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New scaffolds modulating the CBRs in both the orthosteric and allosteric sites have been developed, supported by resolved crystal structures of both CBRs.[4–8] A key challenge in CBR modulator development is separating can be appreciated when talking about SCRAs (Synthetic Cannabinoid Agonists), as one of the series developed Results 2.1  CELT-335 Binding at CB1 and CB2 Receptors The first step for the development of the assay Using these results as a starting point, the Tag-lite® binding assay was developed.

GPCR-focused programs, the ability to visualize receptor localization, internalization kinetics, and ligand For GPCR assay developers, HCS supports:  Quantitative visualization of receptor internalization and How Fluorescent Ligands Strengthen HCS Assays: The Case of CELT-331 Fluorescent ligands are now considered information that clarifies receptor behavior under different ligand conditions. technologies without needing internal imaging infrastructure or specialized assay development expertise

physiological processes, making them a key target in drug development.   This also improves detection of low affinity or slow binding ligands. In a recent study , we contributed to the development of a robust HTRF assay for the discovery of new A Robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery. By combining deep expertise in GPCR biology with advanced fluorescence chemistry, Celtarys custom-developed

Discover how Celtarys Research is transforming GPCR assay development with fluorescent ligands in this At Celtarys, the focus is on enabling fast, customizable development of fluorescent ligands and chemical development. Their approach is highly consultative—they don’t just sell ligands, they co-develop solutions. GPCR ecosystem , GPCR drug discovery , fluorescent ligands , GPCR scientist network , custom ligand development

🚀 Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research Get custom, fast, and functional ligands backed by real scientists solving real assay problems. 🧪 “We 🚀 Dr.GPCR x Celtarys are teaming up to revolutionize fluorescent ligand development for GPCR research Get custom, fast, and functional ligands backed by real scientists solving real assay problems. 🧪 “We

Got hooked on ligand design. Dr. Maria Majellaro didn’t plan to run a biotech company. Now she’s leading Celtarys, building custom fluorescent probes, and partnering with Dr. GPCR to support assay development worldwide. Now she’s leading Celtarys, building custom fluorescent probes, and partnering with Dr. GPCR to support assay development worldwide.