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coupled receptors under diverse states Fan Liu , Han Zhou , Xiaonong Li , Liangliang Zhou , Chungong Yu

Schlander M, Hernandez-Villafuerte K, Cheng CY, Mestre-Ferrandiz J, Baumann M. Shen S, Zhao C, Wu C, Sun S, Li Z, Yan W, et al. J Phys Chem B. 2016;120(11):2878-85. 36.         J Biol Chem. 2018;293(19):7466-7473. 45.         Teng X, Chen S, Wang Q, Chen Z, Wang X, Huang N, et al.

This combined with the use of polarized light leads to a signal that can only be detected when the fluorescent When polarized light hits a free fluorescent ligand, its rotation speed is so fast that the emission On the other hand, when the polarized light hits the bound fluorescent ligand, the slower rotation speed Adapted from: Zhang Y, Tang H, Chen W, Zhang J. ACS Med Chem Lett. 2022 Jan 10;13(2):243-249. doi: 10.1021/acsmedchemlett.1c00598.

functional micro-domains” and the “helix movement model of receptor activation” were confirmed later when Recently, Tom’s lab discovered, along with Yu Chen and Ping Chi , that a mutant of CYSLTR2 is a driver

New cryo-EM structures from Chen et al. New cryo-EM structures from Chen et al.

of AGPCRs in the periphery ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih and disease Douglas Tilley ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih Hsiao Abstract Only available for AGPCR 24 Attendees Authors & Affiliations "Cheng-Chih Hsiao1,2, Hendrik Departments of Neurology and Immunology, Erasmus Medical Center, Rotterdam, The Netherlands" About Cheng-Chih Netherlands Institute for Neuroscience; 2022 - present: Researcher associate, Netherlands Brain Bank" Cheng-Chih