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dynamics ( e.g FLAsH biosensor [11]), cAMP production (e.g CAMYEL assay [12]) , and ERK activity (e.g YEN The ONE-GO biosensors, designed in a single vector, incorporate a G protein tagged with a YFP acceptor Zhou, Y., et al., Multiple GPCR Functional Assays Based on Resonance Energy Transfer Sensors.  Namkung, Y., et al., Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using

proteins (Gether 2000), with numerous intermediate sub-states in between (Vauquelin and Van Liefde 2005; Yao disruption of natural spatial and temporal signaling patterns regulated by physiological systems (Wold and Zhou intervention for metabolic diseases such as liver disease, obesity and diabetes (Secor et al. 2021; Wold and Zhou

October 2022 Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and Meanwhile, cGAS deletion upregulated profibrotic Yes-associated protein (YAP) signaling in endothelial , which was evidenced by the attenuation of organ fibrosis in mice specifically lacking endothelial YAP Pharmacological targeting of cGAS/STING-YAP signaling by both a small-molecule STING agonist, SR-717, Further, pharmacological targeting of cGAS/STING-YAP axis exhibits the potential to alleviate liver and

Abstract Coming Soon Authors and Affiliations Gross JD -1 (lead author, presenter) Kohlenbach LM -2 Zhou Y -1 Marugan JJ -3 Barak LS -1 (senior author) 1-Department of Cell Biology, Duke University Medical

Authors Buze Chen , Xiaoyuan Lu , Qingmei Zhou , Qing Chen , Siyan Zhu , Guilin Li , Hui Liu Source Contribute GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr.

Authors Juan Song , Miao Li , Cuicui Chen , Jian Zhou , Linlin Wang , Yu Yan , Jun She , Lin Tong , Yuanlin GPCR Create an account and get our contributors articles in your inbox Subscribe to the Dr.