Search Results

I was recently awarded a Marie Sklodowska Curie PostDoc Fellowship in order to investigate and find better

the nerve synapse might impact integrated behavior and what we might learn from these mechanisms to cure After doctoral training at the Pierre and Marie Curie University in Paris and a short internship at Genentech the CNRS as a Research Fellow in 1987 in the INSERM Laboratory directed by Jean-Charles Schwartz in Paris From 91 to 94, he was an assistant professor at Duke University in North Carolina, working with Marc Neurobiology of Psychiatric Disorders," first in Créteil with Marion Leboyer, then at the University of Paris-Sorbonne

Maria Waldhoer "I am a pharmacologist with a ~30 years background in academia and industry, working both Maria Waldhoer on the web LinkedIn T witter Pubmed Dr. GPCR About Dr. JoAnn Trejo "Dr. GPCR About Anne Marie Quinn "Anne Marie Quinn has a long and varied work experience in the biocomputing Anne Marie Quinn attended Yale University from 1998 to 2000, where they earned a Master of Public Health Anne Marie Quinn on the web Google Scholar The Org LinkedIn Twitter Dr.

Andrew Tobin Andrew Tobin studied Biochemistry at Queen Mary College, the University of London obtaining

<< Back to podcast list Strategic Partner(s) Chris Langmead Chris Langmead is Professor, Deputy Director the field of psychiatry, where he has led multiple projects into late stage preclinical development, many Prior to joining Heptares, Chris was a neuroscience researcher at GlaxoSmithKline, UK (1998-2009). Chris serves on the editorial boards of the British Journal of Pharmacology, ACS Chemical Neuroscience

." - Anne Marie Quinn, CEO Montana Molecular Frequently Asked Questions 01 What kinds of CROs do you

Chris Tate About this episode Dr. Chris Tate obtained his Ph.D. from the University of Bristol in 1989 and then moved to the University Chris also worked on the E. coli multidrug transporter EmrE and obtained both 2D and 3D crystals as well Join me to learn more about Chris’s work and his role in founding Heptares which was later acquired by Chris Tate on the web LinkedIn ResearchGate Pubmed Google Scholar Sosei Heptares Wikipedia MRC Laboratory

Kari Johnson About this episode Dr. Kari Johnson is currently an assistant professor at the Uniformed Services University of the Health Sciences Kari completed her Ph.D. in Pharmacology at Vanderbilt University before continuing her training as a Join me and learn more about how Kari studies GPCRs in basal ganglia circuits following chronic alcohol Kari Johnson on the web LinkedIn Google Scholar Research Gate USU Twitter Dr.

Anne Marie Quinn, CEO Montana Molecular As a CRO, we were delivering high-quality data across complex Bringing her in marked a meaningful shift.

Streicher on how HSP90 flips direction between brain and spinal cord, why isoform-selective inhibitors may plays directly opposite roles in the brain and the spinal cord, why isoform-selective HSP90 inhibitors may Mary Canals' group has argued that some of the apparent bias benefits may actually reflect low intrinsic

She began her Ph.D. at Imperial College London with Prof Aylin Hanyaloglu, Prof Gary Frost, and Dr.

Marshall walks through the decade when membrane proteins kept failing to crystallize in detergent, and how Chris Chris Tate's thermostabilization strategy, which introduced stabilizing mutations selected by thermal Marshall's caution is hard-won: many animal-model-validated GPCR drugs have failed in the clinic precisely Chris Tate and Dr. Richard Henderson at the Laboratory of Molecular Biology in Cambridge, UK.

California at Irvine, studying the regulation of ionotropic glutamate receptors under the direction of Gary

Maria Majellaro—and learn what their new partnership with Dr. curiosity to biotech force. Translating Science into Business Like many scientists-turned-entrepreneurs, Maria faced the challenge About Maria Majellaro Dr. at the University of Bari (Italy) in 2018.

