets, and agents for therapeutic intervention are urgently

  • 20-07 Dr GPCR Newsletter

    The endosomal signaling of delta-opioid receptors is an endogenous mechanism and therapeutic target for Thibaut Brugat, a project leader at Domain Therapeutics spoke at BIOTechnoGE's Round table discussion develop the next generation of allosteric modulators as therapies against rare diseases called Find Therapeutics Karuna Therapeutics Announces Positive Outcome of End-of-Phase 2 Meeting with the FDA for KarXT for the Domain Therapeutics presented 4 posters on the last developments of its oncology/Immuno-oncology franchise

  • 22-05 Dr GPCR Newsletter

    A correlation study of adhesion G protein-coupled receptors as potential therapeutic targets in Uterine inflammation. 1.8 Reviews Oxytocin and vasopressin: Signalling, behavioural modulation and potential therapeutic Comprehensive insights in GRK4 and hypertension: From mechanisms to potential therapeutics. 2. Glenn Vraniak as Chief Financial Officer Domain Therapeutics Raises $42m Series A Financing Sosei Heptares Duchamp has been selected as a 30 under 30 Europe Forbes ranking 2022 for science and healthcare GPCR Therapeutics

  • 23-04 Dr GPCR Newsletter

    Ecosystem Partners We are grateful to Domain Therapeutics , GPCR Therapeutics , Design Pharmaceuticals

  • 23-06 Dr GPCR Newsletter

    Ecosystem Partners We thank Domain Therapeutics , GPCR Therapeutics , Design Pharmaceuticals , Montana

  • 21-03 Dr GPCR Newsletter

    contribution to signal transduction in living cells 1.7 GPCR Opinion Pieces Can GPR4 Be a Potential Therapeutic signaling: Role in mediating the effects of early adversity in psychiatric disorders Mini-review: The therapeutic to companions Chemogenetic approaches to identify metabolically important GPCR signaling pathways: therapeutic Lymphocytes Regulatory roles of G-protein coupled receptors in adipose tissue metabolism and their therapeutic Meetings GPCR Colloquium May 10-11,2021 Psychedelic Therapeutics and Drug Development Conference May

  • 22-12 Dr GPCR Newsletter

    Ecosystem Partners We are grateful to Domain Therapeutics , GPCR Therapeutics , Design Pharmaceuticals GPCRs in Cardiology, Endocrinology, and Taste GRK2 in cardiovascular disease and its potential as a therapeutic 2-adrenergic receptor in oral squamous cell carcinoma: an emerging prognostic indicator and future therapeutic Comprehensive insights in GRK4 and hypertension: From mechanisms to potential therapeutics. GPCRs as an emerging host-directed therapeutic target against mycobacterial infection: From notion to

  • Ep 19 with Dr. Fiona Marshall

    As a co-founder of Heptares Therapeutics , now called Sosei Heptares , a GPCR-focused drug discovery

  • Ep 13 with Dr. Amynah Pradhan

    Andrew Charles that who specialized in animal models of migraine and delta-opioid receptors as a therapeutic

  • Ep 13 with Dr. Amynah Pradhan

    Andrew Charles that who specialized in animal models of migraine and delta-opioid receptors as a therapeutic

  • Ep 19 with Dr. Fiona Marshall

    As a co-founder of Heptares Therapeutics , now called Sosei Heptares , a GPCR-focused drug discovery

  • 23-01 Dr. GPCR Newsletter

    Ecosystem Partners We are grateful to Domain Therapeutics , GPCR Therapeutics , Design Pharmaceuticals

  • Ep 59 with Dr. Nicola J. Smith

    orphan GPCRs from ‘locked’, inaccessible receptors to well-characterized and understood ‘unlocked’ therapeutic

  • Ep 80 with Dr. Andrew Tobin

    vehicle by which Andrew is translating fundamental findings to commercial products is Keltic Pharma Therapeutics

  • Ep 34 with Dr. Brian Arey

    His recently published book on signaling bias, Biased Signaling in Physiology, Pharmacology, and Therapeutics

  • Ep 16 with Dr. Aaron Sato

    record as a biologics leader as he led teams to discover and develop novel first-in-class antibody therapeutics

  • Ep 35 with Dr. Brian Arey

    His recently published book on signaling bias, Biased Signaling in Physiology, Pharmacology, and Therapeutics

  • Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma

    of GPCRs in disease states to help test the feasibility of using protein-targeted degradation as a therapeutic

  • Ep 56 with Dr. Adriano Marchese

    The ultimate goal of Adriano’s research is to target novel aspects of GPCR signaling for therapeutic

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