Amynah Pradhan on why mu opioids worsen migraine, why delta agonists may relieve it, and how chronic Clarke and completed postdoctoral work at AstraZeneca, with Brigitte Kieffer in Strasbourg, and with Chris Delta agonists may finally have a disease. After failed trials in depression and pain, Dr. Her "bugaboo": we still do not know reliably where many GPCRs live — which cell type, which compartment Chris Evans at UCLA.

I’m really curious about your career trajectory. Dr. Joseph Kim: Sure. Some studies also suggest that the galanin receptors may interact with the μ-opioid receptor. In fact, some groups believe there may even be dimeric interactions between the receptors. Whenever I hear about peptide-binding GPCRs with buried or hydrophobic binding pockets, I immediately The endogenous peptide is buried laterally within the receptor, which means an exogenous small molecule

Joining the conversation are Maria Majellaro (CSO and co-founder of Celtarys Research), Johannes Broichhagen Broichhagen About the Guests Maria Majellaro, PhD Dr. Maria Majellaro is the Chief Scientific Officer and co-founder of Celtarys Research , a biotech spin-off She earned her PhD in medicinal chemistry from the University of Bari in 2018, including research training Guests on The Web Maria Majellaro LinkedIn ResearchGate Ecosystem Johannes Broichhagen LinkedIn Google

. << Back to podcast list Strategic Partner(s) From Curiosity to Breakthrough: Ajay Yekkirala on GPCR Ajay Yekkirala shares the pivotal moments that transformed him from a curious PhD student into a GPCR Ajay reveals how humility, curiosity, and collaboration fuel the future of drug discovery. translational innovation Biotech investors and strategic leaders seeking new drug development models Anyone curious His story is one of relentless curiosity, humility in the face of complexity, and an unshakable belief

Maria Majellaro Co-Funder and CSO Dr. Maria Majellaro earned her degree in Pharmaceutical Chemistry and Technology from the University of Bari validation strategy, and performance across reference antagonists and agonis Lucía from Celtarys Research Mar Maria Majellaro, CSO of Celtarys. “Working with Dr.

GPCR Podcast - The Voice of the Community Whether you’re a scientist, student, or just curious, you’ll

Jennifer Pluznick explains why olfactory receptors in the kidney are more than curiosities — they sense The trafficking failure itself may encode something about how tightly ORs are regulated in olfactory

on G protein hotspot mutations, why the canonical GαQ pathway fails in uveal melanoma, and how CXCR3 may protein family in medicine, but until recently their role in cancer was treated as marginal — a few curiosities believed in to a recognized driver class in oncology, and explains why chemokine receptors like CXCR3 may CXCR3 may be the hidden gatekeeper of immunotherapy response. no one believed in 10:52 The cancer genomics result that reframed GPCRs as drivers 16:45 Why CXCR3 may

That curiosity laid the foundation for a broader investigation into receptor activity-modifying proteins From Curiosity to Collaboration “We decided to evaluate the multiplexing methods... and found this Luminex From Many to One: De-Orphanization and Precision Focus “You can use this system to de-orphanize receptors In Ilana’s words, it’s a powerful way to “go from many back to one.”

Along the way, he reflects on key career moments, the role of mentorship, and how curiosity continues

That gap in care sparked a curiosity that became a career. struggling to grip mice in early animal studies to thesis delays during COVID-19, Serafini's journey is marked

how his experiences at the University of Chicago and the University of Michigan shaped his scientific curiosity

scaffolds like thiazolidines and xanthinediones, Ben is helping define how structurally different PAMs may “It doesn’t matter how many cool, fun tools you have. With clarity, curiosity, and a collaborative spirit, Ben reminds us that impactful science isn’t just

Maria Waldhoer at the Medical University of Graz, Austria, and received my Ph.D. in Molecular Medicine At the height of curiosity, a seemingly naïve idea at the dinner table led to a side project by which

– Overcoming introversion, the importance of talking to people, and how networking (or just genuine curiosity Whether in academia or industry, success comes from curiosity, persistence, and knowing your values.

Falling in Love with GPCRs GPCR pharmacology captured his scientific curiosity. His unwavering dedication through these cycles became an asset—many others shifted focus, leaving a smaller